Proceedings ArticleDOI
A bidirectional neural interface featuring a tunable recorder and electrode impedance estimation
Michael Haas,Jens Anders,Maurits Ortmanns +2 more
- pp 372-375
TLDR
An improved, bi-directional neural interface with a tunable lower cut-off frequency and an online electrode impedance estimation and the parameters of a simplified electrode model can be calculated, with a simulated accuracy of ±15%.Abstract:
This paper presents an improved, bi-directional neural interface with a tunable lower cut-off frequency and an online electrode impedance estimation. Each channel features a low voltage (LV) recorder and a high voltage (HV) stimulator, separated by a HV protection network. The recorder utilizes a 3-Bit switched capacitor (SC), serial DAC to adjust the resistance of a MOS-bipolar pseudo-resistor in the neural recorder. Thereby, its lower cut-off frequency can be adjusted between 15mHz and 70 Hz, with a logarithmic scaling. Additionally a low-gain mode is implemented which together with the HV stimulator allows for an estimation of the electrode impulse response. From this impulse response the parameters of a simplified electrode model can be calculated, with a simulated accuracy of ±15%. A single channel prototype has been layouted and is currently manufactured in a 180 nm HV CMOS technology. The prototype occupies an area of 715 μm × 580 μm. It has a simulated power consumption of 58 μW per channel of which 11 μW are consumed in the tunable Low Noise Amplifier (LNA). The simulated, input referred noise of the LNA ranges between 3.2 μVrms (70 Hz–7.5 kHz) and 4.5 μVrms (0.1 Hz–7.5 kHz) depending on the adjusted value of the lower cut-off frequency.read more
Citations
More filters
Journal ArticleDOI
A High-Voltage Compliance, 32-Channel Digitally Interfaced Neuromodulation System on Chip
TL;DR: The developed system constitutes a fully digital, bidirectional 32-channel interface to the brain and offers low-noise recording, a state-of-the-art neurostimulator capable of both current- and voltage-controlled stimulation with high-voltage compliance, on-chip 16-bit data digitization as well as safety features such as electrode impedance estimation and charge balancing.
Journal ArticleDOI
A Neuromodulator Frontend With Reconfigurable Class-B Current and Voltage Controlled Stimulator
TL;DR: In this article, a reconfigurable current and voltage mode stimulator for a bidirectional, neural interface is presented, which can deliver up to ±10 mA of output current and ±6 V of stimulation voltage.
Journal ArticleDOI
A Dynamic Power Reduction Technique for Incremental $\Delta\Sigma$ Modulators
TL;DR: In this article, the authors proposed a dynamic power reduction technique for incremental I-Sigma modulators, which makes use of the unequal weighting of the higher order reconstruction filter, which can increase the non-idealities of the modulator during the runtime of a single Nyquist conversion, thereby saving power.
Proceedings ArticleDOI
FIR DACs in CT Incremental Delta-Sigma Modulators
TL;DR: This paper describes the challenges that come with acquiring an FIR DAC in an incremental ΔΣ modulator and two design techniques are shown to mitigate the swing overshoots and achieve a normal operation of the modulator.
Journal ArticleDOI
A 14b, Twofold Time-Interleaved Incremental ΔΣ ADC Using Hardware Sharing
TL;DR: The presented proof-of-concept design makes use of time interleaving two third-order I- modulators with embedded hardware sharing that helps to enhance the efficiency of the presented modulator.
References
More filters
Journal ArticleDOI
A low-power low-noise CMOS amplifier for neural recording applications
R.R. Harrison,C.T. Charles +1 more
TL;DR: In this article, a low-noise low-power biosignal amplifiers capable of amplifying signals in the millihertz-to-kilohertz range while rejecting large dc offsets generated at the electrode-tissue interface is presented.
Proceedings ArticleDOI
A low-power, low-noise CMOS amplifier for neural recording applications
TL;DR: A novel bioamplifier that uses a MOS-bipolar pseudo-resistor to amplify signals down to the mHz range while rejecting large dc offsets and it is demonstrated that the VLSI implementation approaches the theoretical noise-power tradeoff limit.
Journal ArticleDOI
A Battery-Powered Activity-Dependent Intracortical Microstimulation IC for Brain-Machine-Brain Interface
TL;DR: An activity-dependent intracortical microstimulation (ICMS) system-on-chip (SoC) that converts extracellular neural spikes recorded from one brain region to electrical stimuli delivered to another brain region in real time in vivo is described.
Journal ArticleDOI
Implementing Ultra-high-Value Floating Tunable CMOS Resistors
TL;DR: In this paper, a compact high-value resistor utilising PMOS devices in the subthreshold region is introduced, and a test chip has been fabricated in 0.18 um CMOS technology to verify the proposed concept.
Journal ArticleDOI
320-Channel Active Probe for High-Resolution Neuromonitoring and Responsive Neurostimulation
R. Shulyzki,Karim Abdelhalim,Arezu Bagheri,M. Tariqus Salam,Carlos M. Florez,Jose Luis Perez Velazquez,Peter L. Carlen,Roman Genov +7 more
TL;DR: A 320-channel active probe for high-spatial-resolution neuromonitoring and responsive neurostimulation has been experimentally validated in epileptic seizure propagation studies in a mouse hippocampal slice in vitro and in responsive neuro stimulation for seizure suppression in an acute epilepsy rat model in vivo.