Showing papers in "Legal Medicine in 2018"

TL;DR: The Willems method was the most accurate for estimating a dental age if all seven mandibular teeth are available for analysis, and the similar accuracy of Dem76PM1 and Dem76IN2 methods were found, which may encourage their use for age estimation on the Kosovar children.

TL;DR: The suggested value of I3M < 0.08 followed by Nolla stage 9 can be used to discriminate adults from minors with high specificity and is verified.

TL;DR: A preliminary 8-marker system for BFID including an endogenous reference gene and a linear primer system to incorporate additional miRNA markers by forming a multiplex system was designed and was able to distinguish between venous blood, menstrual blood, semen, and saliva.

TL;DR: Signs are provided that the sacrum and coccyx are important bones for sex estimation and they could be effectively used as alternatives in forensic cases when the skull and pelvis are unavailable and the regression equations presented in this study may be useful for forensic estimation of the stature of Chinese individuals.

TL;DR: In this article, an age-predictive method based on DNA-methylation patterns in semen was developed, using three CpG sites (cg06304190 in the TTC7B gene, cg12837463, and cg06979108 in the NOX4 gene).

TL;DR: There is justification for the use of differing or multiple assumptions on the NOC when computing the weight of DNA evidence for low-template mixtures, particularly when the peak heights are in the vicinity of the signal threshold or allele counting methods are the mechanism by which the Noc is assessed.

TL;DR: This is the first study to establish an OSC-PLS regression model for predicting PMI with the metabolome, which provides a new technical method and platform for estimating PMI through metabolomics.

TL;DR: The present study has highlighted the importance of extending research to whole skeletons without focusing only on single bones, in order to have a better understanding of the histomorphological variability of both human and non-human bone.

TL;DR: Medicolegal experts finally have determined that the cause of death was fatal intoxication with the main role of PV8, another synthetic cathinone which is dangerous for live of the users and requires constant monitoring and further research.

TL;DR: This high-throughput method was developed for analysis of valproate in human plasma samples by QuEChERS extraction and gas chromatography-tandem mass spectrometry (GC-MS/MS) and successfully applied to actual analyses of an autopsy case.

TL;DR: Oral and maxillofacial traumas are very common among women victims of IPV who searched for medical-legal service and should always work together with medical, biochemical and toxicological experts.

TL;DR: The measurements of FM do not offer sufficiently high predicting rates for sex estimation in the Bulgarian population and the eigenvalue λ3 is the best discriminating parameter applying discriminant function analysis.

TL;DR: The concentrations of EAM-2201 in authentic human specimens including blood and solid tissues and those of AB-PINACA and AB-FUBINACA in solid tissue specimens were quantified for the first time to the authors' knowledge.

TL;DR: Results support miRNAs as an innovative class of biomarkers compatible with an adequate analysis of biospecimens obtained from forensic autopsies.

TL;DR: The accuracies of the original DemirJian, modified Demirjian and Willems dental age estimation methods were compared for a Black Southern African population to determine their usefulness for forensic and anthropological purposes.

TL;DR: A 60-locus SNP assay designed for the differentiation of Japanese people from other East Asians using entirely and nearly Japanese-specific alleles was developed, which was named Japaneseplex.

TL;DR: A case of female body packer using multiple modalities of concealment especially in vagina is rare in India so it is becomes imperative to present this case in the light of body packing and body pushing of contraband substances.

TL;DR: A review of the cases of toluene abuse and intoxication and the state of the art of the forensic toxicological analysis of toLUene intoxications in the living and in the dead subject is provided, from the early identification to the medico-legal interpretation of the toxicological result.

TL;DR: While both STR kits showed a decrease in alleles as the inhibitor concentration increased, more complete profiles were obtained when the Investigator®, kit was used, and the data suggest that the GlobalFiler® kit may be slightly more sensitive than the Investigator® kit.

TL;DR: The results suggest that, under favorable conditions, the luminol technique can detect haemoglobin in the bone in a PMI range of 0-65 years, and the conclusion is that this quantitative, objective and contrastable technique could be very useful for determining the PMI in bone remains.

TL;DR: The results indicate that SYBR qPCR is an effective method for age estimation from bloodstains, and its practicality and affordability make it an attractive sjTREC quantification technique.

TL;DR: A technique based on replacement of heavily damaged hard tissues with generic prosthetics manufactured by 3D printing is proposed, which is simple, affordable and relatively labor-efficient.

TL;DR: A highly sensitive method was developed for the analysis of alendronate in human plasma and dialysate using MonoSpin™ SAX® extraction and metal-free high-performance liquid chromatography (HPLC)-tandem mass spectrometry (MS/MS) following methylation with trimethylsilyldiazomethane.

TL;DR: This study is the first comprehensive investigation of the effect of SNPs in genes encoding zinc transporters on blood zinc concentration in Japanese subjects and finds combination of SLC30A3 rs11126936 and SLC39A8 rs233804 may strongly affect blood zinc levels.

TL;DR: This work provided new leads for molecular approaches to early postmortem interval estimation using the significant mRNA markers established here, and Rpl27 was found to be suitable for use as the endogenous control.

TL;DR: The results reported by the authors are consistent with massive gas embolism similar to changes presented in cases of decompression illness, and they suggest this as the cause of death in helium inhalation cases.

TL;DR: This method was designed to identify nine domestic animals simultaneously and four wild animals by comparing the different melting temperatures of the amplicons produced from samples originating from each species by using two multiplex real-time PCRs and analysis of the resultant SYBR Green I melting curves.

TL;DR: Results from the collection of previous reports show that null alleles at D5S818 were frequently observed in population detected by two PowerPlex® typing systems and null allels at D19S433 were mostly observed in Japanese population observed by two AmpFℓSTR™ typing systems.

TL;DR: The RM Y-STRs and PowerPlex® Y23 System and AmpFℓSTR® Yfiler™ kit were analyzed in 216 male relatives from 18 deep rooted endogamous Sindhi families from Pakistan indicating the considerable power in paternal lineage differentiation in endogamy populations.

TL;DR: A 35-year-old man presented with behavioral disturbances of sudden onset after oral cannabis consumption and major self-mutilation which resulted in death which was related to hemorrhage following the mutilations.