Mepco Schlenk Engineering College

About: Mepco Schlenk Engineering College is a based out in . It is known for research contribution in the topics: Wavelet & Wavelet transform. The organization has 1307 authors who have published 1665 publications receiving 18690 citations.

Size-dependent antimycobacterial activity of titanium oxide nanoparticles against Mycobacterium tuberculosis

Abstract: Nanobiotechnology has offered new approaches for drug delivery and for the development of medicines against microbial infections including the deadly multidrug-resistant tuberculosis (MDR-TB). The present study deals with the antimycobacterial activity of titanium dioxide (TiO2) nanoparticles against Mycobacterium tuberculosis. Initially, TiO2 nanoparticles were synthesized from titanium(IV)oxysulfate (TiOSO4) solution using the sol–gel method. The shape and size of the TiO2 crystals were analyzed using TEM and SEM and were found to be spherical and 16 nm respectively, thereby indicating their morphology. Moreover, the XRD pattern confirms that the prepared TiO2 nanoparticles were anatase as well as being tetragonal and FTIR spectra show the stretching vibrations of Ti–O and Ti–O–Ti. Further, the TiO2 nanoparticles were shown to exhibit excellent size-dependent antimycobacterial activity against Mycobacterium tuberculosis, M. bovis and Mycobacterium sp. in a concentration dependent manner (10–100 μg mL−1). Confocal laser scanning microscopic analysis also confirmed that the TiO2 nanoparticles inhibit the biofilm formation of all three tested mycobacteria. The metabolic activity of mycobacteria was decreased up to 3–4 fold with an increase in the concentration of the TiO2 nanoparticles hence affecting the biofilm formation. Moreover, the TiO2 nanoparticles were less toxic (>25%) against normal lung bronchus cells at 100 μg mL−1 after 24 h treatment revealing that the nanoparticles are less toxic in nature. Taken together, these results showed that the TiO2 nanoparticles can be a potential biofilm agent against mycobacteria.

Green Synthesis of Nickel-Copper Mixed Ferrite Nanoparticles: Structural, Optical, Magnetic, Electrochemical and Antibacterial Studies

Abstract: The nickel–copper mixed ferrite nanoparticles [Cu1−xNixFe2O4 (x = 0, 0.5, 1)] NPs were prepared a by combustion method using Aloe barbadensis extract as a green reducing agent. The structural, functional, morphological, optical, magnetic, electrochemical properties of the sample were investigated using x-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, energy-dispersive x-ray spectroscopy, ultraviolet–visible (UV–Vis) spectrophotometry, photoluminescence, vibrating sample and cyclic voltammetry. The XRD patterns showed that all compositions with a cubic spinel structure and a crystallite size of 52 nm were reduced to 29 nm after nickel addition in copper ferrite and 35.85 nm for nickel ferrite. The UV–Vis absorption spectrum shows that the nickel-substituted copper ferrite band energy (Eg) increases as the crystallite size decreases. Measurements of magnetization obtained at room temperature revealed a soft ferromagnetic behaviour and saturation magnetization, coercivity value increased with the substitution of nickel. The maximum specific capacitance of 114 F g−1 was obtained at the scan rate of 5 mV s−1 for copper–nickel mixed ferrite NPs. A study of antibacterial activity against Escherichia coli, Klebsilla pneumonia, Staphylococcus aureus, and Bacillus subtilis using a well-diffusion method was performed. Nickel substitution on the copper spinel ferrite NPs revealed a major influence on structural, optical, magnetic, electrochemical and magnetic properties of the product obtained.

Stability and Performance Investigation of a Fuzzy-Controlled LCL Resonant Converter in an RTOS Environment

Abstract: The resonant converter (RC) is finding wide applications in many space and radar power supplies. Among various RCs LCL, LCC, and LCL-T topologies are broadly used. This manuscript presents a comparative evaluation of steady-state stability of LCL, LCC, and LCL-T resonant configurations. Careful analysis favors LCL RC among the aforementioned three configurations since the stability region is good for the LCL RC over the other configurations. Also, this paper presents a comparative evaluation of proportional integral (PI) controller and fuzzy logic controller for a modified LCL RC. The aforementioned controllers are simulated using MATLAB and their performance is analyzed. The outcome of the analysis shows the superiority of fuzzy control over the conventional PI control method. The LCL RC is proposed for applications in many space and radar power supplies. Design, simulation, and experimental results for a 133-W, 50-kHz LCL RC are presented in this manuscript which provide high efficiency (greater than 89%) even for 50% of load. Efficiencies greater than 80% are obtained at significantly reduced loads (11%). In this paper, the applicability of the Philips advanced RISC machine processor LPC 2148 is also investigated for implementing the controller for an RC.