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A Novel Coronavirus Genome Identified in a Cluster of Pneumonia Cases - Wuhan, China 2019-2020

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The article was published on 2020-01-01 and is currently open access. It has received 558 citations till now. The article focuses on the topics: Coronavirus.

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Epidemiology of COVID-19 Among Children in China.

TL;DR: The distribution of children’s COVID-19 cases varied with time and space, and most of the cases were concentrated in Hubei province and surrounding areas, providing strong evidence of human-to-human transmission.
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Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China.

TL;DR: This work aims to investigate the clinical characteristic and allergy status of patients infected with SARS‐CoV‐2 and its spread around the world.
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Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study.

TL;DR: The CT findings across different timepoints throughout the COVID-19 pneumonia course were described, with rapid evolution from focal unilateral to diffuse bilateral ground-glass opacities that progressed to or co-existed with consolidations within 1–3 weeks.
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Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2.

TL;DR: The crystal structure of the C-terminal domain of SARS-CoV-2 (SARS- coV- 2-CTD) spike (S) protein in complex with human ACE2 (hACE2) is presented, which reveals a hACE2-binding mode similar overall to that observed for SARS -CoV.
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Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection.

TL;DR: With a longer time after the onset of symptoms, CT findings were more frequent, including consolidation, bilateral and peripheral disease, greater total lung involvement, linear opacities, “crazy-paving” pattern and the “reverse halo” sign.
References
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Journal ArticleDOI

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

TL;DR: This version of MAFFT has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update.
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A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.

TL;DR: This work has used extensive and realistic computer simulations to show that the topological accuracy of this new method is at least as high as that of the existing maximum-likelihood programs and much higher than the performance of distance-based and parsimony approaches.
Journal ArticleDOI

From “A”IV to “Z”IKV: Attacks from Emerging and Re-emerging Pathogens

TL;DR: 100 years after the infamous “Spanish flu” pandemic, the 2017–2018 flu season has been severe, with numerous infections worldwide.
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