Institution
Weizmann Institute of Science
Education•Rehovot, Israel•
About: Weizmann Institute of Science is a education organization based out in Rehovot, Israel. It is known for research contribution in the topics: Population & Gene. The organization has 21942 authors who have published 54561 publications receiving 3032812 citations. The organization is also known as: Bessie F. Lawrence International Summer Science Institute & Weitzman Institute.
Topics: Population, Gene, Antigen, Receptor, Immune system
Papers published on a yearly basis
Papers
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California Institute of Technology1, Carnegie Learning2, National Central University3, University of Michigan4, Goddard Space Flight Center5, University of Maryland, College Park6, Northwestern University7, Adler Planetarium8, University of Washington9, Weizmann Institute of Science10, University of California, Santa Barbara11, University of Wisconsin–Milwaukee12
TL;DR: The Zwicky Transient Facility (ZTF) as mentioned in this paper is a robotic time-domain survey currently in progress using the Palomar 48-inch Schmidt Telescope, which uses a 600 megapixel camera to scan the entire northern visible sky at rates of ~3760 square degrees/hour.
Abstract: The Zwicky Transient Facility (ZTF) is a new robotic time-domain survey currently in progress using the Palomar 48-inch Schmidt Telescope. ZTF uses a 47 square degree field with a 600 megapixel camera to scan the entire northern visible sky at rates of ~3760 square degrees/hour to median depths of g ~ 20.8 and r ~ 20.6 mag (AB, 5σ in 30 sec). We describe the Science Data System that is housed at IPAC, Caltech. This comprises the data-processing pipelines, alert production system, data archive, and user interfaces for accessing and analyzing the products. The real-time pipeline employs a novel image-differencing algorithm, optimized for the detection of point-source transient events. These events are vetted for reliability using a machine-learned classifier and combined with contextual information to generate data-rich alert packets. The packets become available for distribution typically within 13 minutes (95th percentile) of observation. Detected events are also linked to generate candidate moving-object tracks using a novel algorithm. Objects that move fast enough to streak in the individual exposures are also extracted and vetted. We present some preliminary results of the calibration performance delivered by the real-time pipeline. The reconstructed astrometric accuracy per science image with respect to Gaia DR1 is typically 45 to 85 milliarcsec. This is the RMS per-axis on the sky for sources extracted with photometric S/N ≥ 10 and hence corresponds to the typical astrometric uncertainty down to this limit. The derived photometric precision (repeatability) at bright unsaturated fluxes varies between 8 and 25 millimag. The high end of these ranges corresponds to an airmass approaching ~2—the limit of the public survey. Photometric calibration accuracy with respect to Pan-STARRS1 is generally better than 2%. The products support a broad range of scientific applications: fast and young supernovae; rare flux transients; variable stars; eclipsing binaries; variability from active galactic nuclei; counterparts to gravitational wave sources; a more complete census of Type Ia supernovae; and solar-system objects.
453 citations
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TL;DR: In this Review, Kolodziejczyk, Zheng and Elinav describe the latest advances in understanding diet–microbiota interactions, the individuality of gut microbiota composition and how this knowledge could be harnessed for personalized nutrition strategies to improve human health.
Abstract: Conceptual scientific and medical advances have led to a recent realization that there may be no single, one-size-fits-all diet and that differential human responses to dietary inputs may rather be driven by unique and quantifiable host and microbiome features. Integration of these person-specific host and microbiome readouts into actionable modules may complement traditional food measurement approaches in devising diets that are of benefit to the individual. Although many host-derived factors are hardwired and difficult to modulate, the microbiome may be more readily reshaped by environmental factors such as dietary exposures and is increasingly recognized to potentially impact human physiology by participating in digestion, the absorption of nutrients, shaping of the mucosal immune response and the synthesis or modulation of a plethora of potentially bioactive compounds. Thus, diet-induced microbiota alterations may be harnessed in order to induce changes in host physiology, including disease development and progression. However, major limitations in ‘big-data’ processing and analysis still limit our interpretive and translational capabilities concerning these person-specific host, microbiome and diet interactions. In this Review, we describe the latest advances in understanding diet–microbiota interactions, the individuality of gut microbiota composition and how this knowledge could be harnessed for personalized nutrition strategies to improve human health. In this Review, Kolodziejczyk, Zheng and Elinav describe the latest advances in understanding diet–microbiota interactions, the individuality of gut microbiota composition and how this knowledge could be harnessed for personalized nutrition strategies to improve human health.
453 citations
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TL;DR: This review summarizes typical structures of perovskite solar cells and comments on novel device structures, and the applications of perOVskiteSolar cells are discussed.
Abstract: Organolead halide perovskite materials possess a combination of remarkable optoelectronic properties, such as steep optical absorption edge and high absorption coefficients, long charge carrier diffusion lengths and lifetimes. Taken together with the ability for low temperature preparation, also from solution, perovskite-based devices, especially photovoltaic (PV) cells have been studied intensively, with remarkable progress in performance, over the past few years. The combination of high efficiency, low cost and additional (non-PV) applications provides great potential for commercialization. Performance and applications of perovskite solar cells often correlate with their device structures. Many innovative device structures were developed, aiming at large-scale fabrication, reducing fabrication cost, enhancing the power conversion efficiency and thus broadening potential future applications. This review summarizes typical structures of perovskite solar cells and comments on novel device structures. The applications of perovskite solar cells are discussed.
453 citations
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TL;DR: The synaptic enzyme acetylcholinesterase is the target of nerve agents, insecticides and therapeutic drugs, in particular the first generation of anti-Alzheimer drugs, and is believed to play 'non-classical' roles in addition to its ' classical' role in terminating synaptic transmission.
453 citations
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TL;DR: It is shown analytically that for noisy expression data the proposed approach leads to better classification due to the implementation of the threshold, and argues that the method is in fact a generalization of singular value decomposition, which corresponds to the special case where no threshold is applied.
Abstract: We present an approach for the analysis of genome-wide expression data. Our method is designed to overcome the limitations of traditional techniques, when applied to large-scale data. Rather than alloting each gene to a single cluster, we assign both genes and conditions to context-dependent and potentially overlapping transcription modules. We provide a rigorous definition of a transcription module as the object to be retrieved from the expression data. An efficient algorithm, which searches for the modules encoded in the data by iteratively refining sets of genes and conditions until they match this definition, is established. Each iteration involves a linear map, induced by the normalized expression matrix, followed by the application of a threshold function. We argue that our method is in fact a generalization of singular value decomposition, which corresponds to the special case where no threshold is applied. We show analytically that for noisy expression data our approach leads to better classification due to the implementation of the threshold. This result is confirmed by numerical analyses based on in silico expression data. We discuss briefly results obtained by applying our algorithm to expression data from the yeast Saccharomyces cerevisiae.
453 citations
Authors
Showing all 22106 results
Name | H-index | Papers | Citations |
---|---|---|---|
Lewis C. Cantley | 196 | 748 | 169037 |
Chris Sander | 178 | 713 | 233287 |
David A. Weitz | 178 | 1038 | 114182 |
Michael I. Jordan | 176 | 1016 | 216204 |
Richard H. Friend | 169 | 1182 | 140032 |
Yang Yang | 164 | 2704 | 144071 |
Aviv Regev | 163 | 640 | 133857 |
Dongyuan Zhao | 160 | 872 | 106451 |
Tobin J. Marks | 159 | 1621 | 111604 |
Klaus Rajewsky | 154 | 504 | 88793 |
Roberto Romero | 151 | 1516 | 108321 |
Rui Zhang | 151 | 2625 | 107917 |
Joseph Schlessinger | 150 | 492 | 98862 |
Mikhail D. Lukin | 146 | 606 | 81034 |
Danny Reinberg | 145 | 342 | 68201 |