University of Modena and Reggio Emilia

About: University of Modena and Reggio Emilia is a education organization based out in Modena, Italy. It is known for research contribution in the topics: Population & Medicine. The organization has 8179 authors who have published 22418 publications receiving 671337 citations. The organization is also known as: Università degli Studi di Modena e Reggio Emilia & Universita degli Studi di Modena e Reggio Emilia.

Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats.

Abstract: mias and lethality, reduced the increase in free radical blood levels and left-ventricle histologic alterations, and augmented the extracellular signal–regulated kinase activation. Treatment with the melanocortin peptides adrenocorticotropin and 2-melanocyte-stimulating hormone (162 nmol/kg intravenously or 16.2 nmol/kg intracerebroventricularly, during coronary occlusion) produced the same protective effects of electrical stimulation and with the same muscarinic acetylcholine receptor– dependent mechanism, seemingly through brain activation (mediated by melanocortin MC3 receptors, as previously described) of such efferent vagal pathway. Conclusions: The present results give evidence for the identification of a protective, melanocortin-activated, efferent vagal cholinergic pathway, operative in conditions of myocardial ischemia/reperfusion. These data suggest that melanocortins and pertinent compounds able to activate such a pathway could provide the potential for development of a new class of drugs for a novel approach to management of ischemic heart disease. (Crit Care Med 2005; 33:2621–2628)

A prospective study of dietary selenium intake and risk of type 2 diabetes

Abstract: Background Growing evidence raises concern about possible associations of high selenium exposure with diabetes in selenium-replete populations such as the US. In countries with lower selenium status, such as Italy, there is little epidemiological evidence on the association between selenium and diabetes. This study examined the prospective association between dietary selenium intake and risk of type 2 diabetes.

Detection of Honey Adulteration by Sugar Syrups Using One-Dimensional and Two-Dimensional High-Resolution Nuclear Magnetic Resonance

Abstract: The importance of honey adulteration detection has recently increased owing to the limited production levels in recent years and the relative high price of honey; therefore, this illegal practice has become more and more attractive to producers. Hence, the need has arisen for more effective analytical methods aiming at detecting honey adulteration. The present research presents an effective method to detect adulteration in honey falsified by intentional addition of different concentrations of commercial sugar syrups, using one-dimensional (1D) and two-dimensional (2D) nuclear magnetic resonance (NMR) coupled with multivariate statistical analysis. Sixty-three authentic and 63 adulterated honey samples were analyzed. To prepare adulterated honeys, seven different sugar syrups normally used for nutrition of bees were used. The best discriminant model was obtained by 1D spectra, and leave-one-out cross-validation showed a predictive capacity of 95.2%. 2D NMR also furnished acceptable results (cross-validatio...