Somatotropic Signaling: Trade-Offs Between Growth, Reproductive Development, and Longevity
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TLDR
Results obtained in GH-related mutant mice provide striking examples of mutations of a single gene delaying aging, reducing age-related disease, and extending lifespan in a mammal and providing novel experimental systems for the study of mechanisms of aging.Abstract:
Growth hormone (GH) is a key determinant of postnatal growth and plays an important role in the control of metabolism and body composition. Surprisingly, deficiency in GH signaling delays aging and...read more
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Protein and amino acid restriction, aging and disease: from yeast to humans
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References
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