Showing papers by "Manchester Metropolitan University published in 2007"

Power, A Radical View

Abstract: Have leisure times? Read power a radical view writer by Why? A best seller publication in the world with fantastic value and also material is incorporated with interesting words. Where? Merely here, in this website you could check out online. Want download? Obviously readily available, download them likewise below. Offered data are as word, ppt, txt, kindle, pdf, rar, and zip. This is really going to save you time and your money in something should think about. If you're seeking then search around for online. Without a doubt there are several these available and a lot of them have the freedom. However no doubt you receive what you spend on. An alternate way to get ideas would be to check another power a radical view. Whatever our proffesion, power a radical view can be excellent resource for reading. Discover the existing data of word, txt, kindle, ppt, zip, pdf, and also rar in this site. You can completely review online or download this book by below. Now, never miss it. GO TO THE TECHNICAL WRITING FOR AN EXPANDED TYPE OF THIS POWER A RADICAL VIEW, ALONG WITH A CORRECTLY FORMATTED VERSION OF THE INSTANCE MANUAL PAGE ABOVE.

The adaptations to strength training : morphological and neurological contributions to increased strength.

Abstract: High-resistance strength training (HRST) is one of the most widely practiced forms of physical activity, which is used to enhance athletic performance, augment musculo-skeletal health and alter body aesthetics. Chronic exposure to this type of activity produces marked increases in muscular strength, which are attributed to a range of neurological and morphological adaptations. This review assesses the evidence for these adaptations, their interplay and contribution to enhanced strength and the methodologies employed. The primary morphological adaptations involve an increase in the cross-sectional area of the whole muscle and individual muscle fibres, which is due to an increase in myofibrillar size and number. Satellite cells are activated in the very early stages of training; their proliferation and later fusion with existing fibres appears to be intimately involved in the hypertrophy response. Other possible morphological adaptations include hyperplasia, changes in fibre type, muscle architecture, myofilament density and the structure of connective tissue and tendons. Indirect evidence for neurological adaptations, which encompasses learning and coordination, comes from the specificity of the training adaptation, transfer of unilateral training to the contralateral limb and imagined contractions. The apparent rise in whole-muscle specific tension has been primarily used as evidence for neurological adaptations; however, morphological factors (e.g. preferential hypertrophy of type 2 fibres, increased angle of fibre pennation, increase in radiological density) are also likely to contribute to this phenomenon. Changes in inter-muscular coordination appear critical. Adaptations in agonist muscle activation, as assessed by electromyography, tetanic stimulation and the twitch interpolation technique, suggest small, but significant increases. Enhanced firing frequency and spinal reflexes most likely explain this improvement, although there is contrary evidence suggesting no change in cortical or corticospinal excitability. The gains in strength with HRST are undoubtedly due to a wide combination of neurological and morphological factors. Whilst the neurological factors may make their greatest contribution during the early stages of a training programme, hypertrophic processes also commence at the onset of training.

From space to Earth: advances in human physiology from 20 years of bed rest studies (1986–2006)

Abstract: Bed rest studies of the past 20 years are reviewed. Head-down bed rest (HDBR) has proved its usefulness as a reliable simulation model for the most physiological effects of spaceflight. As well as continuing to search for better understanding of the physiological changes induced, these studies focused mostly on identifying effective countermeasures with encouraging but limited success. HDBR is characterised by immobilization, inactivity, confinement and elimination of Gz gravitational stimuli, such as posture change and direction, which affect body sensors and responses. These induce upward fluid shift, unloading the body’s upright weight, absence of work against gravity, reduced energy requirements and reduction in overall sensory stimulation. The upward fluid shift by acting on central volume receptors induces a 10–15% reduction in plasma volume which leads to a now well-documented set of cardiovascular changes including changes in cardiac performance and baroreflex sensitivity that are identical to those in space. Calcium excretion is increased from the beginning of bed rest leading to a sustained negative calcium balance. Calcium absorption is reduced. Body weight, muscle mass, muscle strength is reduced, as is the resistance of muscle to insulin. Bone density, stiffness of bones of the lower limbs and spinal cord and bone architecture are altered. Circadian rhythms may shift and are dampened. Ways to improve the process of evaluating countermeasures—exercise (aerobic, resistive, vibration), nutritional and pharmacological—are proposed. Artificial gravity requires systematic evaluation. This review points to clinical applications of BR research revealing the crucial role of gravity to health.

Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training

Abstract: The onset of whole muscle hypertrophy in response to overloading is poorly documented. The purpose of this study was to assess the early changes in muscle size and architecture during a 35-day high-intensity resistance training (RT) program. Seven young healthy volunteers performed bilateral leg extension three times per week on a gravity-independent flywheel ergometer. Cross-sectional area (CSA) in the central (C) and distal (D) regions of the quadriceps femoris (QF), muscle architecture, maximal voluntary contraction (MVC), and electromyographic (EMG) activity were measured before and after 10, 20, and 35 days of RT. By the end of the training period, MVC and EMG activity increased by 38.9 ± 5.7 and 34.8% ± 4.7%, respectively. Significant increase in QF CSA (3.5 and 5.2% in the C and D regions, respectively) was observed after 20 days of training, along with a 2.4 ± 0.7% increase in fascicle length from the 10th day of training. By the end of the 35-day training period, the total increase in QF CSA for regions C and D was 6.5 ± 1.1 and 7.4 ± 0.8%, respectively, and fascicle length and pennation angle increased by 9.9 ± 1.2 and 7.7 ± 1.3%, respectively. The results show for the first time that changes in muscle size are detectable after only 3 wk of RT and that remodeling of muscle architecture precedes gains in muscle CSA. Muscle hypertrophy seems to contribute to strength gains earlier than previously reported; flywheel training seems particularly effective for inducing these early structural adaptations.

Electrochromism and Electrochromic Devices

Abstract: Electrochromic materials, both organic and inorganic, have widespread applications in light-attenuation, displays and analysis. Written in an accessible manner, this book provides a comprehensive treatment of all types of electrochromic systems and their many applications. Coverage develops from electrochromic scope and history to new searching presentations of optical quantification and theoretical mechanistic models. Non-electrode electrochromism and photo-electrochromism are summarised, with updated comprehensive reviews of electrochromic oxides (tungsten-trioxide particularly), metal co-ordination complexes and metal-cyanometallates, viologens and other organics; and more recent exotics such as fullerenes, hydrides, and conjugated electroactive polymers are also covered. The book concludes by examining device construction and durability. With an extensive bibliography, recent advances in the field, modern applications and a step-by-step development from simple examples to sophisticated theories, this book is ideal for researchers in materials science, polymer science, electrical engineering, physics, chemistry, bioscience and (applied) optoelectronics.

Assessment as learning? How the use of explicit learning objectives, assessment criteria and feedback in post‐secondary education and training can come to dominate learning. 1

Abstract: The paper reports on the findings of a Learning and Skills Research Centre (LSRC) funded study investigating the impact of different modes and methods of assessment on achievement and progress in p...

Relationships between housing and healthy aging in very old age

Abstract: Purpose: The aim of this work is to examine the relationship between aspects of objective and perceived housing and aspects of healthy aging, defined as independence in daily activities and subjective wellbeing. Furthermore, this research examined the comparability of relationships between housing and healthy aging in the five European countries. Design and Methods: Data were drawn from the ENABLE-AGE Project, from home interviews with a sample of 1,918 very old people aged 75. to 89 years living alone in their own homes in Swedish, German, British, Hungarian and Latvian urban areas. Results: Participants living in better accessible homes, who perceive their home as meaningful and useful, and who think that external influences are not responsible for their housing situation are more independent in daily activities and have a better sense of well-being. Moreover, these results apply to all five national samples. Implications: The findings can widen the perspective when striving for barrier-free building standards, to encompass a holistic approach that takes both objective and perceived aspects of housing into account. Home modification and relocation should not be prescribed, but need to be negotiated with older adults to take into account their personal preferences.

The effect of cryotherapy on nerve conduction velocity, pain threshold and pain tolerance

Abstract: Objectives: To determine the impact of the application of cryotherapy on nerve conduction velocity (NCV), pain threshold (PTH) and pain tolerance (PTO). Design: A within-subject experimental design; treatment ankle (cryotherapy) and control ankle (no cryotherapy). Setting: Hospital-based physiotherapy laboratory. Participants: A convenience sample of adult male sports players (n = 23). Main outcome measures: NCV of the tibial nerve via electromyogram as well as PTH and PTO via pressure algometer. All outcome measures were assessed at two sites served by the tibial nerve: one receiving cryotherapy and one not receiving cryotherapy. Results: In the control ankle, NCV, PTH and PTO did not alter when reassessed. In the ankle receiving cryotherapy, NCV was significantly and progressively reduced as ankle skin temperature was reduced to 10°C by a cumulative total of 32.8% (p Conclusions: The data suggest that cryotherapy can increase PTH and PTO at the ankle and this was associated with a significant decrease in NCV. Reduced NCV at the ankle may be a mechanism by which cryotherapy achieves its clinical goals.

The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse.

Abstract: We hypothesized that rates of myofibrillar and patellar tendon collagen synthesis would fall over time during disuse, the changes being accompanied in muscle by decreases in focal adhesion kinase (FAK) phosphorylation and in gene expression for proteolytic enzymes. We studied nine men (22 +/- 4 years, BMI 24 +/- 3 kg m(-2) (means +/- s.d.) who underwent unilateral lower leg suspension for 23 days; five were studied between 0 and 10 days and four between 10 and 21 days. Muscle and tendon biopsies were taken in the postabsorptive state at days 0, 10 and 21 for measurement of protein synthesis, gene expression and protein phosphorylation. Muscle cross-sectional area decreased by 5.2% at 14 days and 10.0% (both P < 0.001), at 23 days, i.e. 0.5% day(-1), whereas tendon dimensions were constant. Rates of myofibrillar protein synthesis fell (P < 0.01) from 0.047% h(-1) at day 0 to 0.022% h(-1) at 10 days without further changes. Tendon collagen synthetic rates also fell (P < 0.01), from 0.052 to 0.023% h(-1) at 10 days and then to 0.010% h(-1) at 21 days. FAK phosphorylation decreased 30% (P < 0.01) at 10 days. No changes occurred in the amounts/phosphorylation of PKB-P70s6k-mTOR pathway components. Expression of mRNA for MuRF-1 increased approximately 3-fold at 10 days without changes in MAFbx or tripeptidyl peptidase II mRNA, but all decreased between 10 and 21 days. Thus, both myofibrillar and tendon protein synthetic rates show progressive decreases during 21 days of disuse; in muscle, this is accompanied by decreased phosphorylation of FAK, with no marked increases in genes for proteolytic enzymes.

Mundane mobilities, performances and spaces of tourism

Abstract: Tourism is commonly understood as an exception or special time, a period when the normal everyday constraints are suspended: tourists are temporarily immersed in spaces of difference, free from the bounds of home and work, and may transgress their ordinary ‘appropriate’ performances. This article questions the extent to which much mass tourism is ‘extraordinary’, suggesting instead that it is more typically associated with habitual routine, cultural conventions and normative performances which circumscribe what should be gazed upon and visited, and modes of touristic comportment and recording. These conventions are also managed by the directors of the tourist product and encouraged by the production of distinct, serial forms of tourist space in which cultural differences are tamed for easy consumption. The paper argues that such forms of performance and their staging are designed to maximize comfort, a touristic desire that should not necessarily be the focus of critical scorn. On the other hand, so manag...

A Critical Guide to Empirical Validation of Agent-Based Models in Economics: Methodologies, Procedures, and Open Problems

Abstract: This paper addresses the methodological problems of empirical validation in agent-based (AB) models in economics and how these are currently being tackled. We first identify a set of issues that are common to all modelers engaged in empirical validation. We then propose a novel taxonomy, which captures the relevant dimensions along which AB economics models differ. We argue that these dimensions affect the way in which empirical validation is carried out by AB modelers and we critically discuss the main alternative approaches to empirical validation being developed in AB economics. We conclude by focusing on a set of (as yet) unresolved issues for empirical validation that require future research.

Importance of the Home Environment for Healthy Aging: Conceptual and Methodological Background of the European ENABLE–AGE Project

Abstract: Currently in Europe as well as in the United States, an increasing proportion of very old people remain living in their homes despite declines in physical and mental health Together with the fact that the population of very old people is rapidly increasing (Mathers, Sadana, Salamon, Murray, Lopez, 2001; United Nations Development Programme, 2001), this poses new challenges to societal planning and housing development (Gitlin, 2003)

Cluster and Classification Techniques for the Biosciences

Abstract: Recent advances in experimental methods have resulted in the generation of enormous volumes of data across the life sciences. Hence clustering and classification techniques that were once predominantly the domain of ecologists are now being used more widely. This book provides an overview of these important data analysis methods, from long-established statistical methods to more recent machine learning techniques. It aims to provide a framework that will enable the reader to recognise the assumptions and constraints that are implicit in all such techniques. Important generic issues are discussed first and then the major families of algorithms are described. Throughout the focus is on explanation and understanding and readers are directed to other resources that provide additional mathematical rigour when it is required. Examples taken from across the whole of biology, including bioinformatics, are provided throughout the book to illustrate the key concepts and each technique’s potential.

A multicenter international study on the Spinal Cord Independence Measure, version III: Rasch psychometric validation.

Abstract: A multicenter international study on the Spinal Cord Independence Measure, version III: Rasch psychometric validation

Time course of muscular, neural and tendinous adaptations to 23 day unilateral lower-limb suspension in young men

Abstract: Muscles and tendons are highly adaptive to changes in chronic loading, though little is known about the adaptative time course. We tested the hypothesis that, in response to unilateral lower limb suspension (ULLS), the magnitude of tendon mechanical adaptations would match or exceed those of skeletal muscle. Seventeen men (1.79 +/- 0.05 m, 76.6 +/- 10.3 kg, 22.3 +/- 3.8 years) underwent ULLS for 23 days (n = 9) or acted as controls (n = 8). Knee extensor (KE) torque, voluntary activation (VA), cross-sectional area (CSA) (by magnetic resonance imaging), vastus lateralis fascicle length (L(f)) and pennation angle (), patellar tendon stiffness and Young's modulus (by ultrasonography) were measured before, during and at the end of ULLS. After 14 and 23 days (i) KE torque decreased by 14.8 +/- 5.5% (P < 0.001) and 21.0 +/- 7.1% (P < 0.001), respectively; (ii) VA did not change; (iii) KE CSA decreased by 5.2 +/- 0.7% (P < 0.001) and 10.0 +/- 2.0% (P < 0.001), respectively; L(f) decreased by 5.9% (n.s.) and 7.7% (P < 0.05), respectively, and by 3.2% (P < 0.05) and 7.6% (P < 0.01); (iv) tendon stiffness decreased by 9.8 +/- 8.2% (P < 0.05) and 29.3 +/- 11.5% (P < 0.005), respectively, and Young's modulus by 9.2 +/- 8.2% (P < 0.05) and 30.1 +/- 11.9% (P < 0.01), respectively, with no changes in the controls. Hence, ULLS induces rapid losses of KE muscle size, architecture and function, but not in neural drive. Significant deterioration in tendon mechanical properties also occurs within 2 weeks, exacerbating in the third week of ULLS. Rehabilitation to limit muscle and tendon deterioration should probably start within 2 weeks of unloading.

Holistic trajectories: a study of combined employment, housing and family careers by using multiple-sequence analysis

Abstract: Social science applications of sequence analysis have thus far involved the development of a typology on the basis of an analysis of one or two variables which have had a relatively low number of different states. There is a yet unexplored potential for sequence analysis to be applied to a greater number of variables and thereby a much larger state space. The development of a typology of employment experiences, for example, without reference to data on changes in housing, marital and family status is arguably inadequate. The paper demonstrates the use of sequence analysis in the examination of multivariable combinations of status as they change over time and shows that this method can provide insights that are difficult to achieve through other analytic methods. The data that are examined here provide support to intuitive understandings of clusters of common experiences which are both life course specific and related to socio-economic factors. Housing tenure is found to be of key importance in understanding the holistic trajectories that are examined. This suggests that life course trajectories are sharply differentiated by experience of social housing.

Estimating change in extreme European precipitation using a multimodel ensemble

Abstract: [1] Using the results from multimodel ensembles enables the assessment of model uncertainty in present and future estimates of extremes and the production of probabilities for regional or local-scale change. Six regional climate model (RCM) integrations from the PRUDENCE ensemble are used together with extreme value analysis to assess changes to precipitation extremes over Europe by 2070–2100 under the SRES A2 emissions scenario, investigating the contribution of the formulations of global (GCM) and regional climate models to scenario uncertainty. RCM ability to simulate precipitation extremes is evaluated for a UK case study. RCMs are shown to underestimate 1 day return values but reasonably simulate longer-duration (5 or 10 day) extremes. A multimodel approach by which probabilities can be produced for regional or local-scale change in extremes is then developed. A key result is that all RCMs project increases in the magnitude of short- and long-duration extreme precipitation for most of Europe. Individual model projections vary considerably but are independent of changes in mean precipitation. The magnitude of change is strongly influenced by the driving GCM but moderated by the RCM, which also influences spatial pattern. Therefore, when designing future ensemble experiments (1) the number of GCMs should at least equal the number of RCMs and (2) if spatial pattern is important then integrations from different RCMs should be incorporated. For impact studies, both the resolution and number of models in the ensemble will influence projections of change. The use of a multimodel approach therefore provides more robust estimates.

Factors contributing to muscle wasting and dysfunction in COPD patients

Abstract: Many patients with chronic obstructive pulmonary disease (COPD) suffer from exercise intolerance. In about 40% of the patients exercise capacity is limited by alterations in skeletal muscle rather than pulmonary problems. Indeed, COPD is often associated with muscle wasting and a slow-to-fast shift in fiber type composition resulting in weakness and an earlier onset of muscle fatigue, respectively. Clearly, limiting muscle wasting during COPD benefits the patient by improving the quality of life and also the chance of survival. To successfully combat muscle wasting and remodeling during COPD a clear understanding of the causes and mechanisms is needed. Disuse, hypoxemia, malnutrition, oxidative stress and systemic inflammation may all cause muscle atrophy. Particularly when systemic inflammation is elevated muscle wasting becomes a serious complication. The muscle wasting may at least partly be due to an increased activity of the ubiquitin proteasome pathway and apoptosis. However, it might well be that an impaired regenerative potential of the muscle rather than the increased protein degradation is the crucial factor in the loss of muscle mass during COPD with a high degree of systemic inflammation. Finally, we briefly discuss the various treatments and rehabilitation strategies available to control muscle wasting and fatigue in patients with COPD.

Potential pathogenic aspects of denture plaque

Abstract: Oral health status declines with age and as a result the need for removable prostheses increases. Oral health is a reflection of one's general health, affecting the ability of an individual to eat and speak, and contributes significantly to a sense of confidence and well-being. Currently, there are 15 million denture wearers in the UK, representing a significant consumer base and a special healthcare consideration. The microbiology of denture plaque has received little attention in comparison with dental plaque, yet it differs in location and composition. Denture plaque and poor denture hygiene is associated with stomatitis (Candida infection), may also serve as a reservoir of potentially infectious pathogens, and may contribute to oral malodour and to caries and periodontitis in people who have remaining natural teeth. Oral bacteria have been implicated in bacterial endocarditis, aspiration pneumonia, gastrointestinal infection and chronic obstructive pulmonary disease, among others, and dentures offer a reservoir for microorganisms associated with these infections. An effective oral hygiene regimen is important to control denture plaque biofilm and contributes to the control of associated oral and systemic diseases.

European food scares and their impact on EU food policy

Abstract: Purpose – This paper aims to chart the wide range of food scares reported throughout the EU over the period 1986‐2006 and explores their impact on EU policy.Design/methodology/approach – There is much extant research that solely investigates the occurrences of specific food scares, however; little emphasis is given to the responses of policy makers. This research aims to narrow this gap in the literature by reviewing the major food scares, which have occurred throughout the EU and the subsequent policy responses.Findings – A number of food scares have dominated media reports over the last two decades, but this study reveals the increasing emergence of rare serotypes of foodborne pathogens, as well as a rising trend of EU‐wide contaminant and animal disease‐related food scares. Simultaneously, there is evidence of evolution from a product‐focused food policy to a risk‐based policy, which has developed into a tentative EU consumer‐based food policy. Inevitably, in a market of 25 member‐states the concept of...

Predictors of drop-out from an outpatient cardiac rehabilitation programme

Abstract: Objective: To investigate the prevalence and predictors of early drop-out from a cardiac rehabilitation programme and also whether completers and drop-out patients differed in relation to their illness cognitions, gender and psychological distress and quality of lifeDesign: A six-week outpatient cardiac rehabilitation programmeSetting: A university teaching hospitalSubjects: One hundred and eighty-nine patients were recruited from a consecutive series of outpatient referrals prior to a six-week comprehensive cardiac rehabilitation programmeOutcome measures: The revised Illness Perception Questionnaire, Quality of Life after Myocardial Infarction Questionnaire and the Hospital Anxiety and Depression ScaleResults: One hundred and forty-seven cardiac patients completed the cardiac rehabilitation programme Forty-two (22%) patients dropped out in the first two weeks Factors predicting early drop-out were female gender, younger age, higher Hospital Anxiety Depression Scale score, lower illness perception

Towards Socially Just Pedagogies: Deleuzoguattarian Critical Disability Studies.

Abstract: Socially just pedagogies call for sensitivity to politics and culture. In this paper I will uncover some key challenges in relation to working pedagogically with disabled people through the exploration of a critical disability studies perspective. First, I will unpack some of the assumptions that underpin educational understandings of ‘disability’ and ‘impairment’, suggesting that we need to engage more willingly with politicized and socially constructed ideas in relation to these phenomena. Second, I will raise questions about the current aims of pedagogy in relation to the market and the autonomous learner. In light of the market—and the subject it produces—I will argue that ‘disability and ‘impairment’ demand critical researchers to think more creatively about setting the conditions for experimenting with socially just pedagogies. Third, with this experimentation in mind, I will draw upon the work of Gilles Deleuze and Felix Guattari to think of socially just pedagogies in terms of rhizomes (n – 1); pr...

Influence of muscle architecture on the torque and power-velocity characteristics of young and elderly men.

Abstract: This study investigated the contribution of muscle architecture to the differences in the torque-velocity and power-velocity relationships between older (OM n = 9, aged 69-82 years) and younger men (YM n = 15, aged 19-35 years). Plantarflexors' (PF) maximal isometric and concentric torques were recorded at 0.87, 1.75, 2.62, 3.49 and 4.36 rad s(-1). Physiological cross-sectional area (PCSA) was calculated as the ratio of muscle volume (determined by magnetic resonance imaging) to muscle fascicle length (Lf, measured by ultrasonography). GM PCSA and Lf of the OM were, respectively, 14.3% (P < 0.05) and 19.3% (P < 0.05) smaller than of the YM. In the OM, GM maximum isometric torque and maximum contraction velocity (Vmax), estimated from Hill's equation were, respectively, 48.5 and 38.2% lower (P < 0.001) than in the YM. At all contraction velocities, the OM produced less torque than the YM (46.3% of YM at 0.87 rad s(-1) to 14.7% at 4.36 rad s(-1), P < 0.001). Peak power (PP) of the OM was 80% lower than that of the YM and normalisation of PP to muscle volume only reduced this difference by 10%. Normalisation of torque to PCSA reduced, but did not eliminate, differences in torque between YM and OM (9.6%) and differences in torque/PCSA increased with contraction velocity (P < 0.05). After normalisation of velocity to Lf, the difference in Vmax between the OM and the YM was reduced to 15.9%. Thus, although muscle architecture contributes significantly to the differences in the torque- and power-velocity properties of OM and YM, other contractile factors, intrinsic to the muscle, seem to play a role. It is noteworthy that the deficit in PP between OM and YM is far greater than that of muscle torque, even after normalisation of PP to muscle volume. This finding likely plays an important role in the loss of mobility in old age.