Journal ArticleDOI
Bone strength at the distal radius can be estimated from high-resolution peripheral quantitative computed tomography and the finite element method.
Joshua A. MacNeil,Steven K. Boyd +1 more
TLDR
The combined numerical-experimental procedure for FE model validation on the patient micro-CT technology demonstrated that bone strength can be estimated non-invasively, and this may provide important insight into fracture risk in patient populations.About:
This article is published in Bone.The article was published on 2008-06-01. It has received 423 citations till now. The article focuses on the topics: Ultimate tensile strength & Quantitative computed tomography.read more
Citations
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Journal ArticleDOI
Reproducibility of direct quantitative measures of cortical bone microarchitecture of the distal radius and tibia by HR-pQCT ☆
TL;DR: It is indicated that HR-pQCT measures of cortical bone density and architecture can be measured in vivo with high reproducibility and limited bias across a biologically relevant range of values.
Journal ArticleDOI
Increased cortical porosity in type 2 diabetic postmenopausal women with fragility fractures
Janina M. Patsch,Andrew J. Burghardt,Samuel P. Yap,Thomas Baum,Ann V. Schwartz,Gabby B. Joseph,Thomas M. Link +6 more
TL;DR: It is suggested that severe deficits in cortical bone quality are responsible for fragility fractures in postmenopausal diabetic women.
Journal ArticleDOI
Osteoporosis Imaging: State of the Art and Advanced Imaging
TL;DR: The importance of osteoporosis is increasing in our aging society; fragility fractures may have a devastating effect on the individual, and as radiologists we have a critical role to play in preventing these as mentioned in this paper.
Journal ArticleDOI
Age-related patterns of trabecular and cortical bone loss differ between sexes and skeletal sites: a population-based HR-pQCT study.
TL;DR: The trends for less periosteal expansion, more porous cortices, and a greater percentage of load carried by the DR cortex in women may underpin sex differences in forearm fracture risk.
Journal ArticleDOI
Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia.
Andrew J. Burghardt,Galateia J. Kazakia,Sweta Ramachandran,Thomas M. Link,Sharmila Majumdar,Sharmila Majumdar +5 more
TL;DR: Age‐related differences in cortical porosity, as detected by HR‐pQCT, are more pronounced than differences in standard cortical metrics and the biomechanical significance of these structural differences increases with age for men and women and provides discriminatory information for menopause‐related bone quality effects.
References
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Journal ArticleDOI
Osteoporosis prevention, diagnosis, and therapy
Anne Klibanski,Lucile L. Adams-Campbell,Tamsen Bassford,Steven N. Blair,Scott D. Boden,Kay Dickersin,David R. Gifford,Lou Glasse,Steven R. Goldring,Keith A. Hruska,Susan R. Johnson,Laurie K. McCauley,William E. Russell +12 more
TL;DR: Though prevalent in white postmenopausal women, osteoporosis occurs in all populations and at all ages and has significant physical, psychosocial, and financial consequences.
Assessment of fracture risk and its application to screening for postmenopausal osteoporos
L. Alexeeva,P. Burkhardt,C. Christiansen,C. Cooper,P. Delmas,O. Johnell,C. Johnston,J. Kanis,P. Lips,Lee J. Melton,P. Meunier,Ego Seeman,J. Stepan,A. Tosteson,N. Khaltaev,J. P. Bonjour,H. Gong-Yi,R. Lindsay +17 more
TL;DR: There is little evidence that osteoporosis can usefully be tackled by a public health policy to influence risk factors such as smoking, exercise and nutrition, so the selective use of screening techniques will improve the cost-benefit ratio of intervention.
Assessment of fracture risk and its application to screening for postmenopausal osteoporosis
L. Alexeeva,P. Burkhardt,C. Christiansen,Cyrus Cooper,Pierre D. Delmas,Olof Johnell,C. Conrad Johnston,John A. Kanis,Paul Lips,Lee J. Melton,P. Meunier,Ego Seeman,Jan J. Stepan,A. Tosteson +13 more
Journal ArticleDOI
The elastic and ultimate properties of compact bone tissue
TL;DR: The use of a tranversely isotropic model is tested for the elastic behavior of bovine and human bone and the five independent constants of this model are determined.
Journal ArticleDOI
Perspective : how many women have osteoporosis ?
TL;DR: Osteoporosis is widely viewed as a major public health concern, but the exact magnitude of the problem is uncertain and likely to depend on how the condition is defined, and the design and implementation of control programs directed at this major health problem must be given.