Minia University

About: Minia University is a education organization based out in Minya, Egypt. It is known for research contribution in the topics: Population & Medicine. The organization has 4967 authors who have published 8986 publications receiving 108384 citations.

Clinical cosmeceutical repurposing of melatonin in androgenic alopecia using nanostructured lipid carriers prepared with antioxidant oils

Abstract: Background: The present work aims to formulate nanostructured lipid carriers (NLCs) exhibiting high skin deposition and high inherent antioxidant potential to repurpose the use of melatonin

Influence of thermal and compositional variations on conduction mechanisms and localized state density of amorphous Cd 50 S 50-x Se x thin films

Abstract: This work reports the study of dc-electrical conductivity of the amorphous chalcogenide Cd50S50−xSex (30 ≤ × ≤ 50 at.%) thin films and its dependent upon the temperature and composition. Thin films were prepared by the thermal evaporation process onto normal glass substrates in a vacuum about 8.2 × 10−4 Pa. The deposition rate and the film thickness were maintained constant at about 8 nm/s and 200 nm, respectively. X-ray diffraction was used to check the amorphous nature of thin-film samples. The resistance of the film samples has been measured in the temperature range 293 K to 473 K by using the two-point probe technique. DC-electrical conductivity was determined from the resistance measurements. The sheet resistance, the conduction mechanisms, activation energies, Mott parameters, barrier potential energy, trapping state energy and the density of localized states near the Fermi level, were investigated and studied. Obtained electrical data of the ternary Cd-S-Se thin films were investigated and studied in terms of Mott's variable range hopping model. All studied electrical parameters were found to be strongly dependent on the Se-content.

Use of HOMA-IR in hepatitis C.

Abstract: Summary. Chronic infection with hepatitis C virus (HCV) can induce insulin resistance (IR) in a genotype-dependent manner and contributes to steatosis, progression of fibrosis and resistance to interferon plus ribavirin therapy. Our understanding of HCV-induced IR has improved considerably over the years, but certain aspects concerning its evaluation still remain elusive to clinical researchers. One of the most important issues is elucidating the ideal method for assessment of IR in the setting of hepatitis C. The hyperinsulinaemic euglycaemic clamp is the gold standard method for determining insulin sensitivity, but is impractical as it is labour intensive and time-consuming. To date, all human studies except for four where IR was evaluated in the HCV setting, an estimation of IR has been used rather than direct measurements of insulin-mediated glucose uptake. The most commonly used estimation in the HCV population is the homeostasis model assessment of insulin resistance (HOMA-IR) which is calculated from a single measurement of fasting insulin and glucose. In this article, we review the use and reporting of HOMA in the literature and provide guidance on its appropriate as well as inappropriate use in the hepatitis setting.