Federal University of Mato Grosso do Sul

About: Federal University of Mato Grosso do Sul is a education organization based out in Campo Grande, Brazil. It is known for research contribution in the topics: Population & Species richness. The organization has 6903 authors who have published 9030 publications receiving 78977 citations. The organization is also known as: UFMS & Federal University of Mato Grosso do Sul.

Alterações hematológicas em pacientes com dengue

Abstract: Dengue is a neglected disease with high morbidity and mortality among children and adults that occurs mainly in tropical and subtropical regions. The objective of this study was to evaluate hematological changes in patients with clinical manifestations of dengue. Medical records relating to 543 cases of dengue virus 3 that occurred during the 2007 epidemic in Campo Grande, Mato Grosso do Sul, were studied. Cases of classic dengue predominated (90.2%), with mild clinical manifestations lacking complications. The main hematological findings were leukopenia (68.3%), thrombocytopenia (66.5%), lymphocytopenia (67.2%) and atypical lymphocytes (67%). In dengue hemorrhagic fever, thrombocytopenia was more prolonged and the number of atypical lymphocytes was higher, while the other hematological abnormalities presented daily evolution similar to those in classic dengue. The hematological changes observed in dengue present according to the clinical course of the disease and its severity.

Saúde materno-infantil e nutrição de crianças Kaiowá e Guaraní, Área Indígena de Caarapó, Mato Grosso do Sul, Brasil

Abstract: The objective of this study was to evaluate the nutritional status of indigenous children and to determine the conditions of mother-child health. A cross-sectional study was performed with a sample of 137 children from 0 to 59 months of age from Kaiowa and Guarani indigenous communities, Caarapo Reserve, Mato Grosso do Sul, Brazil. Interviews were carried out using a questionnaire covering the conditions of mother-child health. Nutritional evaluation was performed using anthropometric measurements (weight and height). Results showed that 19.7% of mothers had not undergone prenatal examination and 53.3% had home births. Malnutrition in children was 18.2% and 34.1% for the weight/age and height/age indexes, respectively. The proportion of children with malnutrition, when separated by sex, age and education level of the mother, did not show a significant statistical difference for both indexes. This study documented a high occurrence of infant malnutrition and a worrisome mother-child health situation.

Mineralogia, química e estabilidade de agregados do tamanho de silte de solos da Região Sudeste do Brasil

Abstract: Com o objetivo de avaliar a relacao da composicao mineralogica e quimica do solo com a estabilidade de agregados do tamanho de silte, foram realizados estudos utilizando-se amostras de horizontes A e B de diversos solos da Regiao Sudeste do Brasil. Amostras de TFSA foram dispersas a 12.000 rpm por 20 minutos e a fracao silte foi separada por esgotamento da fracao argila, constituindo-se na fracao denominada pseudo-silte, a qual foi sonificada, separando-se a fracao argila desagregada (por sifonamento) da fracao silte propriamente dita. Estudos de correlacao mostraram que as composicoes mineralogica e quimica dos solos tem efeito marcante na dispersao de argila, com reflexos na fracao silte. Maiores teores de gibbsita refletem em maior estabilidade dos agregados do tamanho de silte ao passo que a caulinita proporciona efeito inverso. As formas de Al determinadas na fracao pseudo-silte estao associadas a maior dificuldade de dispersao da fracao argila dos solos.

rcellminer: exploring molecular profiles and drug response of the NCI-60 cell lines in R

Abstract: Purpose: The rcellminer R package provides a wide range of functionality to help R users access and explore molecular profiling and drug response data for the NCI-60. The package enables flexible programmatic access to CellMiner’s unparalleled breadth of NCI-60 data, including gene and protein expression, copy number, whole exome mutations, as well as activity data for ∼21K compounds, with information on their structure, mechanism of action and repeat screens. Functions are available to easily visualize compound structures, activity patterns and molecular feature profiles. Additionally, embedded R Shiny applications allow interactive data exploration. Availability and implementation: rcellminer is compatible with R 3.2 and above on Windows, Mac OS X and Linux. The package, documentation, tutorials and Shiny-based applications are available through Bioconductor (http://www.bioconductor.org/packages/rcellminer); ongoing updates will occur according to the Bioconductor release schedule with new CellMiner data. The package is free and open-source (LGPL 3). Contact: lunaa@cbio.mskcc.org or vinodh.rajapakse@nih.gov