An Enumerated Outlook of Intracellular Micropolarity Using Solvatochromic Organic Fluorescent Probes.
Kaushik Pal,Tanoy Dutta,Apurba L. Koner +2 more
- Vol. 6, Iss: 1, pp 28-37
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The spatiotemporal distribution of intracellular physical parameters of a live cell is heterogeneous and complex as mentioned in this paper, and measuring physical properties inside given cellular compartments (organelles) is ch...Abstract:
The spatiotemporal distribution of intracellular physical parameters of a live cell is heterogeneous and complex. Measuring physical properties inside given cellular compartments (organelles) is ch...read more
Citations
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ICT based water-soluble fluorescent probe for discriminating mono and dicarbonyl species and analysis in foods.
TL;DR: In this paper, a unique and highly water-soluble ICT-based fluorescent probe is developed for efficient detection and discrimination of reactive monocarbonyl formaldehyde (FA) from dicarbonyls methyl glyoxal (MGO)/glyoxal(GO) by modulating the ICT process, which was confirmed by photophysical and TD-DFT analysis.
Journal ArticleDOI
Emerging solvatochromic push-pull dyes for monitoring the lipid order of biomembranes in live cells.
Yosuke Niko,Andrey S. Klymchenko +1 more
TL;DR: In this paper, an overview of the works recently developed solvatochromic dyes have enabled, with a particular focus on those based on pyrene and Nile red.
Journal ArticleDOI
An efficient PeT based fluorescent probe for mapping mitochondrial oxidative stress produced via the Nox2 pathway.
TL;DR: A unique pentacyclic pyridinium probe, PM-S, was developed that exhibited efficient photoinduced electron transfer (PeT) with HOCl triggered methyl(phenyl)sulfane and can offer an advanced platform for monitoring the inflammatory process more efficiently.
Journal ArticleDOI
A Fluorogenic Far Red-Emitting Molecular Viscometer for Ascertaining Lysosomal Stress in Live Cells and Caenorhabditis elegans
TL;DR: A new class of Julolidine-based molecular viscometers with an extended π-conjugation with the potential to monitor lysosomal health in pathogenic conditions is developed and JIND-Mor is specifically designed to target lyssomes via simple modification.
Journal ArticleDOI
Synthesis and photophysical properties of a new push-pull pyrene dye with green-to-far-red emission and its application to human cellular and skin tissue imaging.
Kazuki Inoue,S. Kawakami,Masato Murakami,Taku Nakayama,Shinkuro Yamamoto,Keiji Inoue,Teruko Tsuda,Koji Sayama,Takeshi Imamura,Daisuke Kaneno,Shingo Hadano,Shigeru Watanabe,Yosuke Niko +12 more
TL;DR: The results suggest that PC could replace several commonly used dyes in various biological applications, particularly the rapid and accurate diagnosis of tissue diseases, typified by biopsy.
References
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Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications
Jacek Zielonka,Joy Joseph,Adam Sikora,Micael Hardy,Olivier Ouari,Jeannette Vasquez-Vivar,Gang Cheng,Marcos Lopez,Balaraman Kalyanaraman +8 more
TL;DR: The physicochemical basis for mitochondrial accumulation of lipophilic cations, synthetic chemistry strategies to target compounds to mitochondria, mitochondrial probes, and sensors, and examples of mitochondrial targeting of bioactive compounds are described.
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Macro-/micro-environment-sensitive chemosensing and biological imaging
Zhigang Yang,Zhigang Yang,Jianfang Cao,Yanxia He,Yanxia He,Jung Ho Yang,Taeyoung Kim,Xiaojun Peng,Jong Seung Kim +8 more
TL;DR: A number of various environment-responsive chemosensors related to fluorescent recognition of viscosity, polarity, temperature, hypoxia, and pH that have been reported thus far are reviewed.
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Fluorescent probes for organelle-targeted bioactive species imaging
TL;DR: The design, applications, challenges and potential directions of organelle-targeted bioactive species probes are described.
Journal ArticleDOI
Monitoring biophysical properties of lipid membranes by environment-sensitive fluorescent probes.
TL;DR: These probes are efficient for studying the microscopic analogs of viscosity, polarity, and hydration, as well as the molecular order, environment relaxation, and electrostatic potentials at the sites of their location.
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Ratiometric Fluorescence Imaging of Cellular Polarity: Decrease in Mitochondrial Polarity in Cancer Cells
TL;DR: The mitochondrial polarity in cancer cells was found to be lower than that of normal cells by ratiometric fluorescence imaging with BOB, a fluorescent probe that possesses high specificity to mitochondria that is independent of the mitochondrial membrane potential.
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