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Institution

Delft University of Technology

EducationDelft, Zuid-Holland, Netherlands
About: Delft University of Technology is a education organization based out in Delft, Zuid-Holland, Netherlands. It is known for research contribution in the topics: Computer science & Catalysis. The organization has 37681 authors who have published 94404 publications receiving 2741710 citations. The organization is also known as: TU-Delft & Technische Hogeschool Delft.


Papers
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Journal ArticleDOI
TL;DR: A model predictive control approach to optimally coordinate variable speed limits for freeway traffic with the aim of suppressing shock waves is presented and a safety constraint that prevents drivers from encountering speed limit drops larger than, e.g., 10 km/h is included.
Abstract: When freeway traffic is dense, shock waves may appear. These shock waves result in longer travel times and in sudden large variations in the speeds of the vehicles, which could lead to unsafe situations. Dynamic speed limits can be used to eliminate or at least to reduce the effects of shock waves. However, coordination of the variable speed limits is necessary in order to prevent the occurrence of new shock waves and/or a negative impact on the traffic flows in other locations. In this paper, we present a model predictive control approach to optimally coordinate variable speed limits for freeway traffic with the aim of suppressing shock waves. First, we optimize continuous valued speed limits, such that the total travel time is minimal. Next, we include a safety constraint that prevents drivers from encountering speed limit drops larger than, e.g., 10 km/h. Furthermore, to get a better correspondence between the computed and applied control signals, we also consider discrete speed limits. We illustrate our approach with a benchmark problem.

357 citations

Journal ArticleDOI
TL;DR: This work benchmarked 22 classification methods that automatically assign cell identities including single-cell-specific and general-purpose classifiers and found that most classifiers perform well on a variety of datasets with decreased accuracy for complex datasets with overlapping classes or deep annotations.
Abstract: Single-cell transcriptomics is rapidly advancing our understanding of the cellular composition of complex tissues and organisms. A major limitation in most analysis pipelines is the reliance on manual annotations to determine cell identities, which are time-consuming and irreproducible. The exponential growth in the number of cells and samples has prompted the adaptation and development of supervised classification methods for automatic cell identification. Here, we benchmarked 22 classification methods that automatically assign cell identities including single-cell-specific and general-purpose classifiers. The performance of the methods is evaluated using 27 publicly available single-cell RNA sequencing datasets of different sizes, technologies, species, and levels of complexity. We use 2 experimental setups to evaluate the performance of each method for within dataset predictions (intra-dataset) and across datasets (inter-dataset) based on accuracy, percentage of unclassified cells, and computation time. We further evaluate the methods’ sensitivity to the input features, number of cells per population, and their performance across different annotation levels and datasets. We find that most classifiers perform well on a variety of datasets with decreased accuracy for complex datasets with overlapping classes or deep annotations. The general-purpose support vector machine classifier has overall the best performance across the different experiments. We present a comprehensive evaluation of automatic cell identification methods for single-cell RNA sequencing data. All the code used for the evaluation is available on GitHub ( https://github.com/tabdelaal/scRNAseq_Benchmark ). Additionally, we provide a Snakemake workflow to facilitate the benchmarking and to support the extension of new methods and new datasets.

357 citations

Journal ArticleDOI
TL;DR: A high-resolution imaging system based on the combination of ultrawideband transmission, multiple-input-multiple-output (MIMO) array, and synthetic aperture radar (SAR) is suggested and studied, showing a strong potential of the MIMO-SAR-based UWB system for security applications.
Abstract: A high-resolution imaging system based on the combination of ultrawideband (UWB) transmission, multiple-input-multiple-output (MIMO) array, and synthetic aperture radar (SAR) is suggested and studied. Starting from the resolution requirements, spatial sampling criteria for nonmonochromatic waves are investigated. Exploring the decisive influence of the system's fractional bandwidth (instead of previously claimed aperture sparsity) on the imaging capabilities of sparse aperture arrays, a MIMO linear array is designed based on the principle of effective aperture. For the antenna array, an optimized UWB antenna is designed allowing for distortionless impulse radiation with more than 150% fractional bandwidth. By combining the digital beamforming in the MIMO array with the SAR in the orthogonal direction, a high-resolution 3-D volumetric imaging system with a significantly reduced number of antenna elements is proposed. The proposed imaging system is experimentally verified against the conventional 2-D SAR under different conditions, including a typical concealed-weapon-detection scenario. The imaging results confirm the correctness of the proposed system design and show a strong potential of the MIMO-SAR-based UWB system for security applications.

357 citations

Journal ArticleDOI
TL;DR: The mixed culture process for PHA production does not require aseptic conditions and waste streams rather than pure substrates could be used as raw materials.

357 citations


Authors

Showing all 38152 results

NameH-indexPapersCitations
Albert Hofman2672530321405
Charles M. Lieber165521132811
Ad Bax13848697112
George C. Schatz137115594910
Georgios B. Giannakis137132173517
Jaap S. Sinninghe Damsté13472661947
Avelino Corma134104989095
Mark A. Ratner12796868132
Jing Kong12655372354
Robert J. Cava125104271819
Reza Malekzadeh118900139272
Jinde Cao117143057881
Mike S. M. Jetten11748852356
Liquan Chen11168944229
Oscar H. Franco11182266649
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023393
2022784
20215,396
20205,525
20195,230