Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment.
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TLDR
The carbapenems are widely regarded as the drugs of choice for the treatment of severe infections caused by ESBL-producing Enterobacteriaceae, although comparative clinical trials are scarce and the feasible modification of guidelines for community-onset bacteremia associated with different infections are prescribed.About:
This article is published in Saudi Journal of Biological Sciences.The article was published on 2015-01-01 and is currently open access. It has received 534 citations till now. The article focuses on the topics: Antibiotic resistance & Antimicrobial.read more
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Dissertation
Studies on the occurrence of antibiotic-resistant bacterial strains from agriculture-associated waters and their proteomic and genomic characterizations
TL;DR: The role of the authors' natural ecosystems, especially rivers, in spreading multidrug resistant pathogenic bacteria and warrants further study and proactive interventions to prevent the pollution of water bodies is pointed out.
High Prevalence of Multidrug Resistant Pseudomonas aeruginosa Strains Recovered from Bovine Meat, Fresh and Smoked Fish in Côte d’Ivoire
Comoé Koffi Donatien Benie,N’zebo Désiré Kouame,Nadège Ahou N’gbesso-Kouadio,Sina Sylvie M. Kouame,Ahua R. Koffi,Koua T. Atobla,Solange Aka,Youan C. Tra Bi,Nathalie Guessennd,Adjéhi Dadié,Koffi Marcellin Dje,Mireille Dosso +11 more
TL;DR: High Prevalence of Multidrug Resistant Pseudomonas aeruginosa Strains Recovered from Bovine Meat, Fresh and Smoked Fish in Côte d’Ivoire Comoé Koffi Donatien 2019 is reported.
Journal ArticleDOI
Alternatives Therapeutic Approaches to Conventional Antibiotics: Advantages, Limitations and Potential Application in Medicine
Hiba Alaoui Mdarhri,Rachid Benmessaoud,Houda El Yacoubi,L. Seffar,Houda Guennouni Assimi,Mouhsine Hamam,Rihabe Boussettine,Najoie Filali-Ansari,Fatima Azzahra Lahlou,Idrissa Diawara,Moulay Mustapha Ennaji,Mohamed Kettani-Halabi +11 more
TL;DR: In this paper , a review of the emerging alternative therapies that are currently being evaluated and which may be developed in the future to break the progression of antimicrobial resistance is provided, highlighting the importance of the combination therapy approach, wherein two or more therapies are used in combination in order to more effectively combat infectious disease and increasing access to quality healthcare.
Análisis comparativo de los elementos genómicos de resistencia a antibióticos betalactámicos en cepas colombianas de Providencia rettgeri durante el período 2015 - 2016
TL;DR: Los elementos genomicos de resistencia a antibioticos betalactamicos en cepas colombianas de P. rettgeri demostraron ser un determinante importante para caracterizar los aislamientos con base en el resistoma.
References
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Journal ArticleDOI
Extended-spectrum beta-lactamases: a clinical update.
TL;DR: Extended-spectrum β-lactamases represent an impressive example of the ability of gram-negative bacteria to develop new antibiotic resistance mechanisms in the face of the introduction of new antimicrobial agents.
Journal ArticleDOI
Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study
Karthikeyan Kumarasamy,Mark Toleman,Timothy R. Walsh,Jay Bagaria,Fafhana Butt,Ravikumar Balakrishnan,Uma Chaudhary,Michel Doumith,Christian G. Giske,Seema Irfan,Padma Krishnan,Anil Kumar,Sunil Maharjan,Shazad Mushtaq,Tabassum Noorie,David L. Paterson,A. Pearson,Claire Perry,Rachel Pike,Bhargavi Rao,Ujjwayini Ray,Jayanta B. Sarma,Madhu Sharma,Elizabeth Sheridan,M A Thirunarayan,Jane F. Turton,Supriya Upadhyay,Marina Warner,William Welfare,David M. Livermore,Neil Woodford +30 more
TL;DR: The prevalence of NDM-1, in multidrug-resistant Enterobacteriaceae in India, Pakistan, and the UK is investigated, and co-ordinated international surveillance is needed.
Journal ArticleDOI
Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance Threat
TL;DR: β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria and are now found in a significant percentage of Escherichia coli and Klebsiella pneumoniae strains in certain countries.
Journal ArticleDOI
A functional classification scheme for beta-lactamases and its correlation with molecular structure.
TL;DR: These enzymes are the major cause of bacterial resistance to b-lactam antibiotics and have been the subject of extensive microbiological, biochemical, and genetic investigations.
Journal ArticleDOI
beta-Lactamases in laboratory and clinical resistance.
TL;DR: The ability of the prevalent beta-Lactamases to cause resistance to widely used beta-lactams, whether resistance is accurately reflected in routine tests, and the extent to which the antibiogram for an organism can be used to predict the type of beta- lactamase that it produces are considered.
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