Zoe Gardener

TL;DR: In this paper, the authors analyzed plasma samples from 471 hospitalized patients recruited through the prospective multicenter ISARIC4C study and 39 outpatients with mild disease, enabling extensive characterization of responses across a full spectrum of COVID-19 severity.

TL;DR: Human infection challenge provides a unique opportunity to study the breadth of specificity and dynamics of RSV-specific T-cell responses in the target organ, allowing the precise investigation of Trm recognizing novel viral antigens over time.

TL;DR: In this paper, the authors evaluated the feasibility of using wrist-worn wearable biometric monitoring sensors to detect presymptomatic viral infection after exposure and predict infection severity in patients exposed to H1N1 influenza or human rhinovirus.

TL;DR: The booster vaccine exhibited an acceptable safety profile and was efficacious against moderate to severe–critical COVID-19, and the overall frequencies of solicited local and systemic adverse events were higher among vaccine recipients than placebo recipients after the primary and booster doses.

TL;DR: In this article, the authors argue that suboptimal vaccine immunogenicity and antigenic mismatch, compounded by poor uptake, means that influenza remains a major global disease, and that T cells recognizing peptides derived from conser...