Institution
Hiroshima University
Education•Hiroshima, Japan•
About: Hiroshima University is a education organization based out in Hiroshima, Japan. It is known for research contribution in the topics: Population & Cancer. The organization has 33602 authors who have published 69290 publications receiving 1495648 citations. The organization is also known as: Hiroshima Daigaku.
Topics: Population, Cancer, Gene, Catalysis, Transplantation
Papers published on a yearly basis
Papers
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TL;DR: Intraocular pressure (IOP), age, myopia, and history of hypertension differed between POAG patients and controls in univariate analyses, and together with IOP, age and age were significant risk factors for having POAG.
332 citations
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TL;DR: In this article, the relationship between nanometer- or atomistic-scale structures and the specific hydriding properties of the Mg-Ni binary system, such as(1) nanostructured (n)-Mg2Ni, (2) a mixture of n-Mg 2Ni and amorphous (a)-M 2Ni,(3) pure a-M gNi, and(4) n-mgNi2.
Abstract: One of the advantageous functional properties of Mg alloys (or compounds) is to exhibit the reversible hydriding reaction. In this paper, we present our systematic studies regarding the relationship between nanometer- or atomistic-scale structures and the specific hydriding properties of the Mg-Ni binary system, such as(1) nanostructured (n)-Mg2Ni, (2) a mixture of n-Mg2Ni and amorphous (a)-MgNi,(3) pure a-MgNi, and(4) n-MgNi2. Further studies on(5) an a-MgNi-based system for clarifying the effect of the short-range ordering on the structural and hydriding properties and(6) a MgNi2-based system for synthesizing the new Laves phase structure are also presented. The materials science of Mg-Ni-based new hydrides will provide indispensable knowledge for practically developing the Mg alloys as hydrogen-storage materials.
331 citations
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TL;DR: Dual therapy with daclatasvir and asunaprevir, without Peg‐IFN and RBV, can achieve high SVR rates in difficult‐to‐treat patients with HCV genotype 1b infection and previous null response to Peg‐ifN andRBV.
331 citations
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TL;DR: In this article, the MMG standard method is introduced, which is composed of four elements; maneuvering simulation model, procedure of the required captive model tests to capture the hydrodynamic force characteristics, analysis method for determining the hydrogravitational force coefficients for maneuvering simulations, and prediction method for the maneuvering motions of a ship in fullscale.
Abstract: A lot of simulation methods based on Maneuvering Modeling Group (MMG) model for ship maneuvering have been presented. Many simulation methods sometimes harm the adaptability of hydrodynamic force data for the maneuvering simulations since one method may be not applicable to other method in general. To avoid this, basic part of the method should be common. Under such a background, research committee on “standardization of mathematical model for ship maneuvering predictions” was organized by the Japan Society of Naval Architects and Ocean Engineers and proposed a prototype of maneuvering prediction method for ships, called “MMG standard method”. In this article, the MMG standard method is introduced. The MMG standard method is composed of 4 elements; maneuvering simulation model, procedure of the required captive model tests to capture the hydrodynamic force characteristics, analysis method for determining the hydrodynamic force coefficients for maneuvering simulations, and prediction method for maneuvering motions of a ship in fullscale. KVLCC2 tanker is selected as a sample ship and the captive mode test results are presented with a process of the data analysis. Using the hydrodynamic force coefficients presented, maneuvering simulations are carried out for KVLCC2 model and the fullscale ship for validation of the method. The present method can roughly capture the maneuvering motions and is useful for the maneuvering predictions in fullscale.
331 citations
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TL;DR: The authors reported the positional cloning of the Nijmegen breakage syndrome (NBS) gene, NBS1, from an 800-kb candidate region and detected the same 5-bp deletion in 13 individuals, and concluded that it is likely to be a founder mutation.
Abstract: Nijmegen breakage syndrome (NBS), also known as ataxia-telangiectasia (AT) variant, is an autosomal recessive disorder characterized by microcephaly, growth retardation, severe combined immunodeficiency and a high incidence of lymphoid cancers. Cells from NBS patients display chromosome instability, hypersensitivity to ionizing radiation and abnormal cell-cycle regulation after irradiation, all of which are characteristics shared with AT. Recently, the NBS locus was mapped at 8q21 by two independent approaches, complementation studies and linkage analysis. Here, we report the positional cloning of the NBS gene, NBS1, from an 800-kb candidate region. The gene comprises 50 kb and encodes a protein of 754 amino acids. The amino-terminal region of the protein shows weak homology to the yeast XRS2, MEK1, CDS1 and SPK1 proteins. The gene is expressed at high levels in the testes, suggesting that it might be involved in meiotic recombination. We detected the same 5-bp deletion in 13 individuals, and conclude that it is likely to be a founder mutation.
330 citations
Authors
Showing all 33744 results
Name | H-index | Papers | Citations |
---|---|---|---|
Tadamitsu Kishimoto | 181 | 1067 | 130860 |
Takashi Taniguchi | 152 | 2141 | 110658 |
Yasushi Fukazawa | 135 | 882 | 64424 |
Itsuo Nakano | 135 | 1539 | 97905 |
T. Ohsugi | 133 | 664 | 66010 |
Jerry W. Shay | 133 | 639 | 74774 |
Tsunefumi Mizuno | 130 | 478 | 60014 |
Tohru Takeshita | 128 | 1036 | 78625 |
Alex K.-Y. Jen | 128 | 921 | 61811 |
Andreas Kugel | 128 | 910 | 75529 |
Alain Benoit | 124 | 465 | 86284 |
Hiromitsu Takahashi | 124 | 499 | 55976 |
Yoshimi Takai | 122 | 680 | 61478 |
Toshio Hirano | 120 | 401 | 55721 |
Joakim Nystrand | 117 | 658 | 50146 |