Geelong Football Club

About: Geelong Football Club is a based out in . It is known for research contribution in the topics: Population & Wool. The organization has 1503 authors who have published 1826 publications receiving 34162 citations. The organization is also known as: Geelong Cats.

Intensive care implications of epidemic thunderstorm asthma

Abstract: OBJECTIVE: To investigate the environmental precipitants, treatment and outcome of critically ill patients affected by the largest and most lethal reported epidemic of thunderstorm asthma. DESIGN, SETTING AND PARTICIPANTS: Retrospective multicentre observational study. Meteorological, airborne particulate and pollen data, and a case series of 35 patients admitted to 15 intensive care units (ICUs) due to the thunderstorm asthma event of 21-22 November 2016, in Victoria, Australia, were analysed and compared with 1062 total ICU-admitted Australian patients with asthma in 2016. MAIN OUTCOME MEASURES: Characteristics and outcomes of total ICU versus patients with thunderstorm asthma, the association between airborne particulate counts and storm arrival, and ICU resource utilisation. RESULTS: All 35 patients had an asthma diagnosis; 13 (37%) had a cardiac or respiratory arrest, five (14%) died. Compared with total Australian ICU-admitted patients with asthma in 2016, patients with thunderstorm asthma had a higher mortality (15% v 1.3%, P < 0.001), were more likely to be male (63% v 34%, P < 0.001), to be mechanically ventilated, and had shorter ICU length of stay in survivors (median, 31.8 hours [interquartile range (IQR), 14.8-43.6 hours] v 40.7 hours [IQR, 22.3-75.1 hours]; P = 0.025). Patients with cardiac arrest were more likely to be born in Asian or subcontinental countries (5/10 [50%] v 4/25 [16%]; relative risk, 3.13; 95% CI, 1.05-9.31). A temporal link was demonstrated between airborne particulate counts and arrival of the storm. The event used 15% of the public ICU beds in the region. CONCLUSION: Arrival of a triggering storm is associated with an increase in respirable airborne particles. Affected critically ill patients are young, have a high mortality, a short duration of bronchospasm, and a prior diagnosis of asthma is common.

3—all-wool permanent-press fabrics part iii: stabilization of set with n,n'-dimethylolurea

Abstract: N,N'-Dimethylolurea (DMU) is effective in stabilizing set wool to machine-washing when the setting and DMU treatments are applied separately in that order. However, it cannot be applied to the wool at the same time as the setting agent because cross-links are introduced prematurely during the setting step. This stabilizes the partly rearranged molecular structure and tends to promote loss of set during machine-washing. Less reactive dimethylol compounds may be suitable for one-step application.

Adverse impact of chronic kidney disease on clinical outcomes following percutaneous coronary intervention.

Abstract: AIMS: We aimed to assess the impact of the severity of chronic kidney disease (CKD) with long-term clinical outcomes in patients undergoing percutaneous coronary intervention (PCI). METHODS: We analyzed data on consecutive patients undergoing PCI enrolled in the Victorian Cardiac Outcomes Registry (VCOR) from January 2014 to December 2018. Patients were stratified into tertiles of renal function; estimated glomerular filtration (eGFR) ≥60, 30-59 and < 30 ml/min/1.73 m2 (including dialysis). The primary outcome was long-term all-cause mortality obtained from linkage with the Australian National Death Index (NDI). The secondary endpoint was a composite of 30 day major adverse cardiac and cerebrovascular events. RESULTS: We identified a total of 51,480 patients (eGFR ≥60, n = 40,534; eGFR 30-59, n = 9,521; eGFR <30, n = 1,425). Compared with patients whose eGFR was ≥60, those with eGFR 30-59 and eGFR<30 were on average older (77 and 78 vs. 63 years) and had a greater burden of cardiovascular risk factors. Worsening CKD severity was independently associated with greater adjusted risk of long-term NDI mortality: eGFR<30 hazard ratio 4.21 (CI 3.7-4.8) and eGFR 30-59; 1.8 (CI 1.7-2.0), when compared to eGFR ≥60, all p < .001. CONCLUSION: In this large, multicentre PCI registry, severity of CKD was associated with increased risk of all-cause mortality underscoring the high-risk nature of this patient cohort.

Quality and safety in healthcare – a challenge accepted

Abstract: I sincerely appreciate the kind words and recognition contained in the two editorials of the June edition of Anaesthesia [1, 2]. I also understand the firm desire of the President and the President Elect to commit themselves and the Association of Anaesthetists of Great Britain and Ireland (AAGBI) to the support of whistleblowers in the specialty. However, I would like to add a note of caution to this fine rhetoric and perhaps emphasise the difficulty of converting that rhetoric into action [2]. These high office-bearers of the AAGBI should understand that the scandal in Bristol was not a secret affair within the medical profession, but a well-known disgrace within the specialties involved and the organisation within which it occurred. Although I have accepted the designation ‘whistleblower’ for my actions in Bristol, it is important that the AAGBI understands I had legitimately raised my concerns about the appalling standard of paediatric cardiac surgery at the Bristol Royal Infirmary within the hospital, the specialty, the profession and the Department of Health for at least six years before the media became involved [3]. Without involvement of the media, by 1995 a number of influential figures were aware of the excess mortality in Bristol, including local professors and heads of departments, the presidents/vice presidents/ past presidents of several professional organisations – including anaesthetic – and senior medical officers at the Department of Health. As a result of my attempts to raise awareness I became a pariah in my own hospital and department while more children died, until 170 were counted that might have survived had they undergone surgery elsewhere [4]. I obtained a position in Australia, setting up a new adult cardiac surgery unit, but was told by an antipodean surgical colleague attending a European Conference that I was ‘the most hated anaesthetist in Europe’. My contribution to medicine had been clinical governance but the profession had not wanted an anaesthetist to tell them it was needed [5]. Drs Harrop-Griffiths and Hartle must not expect the next part of the challenge to achieve quality and safety in the NHS to be any easier than it was for those who preceded them [1, 2]. I have not stopped aiming for the lofty goal to which they aspire, and I am happy to offer my advice if they should seek support in pursuing a goal that I believe is our ethical obligation [6–8].