Caffeine as a Factor Influencing the Functioning of the Human Body—Friend or Foe?
TLDR
In this paper, the authors present both the positive and negative sides of caffeine consumption and the healing properties of this purine alkaloid in diseases such as asthma, Parkinson's disease, and others, not forgetting about the negative effects of excess caffeine.Abstract:
Nowadays, caffeine is one of the most commonly consumed substances, which presents in many plants and products. It has both positive and negative effects on the human body, and its activity concerns a variety of systems including the central nervous system, immune system, digestive system, respiratory system, urinary tract, etc. These effects are dependent on quantity, the type of product in which caffeine is contained, and also on the individual differences among people (sex, age, diet etc.). The main aim of this review was to collect, present, and analyze the available information including the latest discoveries on the impact of caffeine on human health and the functioning of human body systems, taking into account the role of caffeine in individual disease entities. We present both the positive and negative sides of caffeine consumption and the healing properties of this purine alkaloid in diseases such as asthma, Parkinson’s disease, and others, not forgetting about the negative effects of excess caffeine (e.g., in people with hypertension, children, adolescents, and the elderly). In summary, we can conclude, however, that caffeine has a multi-directional influence on various organs of the human body, and because of its anti-oxidative properties, it was, and still is, an interesting topic for research studies including those aimed at developing new therapeutic strategies.read more
Citations
More filters
Journal ArticleDOI
Effects of caffeinated beverage ingestion on salivary antimicrobial proteins responses to acute exercise in the heat
Lin Cheng,Hongli Wang,Yanbai Han +2 more
TL;DR: In this paper , a double-blind, randomized crossover design was used to examine the effect of salivary α-amylase (sAA) and lactoferrin (sLac) activity in cyclists in hot environments.
Journal ArticleDOI
Beverage preference (coffee vs. tea) according to CYP1A2 gene rs2470893 SNP genotypes in the Tunisian population
TL;DR: In this paper , the association of common CYP1A2 SNPs (rs762551, rs2472297 and rs2470893) with most consumed caffeinated beverages intake (coffee and tea) was investigated.
References
More filters
Journal ArticleDOI
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
Marcy E. MacDonald,Christine Ambrose,Mabel P. Duyao,Richard H. Myers,Carol Lin,Lakshmi Srinidhi,Glenn Barnes,Sherryl A.M. Taylor,Marianne James,Nicolet Groot,Heather MacFarlane,Barbara Jenkins,Mary Anne Anderson,Nancy S. Wexler,James F. Gusella,Gillian P. Bates,Sarah Baxendale,Holger Hummerich,Susan F. Kirby,Mike North,S. Youngman,Richard Mott,Günther Zehetner,Zdenek Sedlacek,Annemarie Poustka,Anna-Maria Frischauf,Hans Lehrach,Alan Buckler,Deanna M. Church,Lynn Doucette-Stamm,Michael Conlon O'Donovan,Laura Riba-Ramirez,Manish A. Shah,Vincent P. Stanton,Scott A. Strobel,Karen M. Draths,Jennifer L. Wales,Peter B. Dervan,David E. Housman,Michael R. Altherr,Rita Shiang,Leslie M. Thompson,Thomas J. Fielder,John J. Wasmuth,Danilo A. Tagle,John Valdes,Lawrence W. Elmer,Marc W. Allard,Lucio H. Castilla,Manju Swaroop,Kris Blanchard,Francis S. Collins,Russell G. Snell,Tracey Holloway,Kathleen Gillespie,Nicole A. Datson,Duncan Shaw,Peter S. Harper +57 more
TL;DR: In this article, the authors used haplotype analysis of linkage disequilibrium to spotlight a small segment of 4p16.3 as the likely location of the defect, which is expanded and unstable on HD chromosomes.
Journal ArticleDOI
Risk Factors for Alzheimer’s Disease: A Prospective Analysis from the Canadian Study of Health and Aging
Joan Lindsay,Danielle Laurin,René Verreault,Réjean Hébert,Barbara E. Helliwell,Gerry Hill,Ian McDowell +6 more
TL;DR: Regular physical activity could be an important component of a preventive strategy against Alzheimer's disease and many other conditions, and use of nonsteroidal anti-inflammatory drugs, wine consumption, coffee consumption, and regular physical activity were associated with a reduced risk of Alzheimer's Disease.
Journal ArticleDOI
Effects of caffeine on human health.
TL;DR: It is concluded that for the healthy adult population, moderate daily caffeine intake is not associated with adverse effects such as general toxicity, cardiovascular effects, effects on bone status and calcium balance, changes in adult behaviour, increased incidence of cancer and effects on male fertility.
Journal ArticleDOI
Adenosine–dopamine receptor–receptor interactions as an integrative mechanism in the basal ganglia
Journal ArticleDOI
Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
TL;DR: The data that describe the emergence of the ancient huntingtin gene and of the polyglutamine trait during the last 800 million years of evolution are reviewed and data indicating how the loss of these beneficial activities reduces the ability of these neurons to survive are summarized.