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Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment.

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TLDR
The carbapenems are widely regarded as the drugs of choice for the treatment of severe infections caused by ESBL-producing Enterobacteriaceae, although comparative clinical trials are scarce and the feasible modification of guidelines for community-onset bacteremia associated with different infections are prescribed.
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This article is published in Saudi Journal of Biological Sciences.The article was published on 2015-01-01 and is currently open access. It has received 534 citations till now. The article focuses on the topics: Antibiotic resistance & Antimicrobial.

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First report of cross resistance to silver and antibiotics in Klebsiella pneumoniae isolated from patients and polluted water in Tunisia

TL;DR: Cross‐resistance between silver and beta‐lactams in clinical as well as environmental K. pneumoniae isolates from Tunisia were showed and it was shown for the first time that NDM‐1‐producing K.'s pneumoniae developed resistance to silver.
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High genetic diversity of Vibrio parahaemolyticus isolated from tidal water and mud of southern coast of South Korea.

TL;DR: A strain‐level typing tool successfully revealed the genetic diversity of multi‐serogroups and multiple antibiotic‐resistant Vibrio parahaemolyticus, differing by season, and with a high percentage of source assignments.
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Antimicrobial resistance pattern of Klebsiella spp isolated from patients in Tehran, Iran

TL;DR: Bu arastirmanin amaci Klebsiella turlerinin antimikrobiyal direncini klinik olarak belirlemektir, bu nedenle antibiyotik recete edilmeden once ilac direnci duyarlilik testi gerekli gorunmektedir.
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Phage display for the detection, analysis, disinfection, and prevention of Staphylococcus aureus

TL;DR: In this article , the authors highlight how phage display can be leveraged to design novel solutions to combat Staphylococcus aureus and provide outlooks on how this technology can be optimized for future applications.
References
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Journal ArticleDOI

Extended-spectrum beta-lactamases: a clinical update.

TL;DR: Extended-spectrum β-lactamases represent an impressive example of the ability of gram-negative bacteria to develop new antibiotic resistance mechanisms in the face of the introduction of new antimicrobial agents.
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Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance Threat

TL;DR: β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria and are now found in a significant percentage of Escherichia coli and Klebsiella pneumoniae strains in certain countries.
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A functional classification scheme for beta-lactamases and its correlation with molecular structure.

TL;DR: These enzymes are the major cause of bacterial resistance to b-lactam antibiotics and have been the subject of extensive microbiological, biochemical, and genetic investigations.
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beta-Lactamases in laboratory and clinical resistance.

TL;DR: The ability of the prevalent beta-Lactamases to cause resistance to widely used beta-lactams, whether resistance is accurately reflected in routine tests, and the extent to which the antibiogram for an organism can be used to predict the type of beta- lactamase that it produces are considered.
Related Papers (5)
Trending Questions (1)
What types of antibiotic resistance are there?

The paper discusses the production of extended-spectrum β-lactamases (ESBLs) as a significant resistance mechanism.