Minia University

About: Minia University is a education organization based out in Minya, Egypt. It is known for research contribution in the topics: Population & Medicine. The organization has 4967 authors who have published 8986 publications receiving 108384 citations.

A Survey of Cyber-Physical Advances and Challenges of Wind Energy Conversion Systems: Prospects for Internet of Energy

Abstract: Wind energy has the biggest market share of renewable energy around the world. High growth and development rates of wind energy lead to a massive increase in complexity and scale of wind energy conversion systems (WECSs). Therefore, it is required to upgrade methods and strategies for design and implementation of WECS. Considering WECS as cyber-physical systems (CPSs) will enable wind energy for the Internet of Energy (IoE). IoE is a cloud network where power sources with embedded and distributed intelligence are interfaced to smart grid and mass of consumption devices like smart buildings, appliances, and electric vehicles. Research trends of CPS for energy applications are mainly focusing on smart grids and energy systems for demand-side management and smart buildings with less attention given to generation systems. This paper introduces potentials of cyber-physical (CP) integration of next-generation WECS. In addition, this paper surveys the advances and state-of-the-art technologies that enable WECS for IoE. Challenges and new requirements of future WECS as CPS like abstractions, networking, control, safety, security, sustainability, and social components are discussed.

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

Abstract: Chlorotoxin is a small 36 amino-acid peptide identified from the venom of the scorpion Leiurus quinquestriatus. Initially, chlorotoxin was used as a pharmacological tool to characterize chloride channels. While studying glioma-specific chloride currents, it was soon discovered that chlorotoxin possesses targeting properties towards cancer cells including glioma, melanoma, small cell lung carcinoma, neuroblastoma and medulloblastoma. The investigation of the mechanism of action of chlorotoxin has been challenging because its cell surface receptor target remains under questioning since two other receptors have been claimed besides chloride channels. Efforts on chlorotoxin-based applications focused on producing analogues helpful for glioma diagnosis, imaging and treatment. These efforts are welcome since gliomas are very aggressive brain cancers, close to impossible to cure with the current therapeutic arsenal. Among all the chlorotoxin-based strategies, the most promising one to enhance patient mean survival time appears to be the use of chlorotoxin as a targeting agent for the delivery of anti-tumor agents. Finally, the discovery of chlorotoxin has led to the screening of other scorpion venoms to identify chlorotoxin-like peptides. So far several new candidates have been identified. Only detailed research and clinical investigations will tell us if they share the same anti-tumor potential as chlorotoxin.