An Updated Review of Tyrosinase Inhibitors
Reads0
Chats0
TLDR
This article surveys tyrosinase inhibitors newly discovered from natural and synthetic sources and the inhibitory strength is compared with that of a standard inhibitor, kojic acid, and their inhibitory mechanisms are discussed.Abstract:
Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic browning reactions in damaged fruits during post-harvest handling and processing. Neither hyperpigmentation in human skin nor enzymatic browning in fruits are desirable. These phenomena have encouraged researchers to seek new potent tyrosinase inhibitors for use in foods and cosmetics. This article surveys tyrosinase inhibitors newly discovered from natural and synthetic sources. The inhibitory strength is compared with that of a standard inhibitor, kojic acid, and their inhibitory mechanisms are discussed.read more
Citations
More filters
Journal ArticleDOI
Molecular docking and biological evaluation of hydroxy-substituted ( Z )-3-benzylideneindolin-2-one chalcones for the lead identification as tyrosinase inhibitors
TL;DR: The present study suggested that the strategy of predicting tyrosinase inhibition based on hydroxy-substituted (Z)-3-benzylideneindolin-2-one chalcones and their orientation would be useful for developing novel potent tyosinase inhibitors.
Journal ArticleDOI
Usefulness of Urea as a Means of Improving the Solubility of Poorly Water-Soluble Ascorbyl Palmitate.
TL;DR: The solubility test and the DPPH radical scavenging test and mushroom tyrosinase inhibition assay revealed that the activity of ASCP/UR complexes was not impaired by complex formation.
Journal ArticleDOI
Comparison of Antioxidant and Anti-Tyrosinase Activities of Pineapple (Ananas comosus) Core Extract and Luteolin Compound
Dela Vrianty,Rismawati Laila Qodariah,Wahyu Widowati,Ade Putra Fratama Sinaga,Dewi Fibrina,Edy Fachrial,I Nyoman Ehrich Lister +6 more
TL;DR: In this article, the content of phytochemical compounds, antioxidant activity, and inhibitory activity of tyrosinase enzymes by pineapple core extract (PCE), and then compared with the luteolin (LT) compound test results using Fansworth method, DPPH scavenging activity assay and tyrosinsase enzyme inhibition assay.
Journal ArticleDOI
Antioxidant, antibacterial and tyrosinase inhibiting activities of extracts from Myristica fragrans Houtt
Journal ArticleDOI
Krim ekstrak kulit delima merah (Punica granatum) menghambat peningkatan jumlah melanin sama efektifnya dengan krim hidrokuinon pada kulit marmut (Cavia porcellus) betina yang dipapar sinar UVB
TL;DR: In this paper, the 8% red pomegranate peel extract (Punica granatum) cream could prevent the increase of skin melanin in female guinea pigs (Cavia porcellus) exposed to UVB.
References
More filters
Journal ArticleDOI
Advances in flavonoid research since 1992.
TL;DR: Some of the recent advances in flavonoid research are reviewed and the role of anthocyanins and flavones in providing stable blue flower colours in the angiosperms is outlined.
Journal ArticleDOI
Tyrosinase: a comprehensive review of its mechanism.
Álvaro Sánchez-Ferrer,José Neptuno Rodríguez-López,Francisco García-Cánovas,Francisco García-Carmona +3 more
Journal ArticleDOI
Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future.
Y.-J. Kim,Hiroshi Uyama +1 more
TL;DR: This article overviews the various inhibitors obtained from natural and synthetic sources with their industrial importance, and examines the role of tyrosinase in melanin biosynthesis and its role in dermatological disorders.
Journal ArticleDOI
Chemical and Instrumental Approaches to Treat Hyperpigmentation
TL;DR: This review describes the different approaches to obtain depigmentation, suggests a classification of whitening molecules on the basis of the mechanism by which they interfere with melanogenesis, and confirms the necessity to apply standardized protocols to evaluate depigmenting treatments.
Journal ArticleDOI
Mushroom Tyrosinase: Recent Prospects
TL;DR: A study on the importance of tyrosinase, especially that derived from mushroom, and describes its biochemical character and inhibition and activation by the various chemicals obtained from natural and synthetic origins with its clinical and industrial importance in the recent prospects.
Related Papers (5)
Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future.
Y.-J. Kim,Hiroshi Uyama +1 more