Institution
State University of Campinas
Education•Campinas, Brazil•
About: State University of Campinas is a education organization based out in Campinas, Brazil. It is known for research contribution in the topics: Population & Context (language use). The organization has 49454 authors who have published 104606 publications receiving 1841004 citations. The organization is also known as: UNICAMP & State University of Campinas.
Topics: Population, Context (language use), Medicine, Adsorption, Insulin
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors evaluated the impact of a 2-dose COVID-19 vaccination campaign on reducing incidence, hospitalization, and deaths in the United States (US) by developing an agent-based model of SARS-CoV-2 transmission.
Abstract: Background Global vaccine development efforts have been accelerated in response to the devastating COVID-19 pandemic. We evaluated the impact of a 2-dose COVID-19 vaccination campaign on reducing incidence, hospitalizations, and deaths in the United States (US). Methods We developed an agent-based model of SARS-CoV-2 transmission and parameterized it with US demographics and age-specific COVID-19 outcomes. Healthcare workers and high-risk individuals were prioritized for vaccination, while children under 18 years of age were not vaccinated. We considered a vaccine efficacy of 95% against disease following 2 doses administered 21 days apart achieving 40% vaccine coverage of the overall population within 284 days. We varied vaccine efficacy against infection, and specified 10% pre-existing population immunity for the base-case scenario. The model was calibrated to an effective reproduction number of 1.2, accounting for current non-pharmaceutical interventions in the US. Results Vaccination reduced the overall attack rate to 4.6% (95% CrI: 4.3% - 5.0%) from 9.0% (95% CrI: 8.4% - 9.4%) without vaccination, over 300 days. The highest relative reduction (54-62%) was observed among individuals aged 65 and older. Vaccination markedly reduced adverse outcomes, with non-ICU hospitalizations, ICU hospitalizations, and deaths decreasing by 63.5% (95% CrI: 60.3% - 66.7%), 65.6% (95% CrI: 62.2% - 68.6%), and 69.3% (95% CrI: 65.5% - 73.1%), respectively, across the same period. Conclusions Our results indicate that vaccination can have a substantial impact on mitigating COVID-19 outbreaks, even with limited protection against infection. However, continued compliance with non-pharmaceutical interventions is essential to achieve this impact.
307 citations
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TL;DR: In this paper, a review of drying processes of fruits and vegetables in which vitamin C degradation was considered is presented, and the effect of other parameters related to the sample structure or to pretreatments on the final quality of the dried product is discussed.
Abstract: This article presents a review of drying processes of fruits and vegetables in which vitamin C degradation was considered. Vitamin C is an important and essential nutrient for humans and it can be taken as an index of nutrient quality of processes. Many researchers have reported the effect of different drying methods and the influence of drying conditions on the vitamin C content. In addition, the effect of other parameters related to the sample structure or to pretreatments on the final quality of the dried product is discussed. Vitamin C degradation mechanisms proposed in the literature, models applied to describe its kinetics, and recent advances in drying processes aiming high retention of this nutrient are also provided.
306 citations
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Baptist Health1, FIU Herbert Wertheim College of Medicine2, Johns Hopkins University3, Baptist Hospital of Miami4, Florida International University5, State University of Campinas6, University of Duisburg-Essen7, Brigham and Women's Hospital8, Wayne State University9, University of São Paulo10, Los Angeles Biomedical Research Institute11
TL;DR: There is evidence to support the association of NAFLD with subclinical atherosclerosis independent of traditional risk factors and metabolic syndrome, however, there is need for future longitudinal studies to review this association to ascertain causality and include other ethnic populations.
306 citations
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TL;DR: Different aspects of BNC production, including types of fermentation processes and culture media, are addressed, with the aim of demonstrating the importance of these parameters and improving B NC production and permitting application in the biotechnological, medical, pharmaceutical, and food industries.
Abstract: Production of bacterial nanocellulose (BNC) is becoming increasingly popular owing to its environmentally friendly properties. Based on this benefit of BNC production, researchers have also begun to examine the capacity for cellulose production through microbial hosts. Indeed, several research groups have developed processes for BNC production, and many studies have been published to date, with the goal of developing methods for large-scale production. During BNC bioproduction, the culture medium represents approximately 30 % of the total cost. Therefore, one important and challenging aspect of the fermentation process is identification of a new cost-effective culture medium that can facilitate the production of high yields within short periods of time, thereby improving BNC production and permitting application of BNC in the biotechnological, medical, pharmaceutical, and food industries. In this review, we addressed different aspects of BNC production, including types of fermentation processes and culture media, with the aim of demonstrating the importance of these parameters.
306 citations
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23 Aug 2020TL;DR: This work proposes PODNet, a model inspired by representation learning that fights catastrophic forgetting, even over very long runs of small incremental tasks --a setting so far unexplored by current works.
Abstract: Lifelong learning has attracted much attention, but existing works still struggle to fight catastrophic forgetting and accumulate knowledge over long stretches of incremental learning. In this work, we propose PODNet, a model inspired by representation learning. By carefully balancing the compromise between remembering the old classes and learning new ones, PODNet fights catastrophic forgetting, even over very long runs of small incremental tasks – a setting so far unexplored by current works. PODNet innovates on existing art with an efficient spatial-based distillation-loss applied throughout the model and a representation comprising multiple proxy vectors for each class. We validate those innovations thoroughly, comparing PODNet with three state-of-the-art models on three datasets: CIFAR100, ImageNet100, and ImageNet1000. Our results showcase a significant advantage of PODNet over existing art, with accuracy gains of 12.10, 6.51, and 2.85 percentage points, respectively.
306 citations
Authors
Showing all 49967 results
Name | H-index | Papers | Citations |
---|---|---|---|
David L. Kaplan | 177 | 1944 | 146082 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
Carlos Escobar | 148 | 1184 | 95346 |
Maria Elena Pol | 139 | 1414 | 99240 |
Scott D. Solomon | 137 | 1145 | 103041 |
David H. Pashley | 137 | 740 | 63657 |
Wagner Carvalho | 135 | 1395 | 94184 |
Helio Nogima | 132 | 1274 | 84368 |
Manfred Jeitler | 132 | 1278 | 89645 |
Catherine Newman-Holmes | 129 | 914 | 75447 |
Guy A. Rouleau | 129 | 884 | 65892 |
João Carvalho | 126 | 1278 | 77017 |
Jochen Schieck | 124 | 1285 | 77822 |
F. Stuart Chapin | 123 | 375 | 86236 |
Jose Chinellato | 123 | 1116 | 64267 |