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Journal ArticleDOI

Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial (ACDC study, NCT00447304).

TLDR
In this large, randomized trial, laparoscopic cholecystectomy within 24 hours of hospital admission was shown to be superior to the conservative approach concerning morbidity and costs, and it is believed that immediate lapar surgical surgery should become therapy of choice for acute choleCystitis in operable patients.
Abstract
Objective:Acute cholecystitis is a common disease, and laparoscopic surgery is the standard of care.Background:Optimal timing of surgery for acute cholecystitis remains controversial: either early surgery shortly after hospital admission or delayed elective surgery after a conservative treatment wit

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Journal ArticleDOI

Tokyo Guidelines 2018: flowchart for the management of acute cholecystitis.

Kohji Okamoto, +58 more
TL;DR: In the Tokyo Guidelines 2018 (TG18) as discussed by the authors, the authors proposed a flowchart for the treatment of acute cholecystitis (AC) in advanced centers with specialized surgeons experienced in this procedure.
Journal ArticleDOI

EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones

TL;DR: The EASL Clinical Practice Guidelines (CPG) on the prevention, diagnosis and therapy of gallstones aim to provide current recommendations on the following issues.
Journal ArticleDOI

2016 WSES guidelines on acute calculous cholecystitis

Luca Ansaloni, +51 more
TL;DR: The algorithm is proposed: as soon as diagnosis is made and after the evaluation of choledocholitiasis risk, laparoscopic cholecystectomy should be offered to all patients exception of those with high risk of morbidity or mortality.
Journal ArticleDOI

2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis

TL;DR: Early laparoscopic cholecystectomy (ELC) should be the standard of care whenever possible, even in subgroups of patients who are considered fragile, such as the elderly; those with cardiac disease, renal disease and cirrhosis; or those who are generally at high risk for surgery.
Journal ArticleDOI

Meta-analysis comparing early versus delayed laparoscopic cholecystectomy for acute cholecystitis

TL;DR: A meta‐analysis was undertaken to compare the cost‐effectiveness, quality of life, safety and effectiveness of ELC versus DLC.
References
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Journal ArticleDOI

A nationwide study of conversion from laparoscopic to open cholecystectomy.

TL;DR: Three quarters of all cholecystectomies are performed laparoscopic, and the national conversion rate is 5% to 10%.
Journal ArticleDOI

Meta‐analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis

TL;DR: In many countries laparoscopic cholecystectomy for acute choleCystitis is mainly performed after the acute episode has settled because of the anticipated increased risk of morbidity and higher conversion rate from Laparoscopic to open chole cystectomy.
Journal ArticleDOI

Management of acute cholecystitis in the laparoscopic era: results of a prospective, randomized clinical trial.

TL;DR: Despite a high conversion rate, early laparoscopic cholecystectomy offered significant advantages in the management of acute choleCystitis compared to a conservative strategy, and the greatest advantage was a reduced total hospital stay.
Journal ArticleDOI

Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: a prospective randomized trial

TL;DR: Early laparoscopic cholecystectomy for acute choleCystitis is safe and feasible, offering the additional benefit of a shorter hospital stay, and should be offered to patients with acute choelcystitis.
Journal ArticleDOI

Early versus delayed-interval laparoscopic cholecystectomy for acute cholecystitis: a metaanalysis.

TL;DR: Evidence suggested that early laparoscopic cholecystectomy reduced the total length of hospital stay and the risk of readmissions attributable to recurrent acute choleCystitis, it is therefore a more cost-effective approach for the management of acute choelcystitis.
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