Zia Rehman

TL;DR: Functional and epigenomic data indicate that the risk variants near SOX17 alter gene regulation via an enhancer active in endothelial cells that determined Pulmonary arterial hypertension risk variants determined haplotype-specific enhancer activity, and CRISPR-mediated inhibition of the enhancer reduced SoX17 expression.

TL;DR: A unique case of Granulocytic Sarcoma in a male, who presented to us with a painless right breast mass without any prior history of Leukemia, is described.

TL;DR: In this paper , the authors provide an update on the proposed mechanisms underlying arrhythmogenesis in NAFLD and summarize the latest research findings in this field and recommend a comprehensive approach that includes treating the underlying liver condition and regular ECG monitoring to detect and address any potential cardiac complications.

TL;DR: Functional and epigenomic data indicate that the risk variants near SOX17 alter gene regulation via an enhancer active in endothelial cells that stratifies PAH patients for survival following diagnosis, with implications for future therapeutic trial design.

TL;DR: In this paper , an observational longitudinal study was conducted at the Department of Surgery, Aga Khan University & Hospital, Karachi between June 2022 to November 2022 to assess the rate and factors associated with non-adherence of Rivaroxaban in patients with deep venous thrombosis.