University of Antananarivo

About: University of Antananarivo is a education organization based out in Antananarivo, Madagascar. It is known for research contribution in the topics: Population & Lemur. The organization has 1561 authors who have published 1703 publications receiving 30922 citations. The organization is also known as: Tananarive University & Antananarivo University.

Effects of mefloquine use on Plasmodium vivax multidrug resistance.

Abstract: Numerous studies have indicated a strong association between amplification of the multidrug resistance-1 gene and in vivo and in vitro mefloquine resistance of Plasmodium falciparum. Although falciparum infection usually is not treated with mefloquine, incorrect diagnosis, high frequency of undetected mixed infections, or relapses of P. vivax infection triggered by P. falciparum infections expose non-P. falciparum parasites to mefloquine. To assess the consequences of such unintentional treatments on P. vivax, we studied variations in number of Pvmdr-1 (PlasmoDB accession no. PVX_080100, NCBI reference sequence NC_009915.1) copies worldwide in 607 samples collected in areas with different histories of mefloquine use from residents and from travelers returning to France. Number of Pvmdr-1 copies correlated with drug use history. Treatment against P. falciparum exerts substantial collateral pressure against sympatric P. vivax, jeopardizing future use of mefloquine against P. vivax. A drug policy is needed that takes into consideration all co-endemic species of malaria parasites.

Traditional and Unconventional Dried Fruit Snacks as a Source of Health-Promoting Compounds

Abstract: Dried fruits are important, healthy and popular snacks, despite the limited information on their nutritional profiles and phytochemical composition. The present work was aimed to study the chemical composition of freeze-dried fruits from four fruit species: two common commercial snacks (apple and goji) and two innovative products (kaki and kiwi). Sugar and organic acid levels, total phenolics (TPC), and main health-promoting phytochemicals were studied by HPLC fingerprinting analysis. Furthermore, in vitro antioxidant capacity (AOC) was preliminarily observed in these products. A Principal Component Analysis (PCA) was carried out as a multivariate approach as well. The TPC ranged from 210.9 mg GAE/100g DW (kiwi) to 872.6 mg GAE/100g DW (kaki), while dried fruit antioxidant capacity ranged from 23.09 mmol Fe2+/kg DW (goji) to 137.5 mmol Fe2+/kg DW (kaki). The most important phytochemical class in apple (two cultivars), kiwi, and kaki dried fruits was phenolics (from 74.6% to 93.3%), while monoterpenes were the first class in goji (67.5%). No anthocyanins have been identified in dried fruits because these compounds are most likely converted to phenolic acids during the drying process. This research intended to stimulate large-scale exploitation of commercial dried fruits as functional foods as well.

Un autre q-analogue des nombres d’Euler

Abstract: The ordinary generating functions of the secant and tangent numbers have very simple continued fraction expansions. However, the classical q-secant and q-tangent numbers do not give a natural q-analogue of these continued fractions. In this paper, we introduce a different q-analogue of Euler numbers using q-difference operator and show that their generating functions have simple continued fraction expansions. Furthermore, by establishing an explicit bijection between some Motzkin paths and (k,r)-multipermutations we derive combinatorial interpretations for these q-numbers. Finally the allied q-Euler median numbers are also studied.