Journal ArticleDOI
184: DUSP11 is a critical regulator of innate immune responses mediated by dendritic cells
Kalyan C. Nallaparaju,Kalyan C. Nallaparaju,Yongliang Zhang,Xikui Liu,Joseph M. Reynolds,Roza Nurieva,Roza Nurieva,Chen Dong,Chen Dong +8 more
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TLDR
In vivo experiments demonstrated that DUSP11 deficient mice are defective in antigen-specific T cell responses and that they are more susceptible to Listeria monocytogenes infection, which supports the growing body of evidence that intrinsic pathways in innate immune cells can modulate T cell lineage differentiation.About:
This article is published in Cytokine.The article was published on 2013-09-01. It has received 1 citations till now. The article focuses on the topics: Dendritic cell & T cell.read more
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Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases.
TL;DR: Recent findings describing the roles of dual-specificity phosphatases in neurodegeneration are summarized and perspectives on future therapeutic directions are offered.