Delft University of Technology

About: Delft University of Technology is a education organization based out in Delft, Zuid-Holland, Netherlands. It is known for research contribution in the topics: Computer science & Catalysis. The organization has 37681 authors who have published 94404 publications receiving 2741710 citations. The organization is also known as: TU-Delft & Technische Hogeschool Delft.

The emergence of peptides in the pharmaceutical business: From exploration to exploitation

Abstract: This minireview touches upon the challenges and opportunities peptides experience on the track to become an approved pharmaceutical. Peptide attributes originally considered troublesome with respect to drug development may now turn out to be more convenient rather than unfavourable. Besides characteristic high target affinity, biological peptides often exhibit higher than expected stability. Clearly natural selective pressure has optimised these biomolecules beyond what can be anticipated solely on the basis of their chemical nature. This concept is gradually finding its way into the pharma and biotech industry, as illustrated by a rise in medicinal peptide patent applications and developmental work.

A review of intensification of photocatalytic processes

Abstract: Photocatalysis is an attractive technology with potential applications in various disciplines, such as chemical synthesis, environmental technology and medicine, and receives an impressive amount of exposure in the open literature. However, industrial implementation remains limited due to scale up problems and the design of photoreactors. In this paper an overview is presented of recent advances in the design and application of novel reactors and devices. Two issues are essential: photon transfer limitations and mass transfer limitations (in the case of liquid phase reactions). In the field of mass transfer optimisation, spinning disc reactors, monolithic reactors and microreactors have been investigated for their use in photocatalysis. Significant advances are reported compared to conventional reactors. Studies focusing on performance improvement by optimising photon transfer, however, remain limited. While optical fibers and LEDs have been explored, major breakthroughs are still lacking. More focus on the introduction of a multitude of micro- or even nanoscale light emitting sources close to the catalyst particles is likely to be the way forward.