Showing papers in "The Journal of Pediatrics in 2011"
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TL;DR: A 12-year-old boy currently is followed by multiple sub-specialists for problems caused by the chromosome 22q11.2 deletion syndrome (22q11DS) and has mild dysmorphic facial features of a boy aged 11 years with 22q 11.2DS.
483 citations
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TL;DR: In this article, the outcomes after prolonged empirical antibiotic administration to premature infants in the first week of life were investigated, and concluding subsequent late onset sepsis (LOS), necrotizing enterocolitis (NEC), and death.
464 citations
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TL;DR: In this article, the authors examined tracking and predictiveness of childhood lipid levels, blood pressure, and body mass index for risk profile in adulthood and the best age to measure the childhood risk factor levels.
430 citations
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TL;DR: Language ability is reduced in VPT/VLBW children, and when considering only school-aged children, this reduction is still present, suggesting that their difficulty appears to be ongoing.
310 citations
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TL;DR: In this paper, the duration of antibiotic exposure is associated with an increased risk of necrotizing enterocolitis among infants without prior sepsis, while exposure for >10 days resulted in a nearly threefold increase in the risk of developing NEC.
307 citations
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TL;DR: Primary steroid therapy did not improve coronary outcomes in patients prospectively classified as being at high-risk for IVIG resistance, and risk-scoring systems from Japan have good specificity but low sensitivity for predictingIVIG resistance in a North American cohort.
303 citations
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TL;DR: HRC monitoring can reduce the mortality rate in very low birth weight infants and there was a trend toward increased days alive and ventilator-free in the 120 days after randomization.
299 citations
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TL;DR: The Beighton score, when goniometry is used, is a valid instrument to measure generalized joint mobility in school-age children 6 to 12 years and no extra items are needed to improve the scale.
299 citations
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TL;DR: In this paper, the feasibility of implementing a broadband screen at the 1-year check-up to detect cases of autism spectrum disorders (ASD), language delay (LD), and developmental delay (DD) was evaluated.
228 citations
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TL;DR: Microflora diversity settled progressively in very preterm infants and was associated with the digestive tolerance profile, and measures that may improve microflora could have beneficial effects on digestive tolerance and growth.
202 citations
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TL;DR: It is concluded that PRBC-related NEC exists and the convergence at 31 weeks postconceptual age approximates the age of presentation of other O(2) delivery and neovascularization syndromes, suggesting a link to a generalized systemic maturational mechanism.
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TL;DR: It is suggested that although hypothermia is unequivocally a promising therapy for HIE, a substantial proportion of infants still suffer from death or disability despite treatment, and should lead to an overall measure of caution in applying the new therapy of hypotheria indiscriminately for all cases of HIE.
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TL;DR: The results indicate that hypovitaminosis D is frequent in children with asthma living in a Mediterranean country and in those children, lower levels of vitamin D are associated with reduced asthma control.
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TL;DR: Altered postnatal fatty acid levels in premature infants are associated with an increased risk of chronic lung disease (CLD) and late-onset sepsis.
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TL;DR: Plasma and urine NGAL thresholds significantly increased in patients with AKI at 2 hours after CPB and remained elevated at all points, with 2-hour NGAL the earliest, strongest predictor of AKI.
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TL;DR: Preschoolers' cumulative screen time exceeds recommendations and most previous estimates and Efforts to decrease screen time in homes and home-based child care settings are needed.
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TL;DR: Hospitalized patients who used a structured clinical program for children with medical complexity experienced lengthy hospitalizations with high early readmission rates, and reducing hospital readmission may be one potential strategy for decreasing inpatient expenditures in this group of children with high resource utilization.
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TL;DR: Renal function and serum troughs in children receiving vancomycin, especially those with targeted troughs of ≥ 15 mg/L, in intensive care, and receiving furosemide, should be closely monitored.
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TL;DR: CP incidence and severity decreased from 1990-1993 onward, which could be attributed to a reduction of 93% in severe c-PVL.
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TL;DR: The primary reliance on serum food-specific IgE testing to determine the need for a food elimination diet is not sufficient, especially in children with atopic dermatitis, and oral food challenges may be indicated to confirm food allergy status.
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TL;DR: It is demonstrated that race and sex differences in telomere length have already emerged during adolescence, adiposity and adipokines are not associated with telomeres length at this age, and the antiaging effect of vigorous physical activity may begin in youth, especially in girls.
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TL;DR: Patients with IVig-resistant Kawasaki disease whose first re-treatment was with infliximab, compared with IVIG, had faster resolution of fever and fewer days of hospitalization.
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TL;DR: Both moderate and early preterm infants had more frequent problems with fine motor, communication, and personal-social functioning compared with full-term infants, and Socioeconomic status, small for gestational age status, and sex were associated with abnormal ASQ scores in moderate pre term infants.
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TL;DR: In healthy adolescent males and females, bone mass and bone density at skeletal maturity are inversely related to the timing of puberty, as observed in the Bone Mineral Density in Childhood Study.
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TL;DR: ALF in young infants presents unique diagnostic considerations and spontaneous survival is better than previously thought, and Liver transplantation provides an additional option for care.
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TL;DR: Exposure to maternal diabetes in utero accelerates BMI growth in late childhood, thus increasing long-term obesity risk, according to a diverse cohort of youth.
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TL;DR: Hypocarbia is associated with poor outcome after hypoxic-ischemic encephalopathy, and death/disability increased with greater cumulative exposure to PCO(2) <35 mm Hg.
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TL;DR: Shorter and longer sleep durations are associated with decreased insulin sensitivity in adolescents, and the association between shorter sleep duration and HOMA was appreciably attenuated, but the association with longer sleep persisted.
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TL;DR: ACS exposure improved survival of extremely preterm infants and should be considered for threatened preterm birth at 22 to 23 weeks of gestation.
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TL;DR: In long-term follow-up, most patients with PFAPA experienced spontaneous symptom resolution without sequelae, and patients with persistent symptoms had episodes of shorter duration and reduced frequency.