Minia University

About: Minia University is a education organization based out in Minya, Egypt. It is known for research contribution in the topics: Population & Medicine. The organization has 4967 authors who have published 8986 publications receiving 108384 citations.

Treatment of periungual vitiligo with erbium-YAG-laser plus 5-flurouracil: a left to right comparative study.

Abstract: Summary Despite the multiple treatment modalities available for vitiligo, none of them gives satisfactory results in the periungual type In this study we tried to explore and evaluate the effects of the combination treatment of erbium:YAG laser resurfacing and topical 5-flurouracil in periungual vitiligo Nine adult patients presenting with periungual vitiligo lesions were included in this prospective left–right comparative study The desirable inflammation was achieved after a mean of 47 days of 5-flurouracil application The mean re-epithelization time in the treatment sessions was 113 days The patients received a mean of 34 sessions in a mean duration of 76 months The mean overall response to therapy in the treated group was 478% while in the control group it was 11% (P < 00001) No side effects necessitated the stoppage of treatment This study points to the efficacy and safety of this combination in the treatment of periungual vitiligo

Dark and Photoelectric Investigation on Thin Films of β‐Cobalt Phthalocyanine Dispersed in Polymers

Abstract: Electrical and photoelectrical measurements are made on thin films of β-cobalt phthalocyanine particles in Schottky junction cells. The results of current density-voltage characteristics in dark at constant temperature are interpreted in terms of a space charge limited mechanism dominated by an exponential distribution of trapping levels. An analysis of the results enables the determination of the Fermi temperature of the trap distribution. The dependence of the photovoltaic parameters on pigment loading and polymer binder are investigated. Typical polymeric binders used throughout this study are polyvinylacetate (PVA) and polycarbonate (MK). The results show that the polymer has a strong effect on photocurrent generation efficiency in phthalocyanine composite type photovoltaic cell; polymers having a polar group seem desirable for improving the performance. An dunnen β-Kobalt-Phthalozyaninpartikelschichten in Schottky-ubergangszellen werden elektrische und photoelektrische Messungen durchgefuhrt. Die Ergebnisse der Stromdichte-Spannungscharakteristik im Dunkeln bei konstanter Temperatur werden mit einem Mechanismus der Raumladungsbegrenzung, der durch eine exponentielle Verteilung der Trapniveaus beherrscht wird, interpretiert. Eine Analyse der Ergebnisse ermoglicht, die Fermitemperatur der Trapverteilung zu bestimmen. Die Abhangigkeit der Photospannungsparameter von der Pigmentbeladung und dem Polymerbinder wird untersucht. Typische polymere Binder, die durchweg fur die Untersuchung benutzt werden, sind Polyvinylazetat (PVA) und Polykarbonat (MK). Die Ergebnisse zeigen, das das Polymer einen grosen Einflus auf den Photostromgenerationswirkungsgrad in Phthalozyanin-Photospannungszellen hat; Polymere mit einer polaren Gruppe scheinen fur eine Verbesserung der Leistungsparameter geeignet.

Screening and Molecular Docking of Novel Benzothiazole Derivatives as Potential Antimicrobial Agents.

Abstract: The burden of antibiotic resistance necessitates a continued search for new antimicrobials. We evaluated the antimicrobial activities of novel benzothiazoles synthesized by our group. Antibacterial activity was evaluated in vitro in Staphylococcus aureus, Bacillus subtilis, and Escherichia coli, while the antifungal activity was tested in Candida albicans and Aspergillus niger, and expressed as the minimum inhibitory concentration (MIC; µg/mL). MIC values of benzothiazole compounds ranged from 25 to 200 µg/mL. Compounds 3 and 4 gave high antibacterial and moderate antifungal activities, while 10 and 12 showed moderate activity against all tested organisms. In addition, some benzothiazole compounds significantly suppressed the activity of Escherichia coli dihydroorotase and inhibited the dimorphic transition of Candida albicans. Moreover, the active benzothiazole compounds induced DNA and protein leakage in Aspergillus niger spores. Molecular interactions of benzothiazole derivatives with dihydroorotase revealed the formation of hydrogen bonds with the active site residues LEU222 or ASN44. Strong hydrophobic interactions of the bulky thiazole and naphthalene rings at the entrance to the active site might interfere with the access of substrates to their binding sites, which results in dihydroorotase inhibition. Thus, inhibition of dihydroorotase might contribute to the observed antimicrobial actions of these compounds.

ZnO&Fe2O3-incoportaed TiO2 nanofibers as super effective photocatalyst for water splitting under visible light radiation

Abstract: The band gap energy, defects, recombination centers and photocorrosion resistance are the main features of the good photocatalyst to be exploited in the water splitting process under visible light radiation. Moreover, the nanomorphology has considerable impact. In this study, the band gap energy of titanium oxide nanofibers was modified by Fe 2 O 3 - and ZnO-incorporation to be used as effective photocatalysts in water splitting process under visible light radiation. The experimental results indicated that the band gap energy can be reduced to 1.89 eV when TiO 2 nanofibers are incorporated by 5 wt% ZnO and 5 wt% Fe 2 O 3 . However, the optimum performance in the water splitting process was observed with the nanofibers containing 5 wt% ZnO and 6 wt% Fe 2 O 3 (the corresponding band gap energy was 2.25 eV); the observed hydrogen production rate was 0.12 ml/min mg cat which is considered unprecedented value. The introduced super effective nanofibers were prepared using the electrospinning process. Typically, electrospun nanofibers composed of titanium(IV) isopropoxide, iron(II) acetate, polyvinylpyrrolidone and zinc acetate dihydrate were calcined in air at 700 °C. With respect to TiO 2 content, the composition of the electrospun solutions were adjusted to produce nanofibers containing ZnO and Fe 2 O 3 contents of 5, 10 and 15 wt%, and 3, 6 and 10 wt%, respectively. The produced nanofibers were characterized by SEM, FE-SEM, TEM, TEM-EDX, and XRD analyzing techniques. Due to the polycondesation characteristic of the utilized metallic precursors, the nanofibrous morphology was not affected by the calcination process.