Institution
University of Siena
Education•Siena, Italy•
About: University of Siena is a education organization based out in Siena, Italy. It is known for research contribution in the topics: Population & Cancer. The organization has 12179 authors who have published 33334 publications receiving 1008287 citations. The organization is also known as: Università degli studi di Siena & Universita degli studi di Siena.
Papers published on a yearly basis
Papers
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01 Dec 2011TL;DR: A distributed suboptimal joint mode selection and resource allocation scheme is proposed that performs close to the optimal scheme both in terms of resource efficiency and user fairness and is benchmarked with respect to the centralized optimal solution.
Abstract: Device-to-device (D2D) communications underlaying a cellular infrastructure has recently been proposed as a means of increasing the cellular capacity, improving the user throughput and extending the battery lifetime of user equipments by facilitating the reuse of spectrum resources between D2D and cellular links. In network assisted D2D communications, when two devices are in the proximity of each other, the network can not only help the devices to set the appropriate transmit power and schedule time and frequency resources but also to determine whether communication should take place via the direct D2D link (D2D mode) or via the cellular base station (cellular mode). In this paper we formulate the joint mode selection, scheduling and power control task as an optimization problem that we first solve assuming the availability of a central entity. We also propose a distributed suboptimal joint mode selection and resource allocation scheme that we benchmark with respect to the centralized optimal solution. We find that the distributed scheme performs close to the optimal scheme both in terms of resource efficiency and user fairness.
241 citations
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TL;DR: Current knowledge on the impact of marine litter on Mediterranean biodiversity is reviewed, selection criteria for choosing marine organisms suitable for use as bioindicator species are defined, and a methodological approach to assessing the harm related to marine litter ingestion in several Mediterranean habitats and sub-regions is proposed.
241 citations
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TL;DR: Data provide supportive evidence that a meaningful number of RIS subjects evolve to a first clinical symptom, and an age <37 y, male sex, and spinal cord involvement appear to be the most important independent predictors of symptom onset.
Abstract: Objective
To report the 5-year risk and to identify risk factors for the development of a seminal acute or progressive clinical event in a multi-national cohort of asymptomatic subjects meeting 2009 RIS Criteria.
241 citations
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TL;DR: A large-scale survey of genomic nucleotide composition across monocots has enabled the first rigorous testing, to the authors' knowledge, of its biological significance in plants, and shows that genomic DNA base composition (GC content) is significantly associated with genome size and holocentric chromosomal structure.
Abstract: Genomic DNA base composition (GC content) is predicted to significantly affect genome functioning and species ecology. Although several hypotheses have been put forward to address the biological impact of GC content variation in microbial and vertebrate organisms, the biological significance of GC content diversity in plants remains unclear because of a lack of sufficiently robust genomic data. Using flow cytometry, we report genomic GC contents for 239 species representing 70 of 78 monocot families and compare them with genomic characters, a suite of life history traits and climatic niche data using phylogeny-based statistics. GC content of monocots varied between 33.6% and 48.9%, with several groups exceeding the GC content known for any other vascular plant group, highlighting their unusual genome architecture and organization. GC content showed a quadratic relationship with genome size, with the decreases in GC content in larger genomes possibly being a consequence of the higher biochemical costs of GC base synthesis. Dramatic decreases in GC content were observed in species with holocentric chromosomes, whereas increased GC content was documented in species able to grow in seasonally cold and/or dry climates, possibly indicating an advantage of GC-rich DNA during cell freezing and desiccation. We also show that genomic adaptations associated with changing GC content might have played a significant role in the evolution of the Earth’s contemporary biota, such as the rise of grass-dominated biomes during the mid-Tertiary. One of the major selective advantages of GC-rich DNA is hypothesized to be facilitating more complex gene regulation.
241 citations
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TL;DR: Addition of CMLVAX100 to conventional treatment in patients with chronic myeloid leukaemia might favour further reduction of residual disease and increase the number of patients reaching a molecular response.
240 citations
Authors
Showing all 12352 results
Name | H-index | Papers | Citations |
---|---|---|---|
Johan Auwerx | 158 | 653 | 95779 |
I. V. Gorelov | 139 | 1916 | 103133 |
Roberto Tenchini | 133 | 1390 | 94541 |
Francesco Fabozzi | 133 | 1561 | 93364 |
M. Davier | 132 | 1449 | 107642 |
Roberto Dell'Orso | 132 | 1412 | 92792 |
Rino Rappuoli | 132 | 816 | 64660 |
Teimuraz Lomtadze | 129 | 893 | 80314 |
Manas Maity | 129 | 1309 | 87465 |
Dezso Horvath | 128 | 1283 | 88111 |
Paolo Azzurri | 126 | 1058 | 81651 |
Vincenzo Di Marzo | 126 | 659 | 60240 |
Igor Katkov | 125 | 972 | 71845 |
Ying Lu | 123 | 708 | 62645 |
Thomas Schwarz | 123 | 701 | 54560 |