A Novel Coronavirus Genome Identified in a Cluster of Pneumonia Cases - Wuhan, China 2019-2020
Wenjie Tan,Xiang Zhao,Xuejun Ma,Wenling Wang,Peihua Niu,Wenbo Xu,George F. Gao,Guizhen Wu,Guizhen Wu +8 more
- Vol. 2, Iss: 4, pp 61-62
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Evolution of Anti-SARS-CoV-2 Therapeutic Antibodies
Juan Carlos Almagro,Gabriela Mellado-Sánchez,Martha Pedraza-Escalona,Sonia Mayra Pérez-Tapia +3 more
TL;DR: One of the conclusions of the review is that the EUA therapeutic antibodies that still retain efficacy against new VOCs bind an epitope formed by conserved residues that seem to be evolutionarily conserved as thus, critical for the RBD:hACE-2 interaction.
Journal ArticleDOI
Coronavirus disease 2019 (COVID-19): chest CT characteristics benefit to early disease recognition and patient classification-a single center experience
TL;DR: Peripheral lung distributed GGO and consolidation, without subpleural sparing, are the most common manifestations on chest CT of COVID-19, which may help to early recognition and rapid diagnosis of this disease.
Journal ArticleDOI
Knowledge, Attitude and Practice Toward COVID-19 Pandemic Among Population Visiting Dessie Health Center for COVID-19 Screening, Northeast Ethiopia
TL;DR: In this article, the authors determined the magnitude of knowledge, attitude, and practice toward COVID-19 among the population who visited the health center for COVID19 screening using a simple random sampling technique and a structured questionnaire was used to obtain information related to sociodemographic characteristics.
Journal ArticleDOI
Non-invasive respiratory support for patients with novel coronavirus pneumonia: clinical efficacy and reduction in risk of infection transmission
TL;DR: The coronavirus crisis represents one of the most devastating events of the twenty-first century, and even as the disease shows few signs of abating despite pro
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Binding and structural basis of equine ACE2 to RBDs from SARS-CoV, SARS-CoV-2 and related coronaviruses
Zepeng Xu,Xinrui Kang,Pu Han,Pei Du,Lin-jie Li,Anqi Zheng,Chu-Xia Deng,Jianxun Qi,Xin Zhao,Qihui Wang,Kefang Liu,George F. Gao +11 more
TL;DR: In this paper , the binding between equine angiotensin converting enzyme 2 (eqACE2) and the receptor binding domains (RBDs) of SARS-CoV, SARS CoV-2 prototype (PT) and variant of concerns (VOCs), as well as their close relatives bat-origin coronavirus (CoV) RaTG13 and pangolin-origin CoVs GX/P2V/2017 and GD/1/2019, were tested.
References
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MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
Kazutaka Katoh,Daron M. Standley +1 more
TL;DR: This version of MAFFT has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update.
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A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.
Stéphane Guindon,Olivier Gascuel +1 more
TL;DR: This work has used extensive and realistic computer simulations to show that the topological accuracy of this new method is at least as high as that of the existing maximum-likelihood programs and much higher than the performance of distance-based and parsimony approaches.
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From “A”IV to “Z”IKV: Attacks from Emerging and Re-emerging Pathogens
George F. Gao,George F. Gao +1 more
TL;DR: 100 years after the infamous “Spanish flu” pandemic, the 2017–2018 flu season has been severe, with numerous infections worldwide.
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