A Novel Coronavirus Genome Identified in a Cluster of Pneumonia Cases - Wuhan, China 2019-2020
Wenjie Tan,Xiang Zhao,Xuejun Ma,Wenling Wang,Peihua Niu,Wenbo Xu,George F. Gao,Guizhen Wu,Guizhen Wu +8 more
- Vol. 2, Iss: 4, pp 61-62
Citations
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Pentagalloylglucose, a phytochemical from Terminalia chebula can efficiently prevent SARS-CoV-2 entry: In Silico study
TL;DR: Pentagalloylglucose present in Terminalia chebula can be a better phytochemical against spike protein S1 similar to hemagglutinin of influenza virus and can be further used as a drug against SARS-CoV-2.
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COVID-19 Infection in a Child With Thalassemia Major After Hematopoietic Stem Cell Transplant
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SARS-CoV-2 Receptor and Renin-Angiotensin System Regulation: Impact of Genetics Variants in ACE2 Gene Impact of Genetics Variants in the ACE2 Gene in the Functional Receptor of SARS-CoV-2
TL;DR: The evolutionary time of contact of the human ACE2 to the virus is short and, therefore, it did not suffer sufficient selective pressures to offer resistance to viral spike protein binding at the population level.
Journal ArticleDOI
Proteome organization of COVID-19: Illustrating targets for vaccine development
TL;DR: Proteome analysis has revealed the critical mutated proteins that are responsible for COVID-19 pathogenesis and virulence and could be used to develop a predictable model for such pathogenic infections, preparing ourselves to take preventive action against its reoccurrence.
Journal ArticleDOI
The treatment of children infected with COVID-19 in a non-core hospital
Dmitry O. Ivanov,Dmitry V. Zabolotskii,Victor A. Koriachkin,Yury S. Alexandrovich,Vladimir V. Kopylov,Viktor G. Puzyrev,Anna S. Nabieva,Valeria V. Bondarenko,Svetlana L. Bannova,Anastasia S. Ustinova,Viktor V. Pogorelchuk +10 more
TL;DR: In this article, the authors present modern ideas about the amount of laboratory tests in cases of suspected presence of the SARS-CoV-2 virus, methods of radio diagnostic (computer tomography, x-ray, thorax ultrasound), features of the clinical course of infection in children depending on the severity of the of infection and indicated detailed criteria for severe forms of coronavirus infection.
References
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MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
Kazutaka Katoh,Daron M. Standley +1 more
TL;DR: This version of MAFFT has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update.
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A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.
Stéphane Guindon,Olivier Gascuel +1 more
TL;DR: This work has used extensive and realistic computer simulations to show that the topological accuracy of this new method is at least as high as that of the existing maximum-likelihood programs and much higher than the performance of distance-based and parsimony approaches.
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From “A”IV to “Z”IKV: Attacks from Emerging and Re-emerging Pathogens
George F. Gao,George F. Gao +1 more
TL;DR: 100 years after the infamous “Spanish flu” pandemic, the 2017–2018 flu season has been severe, with numerous infections worldwide.
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