Institution
Université Paris-Saclay
Education•Gif-sur-Yvette, France•
About: Université Paris-Saclay is a education organization based out in Gif-sur-Yvette, France. It is known for research contribution in the topics: Population & Context (language use). The organization has 29307 authors who have published 43183 publications receiving 867404 citations.
Topics: Population, Context (language use), Computer science, Medicine, Laser
Papers published on a yearly basis
Papers
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TL;DR: Kindler syndrome is a rare autosomal-recessive genodermatosis characterized by bullous poikiloderma with photosensitivity and the localization to chromosome 20p12.3 is reported by homozygosity mapping and the identification of a new gene, which is proposed to name kindlerin, which could be involved in cell adhesion processes via integrin signaling.
Abstract: Kindler syndrome is a rare autosomal-recessive genodermatosis characterized by bullous poikiloderma with photosensitivity. We report the localization to chromosome 20p12.3 by homozygosity mapping and the identification of a new gene, which we propose to name kindlerin. We found four different homozygous mutations in four consanguineous families from North Africa and Senegal; three are expected to lead to premature stop codons and truncated proteins and the fourth involves a splice site. We were unable to identify a mutation in kindlerin in a fifth consanguineous family from Algeria with a similar phenotype and in which the patient was homozygous for the markers in the 20p12.3 interval. The kindlerin protein contains several domains which are shared by a diverse group of peripheral membrane proteins that function as membrane-cytoskeleton linkers: two regions homologous to band 4.1 domain of which one includes a FERM domain with a NPKY sequence motif, and a third region with a PH or pleckstrin homology domain. Kindlerin might be involved in the bidirectional signaling between integrin molecules in the membrane and the cytoskeleton, and could be involved in cell adhesion processes via integrin signaling.
234 citations
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TL;DR: Two new complementary displacement production estimators and atomic mixing functions are proposed that extend the NRT-dpa by providing more physically realistic descriptions of primary defect creation in materials and may become additional standard measures for radiation damage quantification.
Abstract: Atomic collision processes are fundamental to numerous advanced materials technologies such as electron microscopy, semiconductor processing and nuclear power generation. Extensive experimental and computer simulation studies over the past several decades provide the physical basis for understanding the atomic-scale processes occurring during primary displacement events. The current international standard for quantifying this energetic particle damage, the Norgett−Robinson−Torrens displacements per atom (NRT-dpa) model, has nowadays several well-known limitations. In particular, the number of radiation defects produced in energetic cascades in metals is only ~1/3 the NRT-dpa prediction, while the number of atoms involved in atomic mixing is about a factor of 30 larger than the dpa value. Here we propose two new complementary displacement production estimators (athermal recombination corrected dpa, arc-dpa) and atomic mixing (replacements per atom, rpa) functions that extend the NRT-dpa by providing more physically realistic descriptions of primary defect creation in materials and may become additional standard measures for radiation damage quantification.
234 citations
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TL;DR: This work describes the first thermally activated delayed fluorescence material enabling circularly polarized light emission through chiral perturbation, which has been used as an emissive dopant in an organic light emitting diode exhibiting external quantum efficiency as high as 9.1%.
Abstract: This work describes the first thermally activated delayed fluorescence material enabling circularly polarized light emission through chiral perturbation. These new molecular architectures obtained through a scalable one-pot sequential synthetic procedure at room temperature (83% yield) display high quantum yield (up to 74%) and circularly polarized luminescence with an absolute luminescence dissymmetry factor, |glum|, of 1.3 × 10–3. These chiral molecules have been used as an emissive dopant in an organic light emitting diode exhibiting external quantum efficiency as high as 9.1%.
234 citations
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TL;DR: An exclusion limit on the H→invisible branching ratio of 0.26(0.17_{-0.05}^{+0.07}) at 95% confidence level is observed (expected) in combination with the results at sqrt[s]=7 and 8 TeV.
Abstract: Dark matter particles, if sufficiently light, may be produced in decays of the Higgs boson. This Letter presents a statistical combination of searches for H→invisible decays where H is produced according to the standard model via vector boson fusion, Z(ll)H, and W/Z(had)H, all performed with the ATLAS detector using 36.1 fb^{-1} of pp collisions at a center-of-mass energy of sqrt[s]=13 TeV at the LHC. In combination with the results at sqrt[s]=7 and 8 TeV, an exclusion limit on the H→invisible branching ratio of 0.26(0.17_{-0.05}^{+0.07}) at 95% confidence level is observed (expected).
234 citations
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TL;DR: Polyploidy results in immediate genetic redundancy and represents, with the emergence of new gene functions, an important source of novelty in plant evolution, and is illustrated by the huge angiosperm diversity that is assumed to originate from recurrent polyploidization events.
234 citations
Authors
Showing all 29679 results
Name | H-index | Papers | Citations |
---|---|---|---|
Guido Kroemer | 236 | 1404 | 246571 |
Patrick O. Brown | 183 | 755 | 200985 |
Didier Raoult | 173 | 3267 | 153016 |
Sophie Henrot-Versille | 171 | 957 | 157040 |
Philippe Ciais | 149 | 965 | 114503 |
Stanislas Dehaene | 149 | 456 | 86539 |
Marc Humbert | 149 | 1184 | 100577 |
Jean Bousquet | 145 | 1288 | 96769 |
Jean-François Cardoso | 145 | 373 | 115144 |
Marc Besancon | 143 | 1799 | 106869 |
Maksym Titov | 139 | 1573 | 128335 |
W. Kozanecki | 138 | 1498 | 99758 |
Nabila Aghanim | 137 | 416 | 100914 |
Yves Sirois | 137 | 1334 | 95714 |
Patrick Janot | 136 | 1485 | 93626 |