A Novel Coronavirus Genome Identified in a Cluster of Pneumonia Cases - Wuhan, China 2019-2020
Wenjie Tan,Xiang Zhao,Xuejun Ma,Wenling Wang,Peihua Niu,Wenbo Xu,George F. Gao,Guizhen Wu,Guizhen Wu +8 more
- Vol. 2, Iss: 4, pp 61-62
Citations
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Laboratory Findings from 100 Patients with COVID-19 Pneumonia in Madinah, Saudi Arabia
TL;DR: Combining assessment of clinical and laboratory findings could facilitate early diagnosis of COVID-19 pneumonia and the potential risk factors of older age, lymphopenia, d-dimer greater than 1μg/mL and ferritin greater than 500ng/mL could help physicians to identify patients with a poor prognosis at an early stage.
Journal ArticleDOI
Repeated Nucleic Acid Tests Are Necessary for Early Diagnosis of Atypical COVID-19: A Case Report
TL;DR: In Wuhan, China, the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported on December 8, 2019 and the patient’s symptoms included fever, coughing and breathing diffi...
Posted Content
Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through analysis of Viral Genomics and Structure
Halie M. Rando,Adam L. MacLean,Alexandra J. Lee,Sandipan Ray,Vikas Bansal,Ashwin N Skelly,Elizabeth Sell,John J. Dziak,Lamonica Shinholster,Lucy D'Agostino McGowan,Marouen Ben Guebila,Nils Wellhausen,Sergey Knyazev,Simina M. Boca,Stephen Capone,Yanjun Qi,YoSon Park,Yuchen Sun,David Mai,Christian Brueffer,James Brian Byrd,Jinhui Wang,Ronan Lordan,Ryan Velazquez,Gregory L. Szeto,John P. Barton,Rishi R. Goel,Serghei Mangul,Tiago Lubiana,Anthony Gitter,Casey S. Greene +30 more
TL;DR: In this article, the authors contextualize SARS-CoV-2 among other coronaviruses and identify what is known and what can be inferred about its behavior once inside a human host.
Journal ArticleDOI
A comprehensive update on the structure and synthesis of potential drug targets for combating the coronavirus pandemic caused by SARS‐CoV‐2
TL;DR: A brief discussion on the activity and synthesis of some active molecules such as favipiravir, hydroxychloroquine, pirfenidone, remdesivir, lopinavir, camostat, chloroquines, baricitinib, molnupiravIR, and so forth, which are under trial are presented.
Respiratory care in Covid-19/ Cuidado respiratorio en COVID-19
Carmen Chica-Meza,Luis Alexander Peña-López,Héctor Fabio Villamarín-Guerrero,Jorge Enrique Moreno-Collazos,Lizeth Catherine Rodríguez-Corredor,Wilson M. Lozano,Mónica Patricia Vargas-Ordoñez +6 more
TL;DR: No specific treatment for the new disease has been defined, with symptomatic control as the main therapeutic measure, and the use of biosecurity equipment in order to prevent transmission is recommended.
References
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MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
Kazutaka Katoh,Daron M. Standley +1 more
TL;DR: This version of MAFFT has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update.
Journal ArticleDOI
A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.
Stéphane Guindon,Olivier Gascuel +1 more
TL;DR: This work has used extensive and realistic computer simulations to show that the topological accuracy of this new method is at least as high as that of the existing maximum-likelihood programs and much higher than the performance of distance-based and parsimony approaches.
Journal ArticleDOI
From “A”IV to “Z”IKV: Attacks from Emerging and Re-emerging Pathogens
George F. Gao,George F. Gao +1 more
TL;DR: 100 years after the infamous “Spanish flu” pandemic, the 2017–2018 flu season has been severe, with numerous infections worldwide.
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