Journal ArticleDOI
Adverse effect of combination of chronic psychosocial stress and high fat diet on hippocampus-dependent memory in rats
Karem H. Alzoubi,Khalid K. Abdul-Razzak,Omar F. Khabour,G. M. Al-Tuweiq,Mohammad A. Alzubi,Karim A. Alkadhi +5 more
TLDR
DTC value for above groups indicated that chronic stress or HFD, alone, resulted in a mild impairment of spatial memory, but the combination of chronic stress and HFD resulting in a more severe and long-lasting memory impairment.About:
This article is published in Behavioural Brain Research.The article was published on 2009-12-01. It has received 85 citations till now. The article focuses on the topics: Chronic stress & Water maze.read more
Citations
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Journal ArticleDOI
A critical review of chronic stress effects on spatial learning and memory
TL;DR: How chronic stress alters hippocampal spatial ability likely depends upon the engagement of other brain structures during behavioral training and testing.
Journal ArticleDOI
Neurobiological basis of chemotherapy-induced cognitive impairment: a review of rodent research.
TL;DR: The role of the blood-brain barrier, neurogenesis, oxidative stress, white matter, immune system/(neuro) inflammation, HPA axis, blood flow, and cancer in chemotherapy-induced cognitive impairment is reviewed.
Journal ArticleDOI
Effects of high-fat diet exposure on learning & memory.
TL;DR: The techniques most often used to assess learning and memory in rodent models are reviewed and findings from studies assessing the cognitive effects of high-fat diet consumption are discussed, consider potential underlying mechanisms in the brain, and conclude by reviewing emerging literature suggesting that maternal consumption of a high-Fat diet may have effects on the learning andMemory of offspring.
Journal ArticleDOI
Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats
Hiranya Pintana,Nattayaporn Apaijai,Wasana Pratchayasakul,Nipon Chattipakorn,Siriporn C. Chattipakorn +4 more
TL;DR: It is found that in the HFD group, metformin significantly attenuated the insulin resistant condition by improving metabolic parameters, decreasing peripheral and brain oxidative stress levels, and improving learning behavior, compared to the vehicle-treated group.
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The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment: the role of oxidative stress.
TL;DR: It is revealed that chronic sleep deprivation impaired both (short- and long-term) memories (P<0.05), while vitamin E treatment prevented such effect, probably through its antioxidant action in the hippocampus.
References
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Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
TL;DR: As an adjunct to pharmaceutical therapy, social and behavioral interventions such as regular physical activity and social support reduce the chronic stress burden and benefit brain and body health and resilience.
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Stress and glucocorticoids impair retrieval of long-term spatial memory
TL;DR: It is shown that rats have impaired performance in a water-maze spatial task after being given footshock 30 min before retention testing but are not impaired when footshock is given 2’min or 4 h before testing, which suggests that the retention impairment is directly related to increased adrenocortical function.
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Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
Boldizsár Czéh,Thomas Michaelis,Takashi Watanabe,Jens Frahm,G. de Biurrun,M. van Kampen,Alessandro Bartolomucci,Eberhard Fuchs +7 more
TL;DR: The effect of tianeptine, a modified tricyclic antidepressant, in the chronic psychosocial stress model of adult male tree shrews, a model with high validity for research on the pathophysiology of major depression, is investigated.
Journal ArticleDOI
Cardiovascular risk factors and cognitive decline in middle-aged adults
D. S. Knopman,Lori L. Boland,Thomas H. Mosley,George Howard,Duanping Liao,Moyses Szklo,Paul G. McGovern,Aaron R. Folsom +7 more
TL;DR: Hypertension and diabetes mellitus were positively associated with cognitive decline over 6 years in this late middle-aged population and interventions aimed at hypertension or diabetes that begin before age 60 might lessen the burden of cognitive impairment in later life.
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Dietary fat intake and the risk of incident dementia in the Rotterdam study
Sandra Kalmijn,Lenore J. Launer,Alewijn Ott,Jacqueline C.M. Witteman,Albert Hofman,Monique M.B. Breteler +5 more
TL;DR: It is suggested that a high saturated fat and cholesterol intake increases the risk of dementia, whereas fish consumption may decrease this risk.