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An update on epidemiology of anaphylaxis in children and adults

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TLDR
Emerging evidence suggests that low vitamin D levels may be associated with risk of anaphylaxis and food allergy; however, further studies are required to confirm this.
Abstract
Purpose of reviewThe purpose of the present review is to describe the epidemiology of food-induced, medication-induced, drug-induced, and insect sting-induced anaphylaxis; to summarize recent changes in the incidence of anaphylaxis internationally; and to discuss recent insights into potential risk

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Citations
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Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.

TL;DR: It is shown that high-fiber feeding in mice improved oral tolerance and protected against food allergy by enhancing retinal dehydrogenase activity in CD103(+) DC, and depended on vitamin A in the diet.
Journal ArticleDOI

About the role and underlying mechanisms of cofactors in anaphylaxis

TL;DR: A better understanding of the underlying mechanisms of anaphylaxis is warranted to improve patient management modalities and a review aims to update clinicians and clinical scientists on recent developments.
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Early treatment of food-induced anaphylaxis with epinephrine is associated with a lower risk of hospitalization.

TL;DR: In this population of patients with food-induced anaphylaxis, early treatment of FIA with epinephrine was associated with significantly lower risk of hospitalization, and this study supports the benefit of prompt administration ofEpinephrine for the Treatment of FIA.
Journal ArticleDOI

Undernotification of anaphylaxis deaths in Brazil due to difficult coding under the ICD-10.

TL;DR: Brazilian mortality data were used as a case study to call attention to the inadequacy of the ICD‐10 for the measurement of anaphylaxis deaths.
References
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Journal ArticleDOI

Fatalities due to anaphylactic reactions to foods.

TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Food Allergy Among Children in the United States

TL;DR: Several national health surveys indicate that food allergy prevalence and/or awareness has increased among US children in recent years.
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Time trends in allergic disorders in the UK

TL;DR: The prevalence and healthcare usage for eczema and hay fever have increased substantially over recent decades, but may now be stabilising or even falling, while admissions for some systemic allergic diseases have risen sharply in the last decade which may indicate a rising incidence of these conditions.
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Anaphylaxis fatalities and admissions in Australia

TL;DR: The demographics for anaphylaxis deaths are different to those for anphylaxis presentations, with the exception of drug-induced anaphlyaxis deaths, which have increased.
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