Applications of nanoparticle systems in drug delivery technology
Syed A. A. Rizvi,Ayman M. Saleh +1 more
TLDR
arget and sustained drug delivery decreases the drug related toxicity and increase patient’s compliance with less frequent dosing, also providing advancement in diagnostic testing.Abstract:
The development of nanoparticle-based drug formulations has yielded the opportunities to address and treat challenging diseases. Nanoparticles vary in size but are generally ranging from 100 to 500 nm. Through the manipulation of size, surface characteristics and material used, the nanoparticles can be developed into smart systems, encasing therapeutic and imaging agents as well as bearing stealth property. Further, these systems can deliver drug to specific tissues and provide controlled release therapy. This targeted and sustained drug delivery decreases the drug related toxicity and increase patient’s compliance with less frequent dosing. Nanotechnology has proven beneficial in the treatment of cancer, AIDS and many other disease, also providing advancement in diagnostic testing.read more
Citations
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The Role of Ligands in the Chemical Synthesis and Applications of Inorganic Nanoparticles.
Amelie Heuer-Jungemann,Neus Feliu,Neus Feliu,Ioanna Bakaimi,Majd A. Hamaly,Alaaldin M. Alkilany,Alaaldin M. Alkilany,Indranath Chakraborty,Atif Masood,Maria Francesca Casula,Athanasia Kostopoulou,Eunkeu Oh,Kimihiro Susumu,Michael H. Stewart,Igor L. Medintz,Emmanuel Stratakis,Wolfgang J. Parak,Antonios G. Kanaras +17 more
TL;DR: This article analyzes the interaction of nanoparticle surface and ligands with different chemical groups, the types of bonding, the final dispersibility of ligand-coated nanoparticles in complex media, their reactivity, and their performance in biomedicine, photodetectors, photovoltaic devices, light-emitting devices, sensors, memory devices, thermoelectric applications, and catalysis.
Journal ArticleDOI
Therapeutic Nanoparticles and Their Targeted Delivery Applications.
TL;DR: Understanding of the characteristics of nanoparticles and their interactions with the biological environment will enable us to establish novel strategies for the treatment, prevention, and diagnosis in many diseases, particularly untreatable ones.
Journal ArticleDOI
Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles
TL;DR: The advantages of various drug delivery vehicles are discussed for better understanding of their utility in terms of current medical needs and the application of a wide range of nanomedicines is also described in the context of major chronic diseases.
Journal ArticleDOI
Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health.
Bahare Salehi,Laura Machín,Lianet Monzote,Javad Sharifi-Rad,Shahira M. Ezzat,Mohamed A. Salem,Rana M. Merghany,Nihal M. El Mahdy,Ceyda Sibel Kiliç,Oksana Sytar,Oksana Sytar,Mehdi Sharifi-Rad,Farukh Sharopov,Natália Martins,Miquel Martorell,William C. Cho +15 more
TL;DR: The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.
Journal ArticleDOI
Metal Oxide Nanoparticles as Biomedical Materials
Maria P. Nikolova,Murthy Chavali +1 more
TL;DR: In this review, a comprehensive review of researches on metal oxide nanoparticles, their nanoscale physicochemical properties, defining specific applications in the various fields of nanomedicine are provided.
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