Yahoo!

About: Yahoo! is a company organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Web search query. The organization has 26749 authors who have published 29915 publications receiving 732583 citations. The organization is also known as: Yahoo! Inc. & Maudwen-Yahoo! Inc.

Automatic advertiser notification for a system for providing place and price protection in a search result list generated by a computer network search engine

Abstract: A notification method in a computer database system includes receiving a notification instruction from an owner associated with a search listing stored in the computer database system, monitoring conditions specified by the notification instruction for the search listing, and sending a notification to the owner upon detection of a changed condition of the search listing.

Total Phenolic Contents and Antioxidant Capacities of Selected Chinese Medicinal Plants

Abstract: Antioxidant capacities of 56 selected Chinese medicinal plants were evaluated using the Trolox equivalent antioxidant capacity (TEAC) and ferric reducing antioxidant power (FRAP) assays, and their total phenolic content was measured by the Folin-Ciocalteu method. The strong correlation between TEAC value and FRAP value suggested that the antioxidants in these plants possess free radical scavenging activity and oxidant reducing power, and the high positive correlation between antioxidant capacities and total phenolic content implied that phenolic compounds are a major contributor to the antioxidant activity of these plants. The results showed that Dioscorea bulbifera, Eriobotrya japonica, Tussilago farfara and Ephedra sinica could be potential rich sources of natural antioxidants.

k-nearest neighbors in uncertain graphs

Abstract: Complex networks, such as biological, social, and communication networks, often entail uncertainty, and thus, can be modeled as probabilistic graphs. Similar to the problem of similarity search in standard graphs, a fundamental problem for probabilistic graphs is to efficiently answer k-nearest neighbor queries (k-NN), which is the problem of computing the k closest nodes to some specific node.In this paper we introduce a framework for processing k-NN queries in probabilistic graphs. We propose novel distance functions that extend well-known graph concepts, such as shortest paths. In order to compute them in probabilistic graphs, we design algorithms based on sampling. During k-NN query processing we efficiently prune the search space using novel techniques.Our experiments indicate that our distance functions outperform previously used alternatives in identifying true neighbors in real-world biological data. We also demonstrate that our algorithms scale for graphs with tens of millions of edges.

Canaloplasty: Circumferential viscodilation and tensioning of Schlemm canal using a flexible microcatheter for the treatment of open-angle glaucoma in adults Two-year interim clinical study results

Abstract: Purpose To evaluate the safety and efficacy of circumferential viscodilation and tensioning of the inner wall of Schlemm's canal in a new surgical procedure for the treatment of open-angle glaucoma (OAG). Setting Fourteen clinical sites in the United States and Germany. Methods In this international multicenter prospective study of adult patients with OAG having glaucoma surgery, patients with qualifying preoperative intraocular pressure (IOP) of at least 16 mm Hg or higher and open angles were eligible. Evaluation was performed at baseline and 1 day, 1 week, and 1, 3, 6, and 12 months preoperatively. After a nonpenetrating dissection technique to expose Schlemm's canal was performed, a flexible microcatheter (iTrack 250A, iScience Interventional) was used to dilate the full circumference of the canal by injecting sodium hyaluronate 1.4% (Healon GV) during catheterization. A suture loop was placed in the canal to apply tension to the trabecular meshwork. High-resolution ultrasound imaging was used to assess Schlemm's canal and anterior segment angle morphology, including distension of the trabecular meshwork caused by the tensioning suture. Data analysis was performed in 2 groups: Group 1, in which patients met all inclusion criteria, and Group 2, made up of Group 1 patients who had successful suture placement. Results Group 1 comprised 94 patients and Group 2, 74 patients. The mean baseline IOP in Group 1 was 24.7 mm Hg ± 4.8 (SD) on a mean of 1.9 ± 1.0 medications per patient. In Group 2 (patients with sutures), the mean IOP was 16.1 ± 4.7 mm Hg 3 months postoperatively, 15.6 ± 4.0 mm Hg at 6 months, and 15.3 ± 3.8 mm Hg at 1 year. Medication use dropped to a mean of 0.6 ± 0.9 per patient at 12 months. Suture tensioning was an apparent contributing factor in achieving surgical success. Patients with measurable trabecular meshwork distension from suture tension had a mean IOP of 15.9 ± 5.2 mm Hg at 6 months and 14.5 ± 3.0 mm Hg at 12 months. Surgical and postsurgical adverse events were reported in 15 of 94 patients (16%) and included hyphema (3), elevated IOP greater than 30 mm Hg (3), Descemet's tear (1), hypotony (1), choroidal effusion (1), and exposed closure suture with eyelid edema and erythema epiphora (1); 4 patients were subsequently converted to trabeculectomy. Conclusion Circumferential viscodilation and tensioning of Schlemm's canal was a safe and effective surgical procedure to reduce IOP in adult patients with OAG.

Review on leptin and adiponectin responses and adaptations to acute and chronic exercise

Abstract: Leptin and adiponectin represent two newly discovered adipose tissue derived hormones; that are both associated with health status and glucose and free fatty acid (FFA) metabolism. Moreover, acute and chronic exercises affect body composition, carbohydrate and lipid metabolism. It is thus interesting to evaluate the effects of physical exercise and training on leptin and adiponectin levels. It seems that leptin concentration is not modified after short-term exercise ( or =60 min) stimulating FFA release, or after exercise that generates energy expenditure higher than 800 kcal. Adiponectin concentration presents a delayed increase (30 min) after short-term intense exercise ( or =60 min). Short-term training ( or =12 weeks) show contrasting results regarding leptin and adiponectin. Most training studies which improve fitness levels and affect body composition could decrease leptin and increase adiponectin concentrations.