A Novel Coronavirus Genome Identified in a Cluster of Pneumonia Cases - Wuhan, China 2019-2020
Wenjie Tan,Xiang Zhao,Xuejun Ma,Wenling Wang,Peihua Niu,Wenbo Xu,George F. Gao,Guizhen Wu,Guizhen Wu +8 more
- Vol. 2, Iss: 4, pp 61-62
Citations
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Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial.
Shengli Xia,Yuntao Zhang,Y. Wang,Hui Wang,Yunkai Yang,George F. Gao,Wenjie Tan,Guizhen Wu,Miao Xu,Zhiyong Lou,Weijin Huang,Wenbo Xu,Baoying Huang,Huijuan Wang,Wei Wang,Wei Zhang,Na Li,Zhiqiang Xie,Ling Ding,Wangyang You,Yuxiu Zhao,Xuqin Yang,Yang Liu,Qian Wang,Lili Huang,Yongli Yang,Guangxue Xu,Bojian Luo,Wenling Wang,Peipei Liu,Wanshen Guo,Xiaoming Yang +31 more
TL;DR: The primary outcomes were safety and tolerability and immunogenicity, assessed as the neutralising antibody responses against infectious SARS-CoV-2, and no serious adverse event was reported within 28 days post vaccination.
Posted ContentDOI
Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictions
TL;DR: Using a transmission model, a basic reproductive number is estimated for Wuhan coronavirus (2019-nCoV) and it is estimated that 58-76% of transmissions must be prevented to stop increasing.
Journal ArticleDOI
Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China.
Yueying Pan,Hanxiong Guan,Shuchang Zhou,Yujin Wang,Qian Li,Tingting Zhu,Qiongjie Hu,Liming Xia +7 more
TL;DR: The manifestations of the novel coronavirus pneumonia are diverse and change rapidly, and Radiologists should be aware of the various features of the disease and temporal changes and strengthen the recognition of image changes to help clinicians to diagnose quickly and accurately.
Journal ArticleDOI
The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China.
Yongshi Yang,Fujun Peng,Runsheng Wang,Kai Guan,Taijiao Jiang,Guogang Xu,Jinlyu Sun,Christopher Chang,Christopher Chang +8 more
TL;DR: It is clear that finding an effective antiviral and developing a vaccine are still significant challenges, as the SARS-CoV-2 virus has led to significant sociological, psychological and economic effects globally.
Journal ArticleDOI
Artificial intelligence-enabled rapid diagnosis of patients with COVID-19.
Xueyan Mei,Hao-Chih Lee,Kaiyue Diao,Mingqian Huang,Bin Lin,Chenyu Liu,Zongyu Xie,Yixuan Ma,Philip M. Robson,Michael H. Chung,Adam Bernheim,Venkatesh Mani,Claudia Calcagno,Kunwei Li,Shaolin Li,Hong Shan,Jian Lv,Tongtong Zhao,Junli Xia,Qihua Long,Sharon Steinberger,Adam Jacobi,Timothy W. Deyer,Marta Luksza,Fang Liu,Brent P. Little,Zahi A. Fayad,Yang Yang +27 more
TL;DR: Artificial intelligence algorithms integrating chest CT findings with clinical symptoms, exposure history and laboratory testing to rapidly diagnose patients who are positive for COVID-19 with similar accuracy as compared to a senior radiologist.
References
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MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
Kazutaka Katoh,Daron M. Standley +1 more
TL;DR: This version of MAFFT has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update.
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A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.
Stéphane Guindon,Olivier Gascuel +1 more
TL;DR: This work has used extensive and realistic computer simulations to show that the topological accuracy of this new method is at least as high as that of the existing maximum-likelihood programs and much higher than the performance of distance-based and parsimony approaches.
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From “A”IV to “Z”IKV: Attacks from Emerging and Re-emerging Pathogens
George F. Gao,George F. Gao +1 more
TL;DR: 100 years after the infamous “Spanish flu” pandemic, the 2017–2018 flu season has been severe, with numerous infections worldwide.
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