Institution
Lankenau Medical Center
Healthcare•Philadelphia, Pennsylvania, United States•
About: Lankenau Medical Center is a healthcare organization based out in Philadelphia, Pennsylvania, United States. It is known for research contribution in the topics: Atrial fibrillation & Medicine. The organization has 436 authors who have published 414 publications receiving 7095 citations. The organization is also known as: Lankenau Hospital.
Topics: Atrial fibrillation, Medicine, Cancer, Warfarin, Stroke
Papers
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TL;DR: A 74-year-old male with past medical history of coronary artery disease, bioprosthetic aortic valve replacement and myeloproliferative disorder presented with fever and acute decompensated heart failure.
Abstract: A 74-year-old male with past medical history of coronary artery disease, bioprosthetic aortic valve replacement and myeloproliferative disorder presented with fever and acute decompensated heart failure. Blood cultures grew S taphylococcus aureus . Transespohageal echocardiogram (TEE) revealed large mobile …
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TL;DR: An overview of current research on cannabinoids and the ECS is created, the potential advantages and pitfalls of their use in GI diseases are detailed, and possible future developments in this field are explored.
Abstract: Cannabinoids have been known as the primary component of cannabis for decades, but the characterization of the endocannabinoid system (ECS) in the 1990s opened the doors for cannabis' use in modern medicine. The 2 main receptors of this system, cannabinoid receptors 1 and 2, are found on cells of various tissues, with significant expression in the gastrointestinal (GI) tract. The characterization of the ECS also heralded the understanding of endocannabinoids, naturally occurring compounds synthesized in the human body. Via secondary signaling pathways acting on vagal nerves, nociceptors, and immune cells, cannabinoids have been shown to have both palliative and detrimental effects on the pathophysiology of GI disorders. Although research on the effects of both endogenous and exogenous cannabinoids has been slow due to the complicated legal history of cannabis, discoveries of cannabinoids' treatment potential have been found in various fields of medicine, including the GI world. Medical cannabis has since been offered as a treatment for a myriad of conditions and malignancies, including cancer, human immunodeficiency virus/acquired immunodeficiency syndrome, multiple sclerosis, chronic pain, nausea, posttraumatic stress disorder, amyotrophic lateral sclerosis, cachexia, glaucoma, and epilepsy. This article hopes to create an overview of current research on cannabinoids and the ECS, detail the potential advantages and pitfalls of their use in GI diseases, and explore possible future developments in this field.
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TL;DR: This report is unique in demonstrating denosumab-induced hypocalcemia after bariatric surgery with normal vitamin D levels, suggesting a primary malabsorption of calcium.
Abstract: Hypocalcemia is a known risk following bariatric surgery and can contribute to the development of osteoporosis. Osteoporosis is commonly treated with denosumab, though denosumab can exacerbate underlying abnormalities in calcium homeostasis. We present the case of a 59-year-old female with severe hypocalcemia who had been treated with denosumab for osteoporosis three months before and had Billroth II gastric bypass surgery 15 years before, for bariatric purposes. Intravenous calcium supplementation was used to correct the initial electrolyte abnormality, and the patient was able to maintain appropriate calcium levels on high doses of oral calcium before discharge. Denosumab-induced hypocalcemia has been previously reported in patients with predisposing conditions including chronic kidney disease, primary sclerosing cholangitis, Crohn's disease, and a history of sleeve gastrectomy for marginal gastric ulcers. A few cases of hypocalcemia have been reported in patients with a history of bariatric surgery secondary to vitamin D deficiency, but this report is unique in demonstrating denosumab-induced hypocalcemia after bariatric surgery with normal vitamin D levels, suggesting a primary malabsorption of calcium. The risk of severe hypocalcemia should be considered before initiating denosumab to treat osteoporosis in patients with a history of bariatric surgery. If denosumab is initiated, serum calcium levels should be closely monitored, and patients should be educated about the importance of adherence to calcium supplementation.
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TL;DR: In this paper , the impact of the interlink between chronic inflammation, gram negative bacteria and comorbidities such as diabetes, and dyslipidemia on aortic valve calcification and/or stenosis was assessed.
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University of British Columbia1, University of Maryland, Baltimore2, Silver Spring Networks3, University of Texas Health Science Center at Houston4, University of Manitoba5, University of Chicago6, Stanford University7, Queen's University8, East Carolina University9, University of Western Ontario10, University of Texas Medical Branch11, Baystate Medical Center12, Vancouver Island Health Authority13, MedStar Union Memorial Hospital14, Université de Montréal15, Sunnybrook Health Sciences Centre16, Yale University17, Franciscan Health18, Cornell University19, Vanderbilt University Medical Center20, Brigham and Women's Hospital21, University of Calgary22, Beth Israel Deaconess Medical Center23, California State University, Long Beach24, University of California, Davis25, Georgia Regents University26, Dalhousie University27, University of Alberta28, Northwestern University29, University of Colorado Colorado Springs30, Washington University in St. Louis31, Toronto General Hospital32, University of Texas Southwestern Medical Center33, Montreal Heart Institute34, The Texas Heart Institute35, Baylor College of Medicine36, Houston Methodist Hospital37, University of Kentucky38, Brown University39, Mayo Clinic40, Lankenau Medical Center41, Michigan State University42, Johns Hopkins University School of Medicine43, University of Toronto44, Medical University of South Carolina45
TL;DR: In this article, the authors report cardiac surgeons' concerns, perceptions, and responses during the COVID-19 pandemic in North American cardiac surgery, concluding that surgeons were most concerned with exposing their family to the pandemic, running out of personal protective equipment (PPE), and hospital resources.
Abstract: Background The coronavirus disease 2019 (COVID-19) pandemic has had an unprecedented impact on health care and cardiac surgery. We report cardiac surgeons' concerns, perceptions, and responses during the COVID-19 pandemic. Methods A detailed survey was sent to recruit participating adult cardiac surgery centers in North America. Data regarding cardiac surgeons' perceptions and changes in practice were analyzed. Results Our study comprises 67 institutions with diverse geographic distribution across North America. Nurses were most likely to be redeployed (88%), followed by advanced care practitioners (69%), trainees (28%), and surgeons (25%). Examining surgeon concerns in regard to COVID-19, they were most worried with exposing their family to COVID-19 (81%), followed by contracting COVID-19 (68%), running out of personal protective equipment (PPE) (28%), and hospital resources (28%). In terms of PPE conservation strategies among users of N95 respirators, nearly half were recycling via decontamination with ultraviolet light (49%), followed by sterilization with heat (13%) and at home or with other modalities (13%). Reuse of N95 respirators for 1 day (22%), 1 week (21%) or 1 month (6%) was reported. There were differences in adoption of methods to conserve N95 respirators based on institutional pandemic phase and COVID-19 burden, with higher COVID-19 burden institutions more likely to resort to PPE conservation strategies. Conclusions The present study demonstrates the impact of COVID-19 on North American cardiac surgeons. Our study should stimulate further discussions to identify optimal solutions to improve workforce preparedness for subsequent surges, as well as facilitate the navigation of future healthcare crises.
1 citations
Authors
Showing all 440 results
Name | H-index | Papers | Citations |
---|---|---|---|
Abass Alavi | 113 | 1298 | 56672 |
Robert T. Sataloff | 51 | 680 | 10252 |
Flemming Forsberg | 49 | 333 | 9769 |
Michael D. Ezekowitz | 43 | 164 | 16799 |
Gan-Xin Yan | 42 | 105 | 10110 |
William A. Gray | 41 | 135 | 6830 |
Peter D. Le Roux | 36 | 81 | 4522 |
James M. Mullin | 35 | 98 | 4095 |
Georgia Panagopoulos | 32 | 102 | 3250 |
Karen Chiswell | 30 | 132 | 3477 |
Peter R. Kowey | 29 | 113 | 3083 |
Tracey L. Evans | 29 | 97 | 4465 |
Pietro Delise | 27 | 103 | 5080 |
Caleb B. Kallen | 24 | 44 | 3517 |
Louis E. Samuels | 23 | 95 | 2380 |