Showing papers in "Endocrine Practice in 2019"

TL;DR: Looking AHEAD = Look Action for Health in Diabetes means taking action to control Cardiovascular Risk in Diabetes Blood pressure and looking at potential barriers to this action.

TL;DR: These updated clinical practice guidelines for bariatric procedures remain a safe and effective intervention for higher-risk patients with obesity and clinical decision-making should be evidence-based within the context of a chronic disease.

TL;DR: This update summarizes the most current knowledge about the accuracy of available GH-stimulation tests, safety of recombinant human GH (rhGH) replacement, unapproved uses of rhGH related to sports and aging, and new developments such as long-acting GH preparations that use a variety of technologies to prolong GH action.

TL;DR: The GSC data suggest that the GSC further reduces surgery in indeterminate thyroid nodules by improving the specificity of Afirma technology without compromising sensitivity.

TL;DR: IAH is highly prevalent and is related to a higher risk for severe hypoglycemia in T1D patients using CGM, and is associated with a longer duration of CGM glucose and higher glucose coefficients of variation.

TL;DR: A case-based clinical approach to the evaluation of incidentally discovered adrenal masses is presented in this article, where the role of biopsy, surgical or medical therapy, and longitudinal surveillance are also important to consider.

TL;DR: The ATA and TI-RADS classification systems appear to have similar diagnostic value for predicting thyroid cancer, however, subanalysis of TR3 and TR4 nodules with consideration of size criteria showed that there is a higher risk of missing a malignancy if the ACR TI- RADS recommendation is followed.

TL;DR: Using either the ATA or the TI-RADS system to risk-stratify nodules with indeterminate cytology may help clinicians plan better for additional diagnostic testing and treatment.

TL;DR: This decision tree employs three validated predictive markers and other clinical considerations, to determine whether SSAs are appropriate first-line medical therapy in the postsurgical setting, and proposes a decision tree to guide selection among SSAs, dopamine agonists (DAs), and GHRA for medical treatment of acromegaly in the Postsurgical setting.

TL;DR: Improved long-term outcomes were associated with younger age, lower tumor stage, no extrathyroidal extension, bone-only metastases, and non-spinal BM, which were the only independent predictors for improved survival.

TL;DR: Most patients with giant prolactinoma have excellent response to DA and sex, age, initial PRL, tumor size, or first-line therapy mode do not predict therapeutic response.

TL;DR: Thyroid dysfunction following treatment with PD-1 inhibitors is common, and patients with a higher baseline TSH appear to be at increased risk, and such patients may benefit from closer monitoring of their thyroid function following initiation of anti-programmed cell death 1 agents.

TL;DR: The results suggest that BPs may suppress high bone turnover to partially control the activity of the disease and are well tolerated in most patients.

TL;DR: The decrease in ROM was confirmed for most of TBSRTC categories, which was more significant in Western than in Asian practice, and the incidence of NIFTP was higher in institutions where surgical resection rates were high in patients with indeterminate cytology nodules.

TL;DR: This study is the first showing that thyroid nodules located in the upper pole can be considered as having higher risk for malignancy, and it may enhance the predictive value of malignancies if it is included in thyroid nodule ultrasound classification guidelines.

TL;DR: Real-world implementation of HCL technology using a structured education program within a major medical center demonstrates improved glycemic control with hybrid close loop (HCL) insulin delivery systems, yet limited real-world data exists.

TL;DR: A core set of recommendations to culturally adapt diabetes care is presented that emphasizes culturally appropriate terminology, transculturalization of white papers, culturally adapting clinic infrastructure, flexible office hours, and more funding for scientific studies on epigenetic mechanisms of cultural impact on disease expression.

TL;DR: Diagnosis currently must be inferred from co-morbidities, but ultimately should be made by imaging once the importance of fatty kidney disease is established, much like fatty liver disease.

TL;DR: Dysfunctional brain homology may reveal the pathological mechanisms underlying the visual pathways of patients with diabetic retinopathy using regional homogeneity (ReHo) to explore neural homogeneity in the brain.

TL;DR: Thyroid cancer information is widely available online, but quality varies: sites often lack markers for patients to assess quality, and content may be difficult to understand.

TL;DR: TSH suppression before the first response to treatment assessment does not appear to influence the rate of structural disease evaluated 1 and 3 years after primary treatment.

TL;DR: Underweight was associated with a lower prevalence of hyperuricemia in men aged ≤69 years and in women aged 20 to 29 years, respectively, and in individuals with overweight or obesity, younger subjects were more likely to develop hyperuricaemia than older subjects.

TL;DR: The results show that hypoglycemia occurs not only postprandially but also in the fasting state, especially following bypass procedures, possibly leading to its underestimation.

TL;DR: Lower serum 25(OH)D concentration is significantly associated with increased ACR and higher prevalence of DR in middle-aged and elderly diabetic adults in Chinese diabetic adults, suggesting the possibility of a causal relationship between 25( OH)D deficiency and diabetic microvascular complications remains to be demonstrated.

TL;DR: A systematic review and meta-analysis demonstrates a statistically significant increased risk of multifocality/multicentricity and distant metastasis at the time of cancer diagnosis in DTC patients with GD than those without GD.

TL;DR: The majority of PC patients have a relatively long survival with multiple recurrences, and the main factor influencing PC outcomes may be the biological characteristics rather than the surgical extent.

TL;DR: Reducing total body adiposity and triglyceride levels, as well as avoiding leg subcutaneous fat atrophy, could be new prevention strategies for DPN in Chinese patients with type 2 diabetes mellitus.

TL;DR: In this case series of pregnant patients with primary hyperparathyroidism during pregnancy, the most common complaint of GIT symptoms may be easily confused with pregnancy reactions, which might contribute to the under- or misdiagnosis of this clinical entity.

TL;DR: Acute weight loss may be more important for T2DM glycemic control following both RYGB and SG as compared with weight regain and clinicians should aim to assist patients with achieving maximal weight loss in the first year post op to maximize long-term health of patients.

TL;DR: Differentiated thyroid cancer (DTC), the most common subtype of thyroid cancer, has a relatively good prognosis and could be further stratified by T stage, which was an independent prognostic factor for both OS and CSS in multivariate analysis.