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Yunfei Wang
Researcher at Duke University
Publications - 15
Citations - 353
Yunfei Wang is an academic researcher from Duke University. The author has contributed to research in topics: Antibody & Neutralizing antibody. The author has an hindex of 4, co-authored 10 publications receiving 75 citations.
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Journal ArticleDOI
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Dapeng Li,Robert J. Edwards,Kartik Manne,David R. Martinez,Alexandra Schäfer,S. Munir Alam,Kevin Wiehe,Xiaozhi Lu,Robert Parks,Laura L. Sutherland,Thomas H. Oguin,Charlene McDanal,Lautaro G. Perez,Katayoun Mansouri,Sophie M. C. Gobeil,Katarzyna Janowska,Victoria Stalls,Megan Kopp,Fangping Cai,Esther J. Lee,Andrew Foulger,Giovanna Hernandez,Aja Sanzone,Kedamawit Tilahun,Chuancang Jiang,Longping V. Tse,Kevin W. Bock,Mahnaz Minai,Bianca M. Nagata,Kenneth D. Cronin,Victoria Gee-Lai,Margaret Deyton,Maggie Barr,Tarra Von Holle,Andrew N. Macintyre,Erica Stover,Jared Feldman,Blake M. Hauser,Timothy M. Caradonna,Trevor Scobey,Wes Rountree,Yunfei Wang,M. Anthony Moody,Derek W. Cain,C. Todd DeMarco,Thomas N. Denny,Christopher W. Woods,Elizabeth Petzold,Aaron G. Schmidt,Aaron G. Schmidt,I-Ting Teng,Tongqing Zhou,Peter D. Kwong,Peter D. Kwong,John R. Mascola,Barney S. Graham,Ian N. Moore,Robert A. Seder,Hanne Leth Andersen,Mark G. Lewis,David C. Montefiori,Gregory D. Sempowski,Ralph S. Baric,Priyamvada Acharya,Barton F. Haynes,Kevin O. Saunders +65 more
TL;DR: In this paper, SARS-CoV-2 neutralizing antibodies (NAbs) were isolated against the receptor-binding domain (RBD) or the N-terminal domain (NTD) of the SARS CoV2 spike.
Journal ArticleDOI
Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.
Kevin O. Saunders,Norbert Pardi,Robert Parks,Sampa Santra,Zekun Mu,Laura L. Sutherland,Richard M. Scearce,Maggie Barr,Amanda Eaton,Giovanna Hernandez,Derrick Goodman,Michael J. Hogan,István Tombácz,David N. Gordon,R. Wes Rountree,Yunfei Wang,Mark G. Lewis,Theodore C. Pierson,Chris Barbosa,Ying Tam,Xiaoying Shen,Guido Ferrari,Georgia D. Tomaras,David C. Montefiori,Drew Weissman,Barton F. Haynes +25 more
TL;DR: This paper showed that mRNA-LNP immunization compared to protein immunization elicits either the same or superior magnitude and breadth of HIV-1 Env-specific polyfunctional antibodies.
Journal ArticleDOI
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge
Barbara K. Felber,Zhongyan Lu,Xintao Hu,Antonio Valentin,Margherita Rosati,Christopher A.L. Remmel,Joshua A. Weiner,Margaret C. Carpenter,Katelyn Faircloth,Sherry Stanfield-Oakley,Wilton B. Williams,Xiaoying Shen,Georgia D. Tomaras,Celia C. LaBranche,David C. Montefiori,Hung V. Trinh,Hung V. Trinh,Mangala Rao,Munir Alam,Nathan Vandergrift,Kevin O. Saunders,Yunfei Wang,Wes Rountree,Jishnu Das,Galit Alter,Steven G. Reed,Pyone P. Aye,Faith Schiro,Bapi Pahar,Jason Dufour,Ronald S. Veazey,Preston A. Marx,David Venzon,George M. Shaw,Guido Ferrari,Margaret E. Ackerman,Barton F. Haynes,George N. Pavlakis +37 more
TL;DR: Interestingly, only macaques in the co-administration vaccine group are protected against SHIV CH505 acquisition after repeated low-dose intravaginal challenge and show 67% risk reduction per exposure.
Journal ArticleDOI
Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine
Dapeng Li,David R. Martinez,Alexandra Schäfer,Haiyan Chen,Maggie J. Barr,Laura L. Sutherland,Esther Lee,Robert Parks,Dieter Mielke,Whitney Edwards,Amanda Newman,Kevin W. Bock,Mahnaz Minai,Bianca M. Nagata,Matthew Gagne,Daniel C. Douek,C. Todd DeMarco,Thomas N. Denny,Thomas H. Oguin,Alecia R Brown,Wes Rountree,Yunfei Wang,Katayoun Mansouri,Robert Edwards,Guido Ferrari,Gregory D. Sempowski,Amanda Eaton,Juanjie Tang,Derek W. Cain,Sampa Santra,Norbert Pardi,Drew Weissman,Mark A. Tomai,Christopher Cox,Ian N. Moore,Hanne Andersen,Mark A. Lewis,Hana Golding,Robert A. Seder,Surender Khurana,Ralph S. Baric,David C. Montefiori,Kevin O. Saunders,Barton F. Haynes +43 more
TL;DR: In this paper , the authors reported a receptor-binding domain (RBD)-sortase A-conjugated ferritin nanoparticle (scNP) vaccine that induced neutralizing antibodies against SARS-CoV-2 and pre-emergent sarbecoviruses and protected non-human primates (NHPs).
Journal ArticleDOI
Neonatal rhesus macaques have distinct immune cell transcriptional profiles following HIV envelope immunization
Qifeng Han,Todd Bradley,Wilton B. Williams,Derek W. Cain,David C. Montefiori,Kevin O. Saunders,Robert Parks,Regina W. Edwards,Guido Ferrari,Olaf Mueller,Xiaoying Shen,Kevin Wiehe,Steven G. Reed,Christopher B. Fox,Wes Rountree,Nathan Vandergrift,Yunfei Wang,Laura L. Sutherland,Sampa Santra,M. Anthony Moody,Sallie R. Permar,Georgia D. Tomaras,Mark G. Lewis,Koen K. A. Van Rompay,Barton F. Haynes +24 more
TL;DR: For example, this paper showed that trimeric forms of HIV-1 Env immunogens elicit increased gp120-and gp41-specific antibodies more rapidly in neonatal macaques than adult macaques.