Caffeine as a Factor Influencing the Functioning of the Human Body—Friend or Foe?
TLDR
In this paper, the authors present both the positive and negative sides of caffeine consumption and the healing properties of this purine alkaloid in diseases such as asthma, Parkinson's disease, and others, not forgetting about the negative effects of excess caffeine.Abstract:
Nowadays, caffeine is one of the most commonly consumed substances, which presents in many plants and products. It has both positive and negative effects on the human body, and its activity concerns a variety of systems including the central nervous system, immune system, digestive system, respiratory system, urinary tract, etc. These effects are dependent on quantity, the type of product in which caffeine is contained, and also on the individual differences among people (sex, age, diet etc.). The main aim of this review was to collect, present, and analyze the available information including the latest discoveries on the impact of caffeine on human health and the functioning of human body systems, taking into account the role of caffeine in individual disease entities. We present both the positive and negative sides of caffeine consumption and the healing properties of this purine alkaloid in diseases such as asthma, Parkinson’s disease, and others, not forgetting about the negative effects of excess caffeine (e.g., in people with hypertension, children, adolescents, and the elderly). In summary, we can conclude, however, that caffeine has a multi-directional influence on various organs of the human body, and because of its anti-oxidative properties, it was, and still is, an interesting topic for research studies including those aimed at developing new therapeutic strategies.read more
Citations
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Neurodegenerative Diseases: Can Caffeine Be a Powerful Ally to Weaken Neuroinflammation?
Melania Ruggiero,Rosa Calvello,Chiara Porro,Giovanni Messina,Antonia Cianciulli,Maria Antonietta Panaro +5 more
TL;DR: The latest research about the potential effects of caffeine in neurodegenerative disorders prevention is summarized and the role of controlled caffeine delivery systems in maintaining high plasma caffeine concentrations for an extended time is discussed.
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The medicinal and aromatic plants as ingredients in functional beverage production
Ivana Maleš,Sandra Pedisić,Zoran Zorić,I. Elez Garofulić,Maja Repajić,Lijun You,Sanda Vladimir-Knežević,Dražan Butorac,Verica Dragović-Uzelac +8 more
TL;DR: The functional beverages (FBs) market offers many opportunities for new product development with desirable and effective composition of nutrients and bioactive molecules (BAMs) aimed to deliver health benefits and improve human well-being as mentioned in this paper .
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Caffeine and Its Antioxidant Properties—It Is All about Dose and Source
Bianca Eugenia Osz,George Jîtcă,Ruxandra Ștefănescu,Amalia Pușcaș,Amelia Tero-Vescan,Camil Eugen Vari +5 more
TL;DR: In this article , a review of the effects of caffeine in modulating oxidative stress and assessing these benefits, considering the source and the dose administered, is presented, with the objective of assessing the benefits of the daily intake of caffeine from food or drink.
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Update to the Treatment of Parkinson’s Disease Based on the Gut-Brain Axis Mechanism
TL;DR: The research progress of the mechanism of the gut-brain axis (GBA) in PD is reviewed and the roles of α-synuclein, gut microbiota, immune inflammation, neuroendocrine, mitochondrial autophagy, and environmental toxins in the mechanism are discussed.
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The effect of caffeine on subsequent sleep: A systematic review and meta-analysis.
Carissa Gardiner,Jonathon Weakley,Louise M. Burke,Gregory D. Roach,Charli Sargent,Nirav Maniar,Andrew D. Townshend,Shona L. Halson +7 more
TL;DR: In this article , a systematic review and meta-analysis investigated the effect of caffeine on the characteristics of night-time sleep, with the intent to identify the time after which caffeine should not be consumed prior to bedtime.
References
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Journal ArticleDOI
Potential Role of Caffeine in the Treatment of Parkinson’s Disease
TL;DR: Emerging evidence suggests that caffeine may reduce parkinsonian motor symptoms by antagonising the adenosine A2A receptor, which is predominately expressed in the basal ganglia, and caffeine may be used as an adjuvant in treating PD.