A molecular switch in sulfur metabolism to reduce arsenic and enrich selenium in rice grain.
Sheng-Kai Sun,Xuejie Xu,Zhong Tang,Zhu Tang,Xin-Yuan Huang,Markus Wirtz,Rüdiger Hell,Fang-Jie Zhao +7 more
TLDR
In this paper, the authors report the identification of the gain-of-function arsenite tolerant 1 (astol1) mutant of rice that benefits from enhanced sulfur and selenium assimilation, arsenic tolerance, and decreased arsenic accumulation in grains.Abstract:
Rice grains typically contain high levels of toxic arsenic but low levels of the essential micronutrient selenium. Anthropogenic arsenic contamination of paddy soils exacerbates arsenic toxicity in rice crops resulting in substantial yield losses. Here, we report the identification of the gain-of-function arsenite tolerant 1 (astol1) mutant of rice that benefits from enhanced sulfur and selenium assimilation, arsenic tolerance, and decreased arsenic accumulation in grains. The astol1 mutation promotes the physical interaction of the chloroplast-localized O-acetylserine (thiol) lyase protein with its interaction partner serine-acetyltransferase in the cysteine synthase complex. Activation of the serine-acetyltransferase in this complex promotes the uptake of sulfate and selenium and enhances the production of cysteine, glutathione, and phytochelatins, resulting in increased tolerance and decreased translocation of arsenic to grains. Our findings uncover the pivotal sensing-function of the cysteine synthase complex in plastids for optimizing stress resilience and grain quality by regulating a fundamental macronutrient assimilation pathway.read more
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Toxic metals and metalloids: Uptake, transport, detoxification, phytoremediation, and crop improvement for safer food
TL;DR: In this article, a number of genes involved in toxic metal uptake, transport, and detoxification have been identified, offering targets for genetic manipulation via gene editing or transgenic technologies.
Journal ArticleDOI
Toxic metals and metalloids: Uptake, transport, detoxification, phytoremediation, and crop improvement for safer food
TL;DR: In this article , a number of genes involved in toxic metal uptake, transport, and detoxification have been identified, offering targets for genetic manipulation via gene editing or transgenic technologies.
Journal ArticleDOI
Arsenic transport and interaction with plant metabolism: Clues for improving agricultural productivity and food safety.
Jie Zhang,Ameer Hamza,Zuoming Xie,Sajad Hussain,Marian Brestic,Mukarram Ali Tahir,Zaid Ulhassan,Min Yu,Suleyman I. Allakhverdiev,Sergey Shabala,Sergey Shabala +10 more
TL;DR: In this article, the molecular basis of arsenic uptake and transport in plants and the prospects of creating low As-accumulating crop species, for both agricultural productivity and food safety, are discussed.
Journal ArticleDOI
Application of CRISPR/Cas9 in Crop Quality Improvement
Qier Liu,Fan Yang,Jingjuan Zhang,Hang Liu,Shanjida Rahman,Shahidul Islam,Wujun Ma,Maoyun She +7 more
TL;DR: In this article, a review summarizes the current application of CRISPR/Cas9 technology in crop quality improvement, including modulation in appearance, palatability, nutritional components and other preferred traits of various crops.
Journal ArticleDOI
Antioxidants as modulators of arsenic-induced oxidative stress tolerance in plants: An overview
TL;DR: In this article , the authors consider how different types of antioxidants participate in the oxidative defense mechanism to alleviate As stress in plants and discuss various strategies to improve As-induced oxidative tolerance in plants such as exogenous supplementation of effective growth regulators, protectant chemicals, transgenic approaches, and genome editing.
References
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TL;DR: Burrows-Wheeler Alignment tool (BWA) is implemented, a new read alignment package that is based on backward search with Burrows–Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps.
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Journal ArticleDOI
Transporters of arsenite in rice and their role in arsenic accumulation in rice grain
Jian Feng Ma,Naoki Yamaji,Namiki Mitani,Xiao-Yan Xu,Yu-Hong Su,Steve P. McGrath,Fang-Jie Zhao +6 more
TL;DR: It is reported that two different types of transporters mediate transport of arsenite, the predominant form of arsenic in paddy soil, from the external medium to the xylem, which explains why rice is efficient in arsenic accumulation.