Institution
Université Paris-Saclay
Education•Gif-sur-Yvette, France•
About: Université Paris-Saclay is a education organization based out in Gif-sur-Yvette, France. It is known for research contribution in the topics: Population & Context (language use). The organization has 29307 authors who have published 43183 publications receiving 867404 citations.
Topics: Population, Context (language use), Computer science, Medicine, Laser
Papers published on a yearly basis
Papers
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TL;DR: This paper presents an extensive overview of VANET security characteristics and challenges as well as requirements, and gives the details of the recent security architectures and the well-known security standards protocols.
471 citations
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Nasim Mavaddat1, Paul D.P. Pharoah1, Kyriaki Michailidou1, Jonathan Tyrer1 +239 more•Institutions (68)
TL;DR: The PRS stratifies breast cancer risk in women both with and without a family history of breast cancer, and the observed level of risk discrimination could inform targeted screening and prevention strategies.
Abstract: Background: Data for multiple common susceptibility alleles for breast cancer may be combined to identify women at different levels of breast cancer risk. Such stratification could guide preventive and screening strategies. However, empirical evidence for genetic risk stratification is lacking. Methods: We investigated the value of using 77 breast cancer-associated single nucleotide polymorphisms (SNPs) for risk stratification, in a study of 33 673 breast cancer cases and 33 381 control women of European origin. We tested all possible pair-wise multiplicative interactions and constructed a 77-SNP polygenic risk score (PRS) for breast cancer overall and by estrogen receptor (ER) status. Absolute risks of breast cancer by PRS were derived from relative risk estimates and UK incidence and mortality rates. Results: There was no strong evidence for departure from a multiplicative model for any SNP pair. Women in the highest 1% of the PRS had a three-fold increased risk of developing breast cancer compared with women in the middle quintile (odds ratio [OR] = 3.36, 95% confidence interval [CI] = 2.95 to 3.83). The ORs for ER-positive and ER-negative disease were 3.73 (95% CI = 3.24 to 4.30) and 2.80 (95% CI = 2.26 to 3.46), respectively. Lifetime risk of breast cancer for women in the lowest and highest quintiles of the PRS were 5.2% and 16.6% for a woman without family history, and 8.6% and 24.4% for a woman with a first-degree family history of breast cancer. Conclusions: The PRS stratifies breast cancer risk in women both with and without a family history of breast cancer. The observed level of risk discrimination could inform targeted screening and prevention strategies. Further discrimination may be achievable through combining the PRS with lifestyle/environmental factors, although these were not considered in this report.
471 citations
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TL;DR: In this paper, the authors review the techniques necessary for the manipulation of neutral atoms for the purpose of quantum simulation and explain how the different types of interactions between Rydberg atoms allow a natural mapping onto various quantum spin models.
Abstract: Recent decades have witnessed great developments in the field of quantum simulation—where synthetic systems are built and studied to gain insight into complicated, many-body real-world problems. Systems of individually controlled neutral atoms, interacting with each other when excited to Rydberg states, have emerged as a promising platform for this task, particularly for the simulation of spin systems. Here, we review the techniques necessary for the manipulation of neutral atoms for the purpose of quantum simulation—such as quantum gas microscopes and arrays of optical tweezers—and explain how the different types of interactions between Rydberg atoms allow a natural mapping onto various quantum spin models. We discuss recent achievements in the study of quantum many-body physics in this platform, and some current research directions beyond that. This Review Article outlines the techniques necessary for the manipulation of neutral atoms and making use of their interactions, when excited to Rydberg states, to achieve the goal of quantum simulation of many-body physics.
471 citations
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TL;DR: In this article, the population of 47 compact binary mergers detected with a false-alarm rate of 0.614 were dynamically assembled, and the authors found that the BBH rate likely increases with redshift, but not faster than the star formation rate.
Abstract: We report on the population of 47 compact binary mergers detected with a false-alarm rate of 0.01 are dynamically assembled. Third, we estimate merger rates, finding RBBH = 23.9-+8.614.3 Gpc-3 yr-1 for BBHs and RBNS = 320-+240490 Gpc-3 yr-1 for binary neutron stars. We find that the BBH rate likely increases with redshift (85% credibility) but not faster than the star formation rate (86% credibility). Additionally, we examine recent exceptional events in the context of our population models, finding that the asymmetric masses of GW190412 and the high component masses of GW190521 are consistent with our models, but the low secondary mass of GW190814 makes it an outlier.
468 citations
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Swiss Federal Institute for Forest, Snow and Landscape Research1, University of Marburg2, Spanish National Research Council3, Institut national de la recherche agronomique4, Center for International Forestry Research5, Aristotle University of Thessaloniki6, National Research Council7, Vytautas Magnus University8, University of Oulu9, Uppsala University10, King Juan Carlos University11, Université Paris-Saclay12, Science for Life Laboratory13
TL;DR: This dataset of individual tree-core characteristics including ring-width series and whole-core wood density was collected for seven ecologically and economically important European tree species, covering most of the geographical and climatic range occupied by the selected species.
Abstract: The dataset presented here was collected by the GenTree project (EU-Horizon 2020), which aims to improve the use of forest genetic resources across Europe by better understanding how trees adapt to their local environment. This dataset of individual tree-core characteristics including ring-width series and whole-core wood density was collected for seven ecologically and economically important European tree species: silver birch (Betula pendula), European beech (Fagus sylvatica), Norway spruce (Picea abies), European black poplar (Populus nigra), maritime pine (Pinus pinaster), Scots pine (Pinus sylvestris), and sessile oak (Quercus petraea). Tree-ring width measurements were obtained from 3600 trees in 142 populations and whole-core wood density was measured for 3098 trees in 125 populations. This dataset covers most of the geographical and climatic range occupied by the selected species. The potential use of it will be highly valuable for assessing ecological and evolutionary responses to environmental conditions as well as for model development and parameterization, to predict adaptability under climate change scenarios.
467 citations
Authors
Showing all 29679 results
Name | H-index | Papers | Citations |
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Guido Kroemer | 236 | 1404 | 246571 |
Patrick O. Brown | 183 | 755 | 200985 |
Didier Raoult | 173 | 3267 | 153016 |
Sophie Henrot-Versille | 171 | 957 | 157040 |
Philippe Ciais | 149 | 965 | 114503 |
Stanislas Dehaene | 149 | 456 | 86539 |
Marc Humbert | 149 | 1184 | 100577 |
Jean Bousquet | 145 | 1288 | 96769 |
Jean-François Cardoso | 145 | 373 | 115144 |
Marc Besancon | 143 | 1799 | 106869 |
Maksym Titov | 139 | 1573 | 128335 |
W. Kozanecki | 138 | 1498 | 99758 |
Nabila Aghanim | 137 | 416 | 100914 |
Yves Sirois | 137 | 1334 | 95714 |
Patrick Janot | 136 | 1485 | 93626 |