Book ChapterDOI
Chapter 15 – docosahexaenoic acid: membrane function and metabolism
Norman Salem,Hee-Yong Kim,J. A. Yergey +2 more
- pp 263-317
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The article was published on 1986-01-01. It has received 301 citations till now. The article focuses on the topics: Docosahexaenoic acid.read more
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Journal ArticleDOI
Cardiovascular effects of n-3 fatty acids
Alexander Leaf,Peter C. Weber +1 more
TL;DR: Effets preventifs et benefiques sur l'atherosclerose et l'infarctus, dans l'alimentation, sur les lipides plasmatiques, sur le metabolisme and the fonctions des eicosanoides.
Journal ArticleDOI
Mechanisms of action of docosahexaenoic acid in the nervous system
TL;DR: Through its effects on PS, DHA may play an important role in the regulation of cell signaling and in cell proliferation, and progress has been made recently in nuclear magnetic responance studies to delineate differences in molecular structure and order in biomembranes due to subtle changes in the degree of phospholipid unsaturation.
Journal ArticleDOI
Docosahexaenoic acid: membrane properties of a unique fatty acid.
TL;DR: DHA's interaction with other membrane lipids, particularly cholesterol, may play a prominent role in modulating the local structure and function of cell membranes.
Journal ArticleDOI
Docosahexaenoic Acid, a Ligand for the Retinoid X Receptor in Mouse Brain
Alexander Mata de Urquiza,Suya Liu,Maria Sjöberg,Rolf Zetterström,William J. Griffiths,Jan Sjövall,Thomas Perlmann +6 more
TL;DR: DHA, a long-chain polyunsaturated fatty acid that is highly enriched in the adult mammalian brain, is identified as a factor in brain tissue from adult mice that activates RXR in cell-based assays, suggesting that DHA may influence neural function through activation of an RXR signaling pathway.
Journal ArticleDOI
Identification of the gene responsible for Best macular dystrophy
Konstantin Petrukhin,M. J. Koisti,B. Bakall,Wen Li,Guochun Xie,Towa Marknell,Ola Sandgren,Kristina Forsman,Gösta Holmgren,Sten Andréasson,M. Vujic,Arthur A.B. Bergen,V. Mcgarty-Dugan,David J. Figueroa,Christopher P. Austin,Michael L. Metzker,C. T. Caskey,Claes Wadelius +17 more
TL;DR: Genetic mapping data, identification of five independent disease-specific mutations and expression studies provide evidence that mutations within the candidate gene are a cause of best macular dystrophy.
References
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Journal ArticleDOI
The inverse relation between fish consumption and 20-year mortality from coronary heart disease.
TL;DR: It is concluded that the consumption of as little as one or two fish dishes per week may be of preventive value in relation to coronary heart disease.
Journal ArticleDOI
The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function
Journal ArticleDOI
Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function
Tak H. Lee,Hoover Rl,John D. Williams,Richard I. Sperling,Ravalese J rd,Bernd W. Spur,Dwight R. Robinson,E. J. Corey,Robert A. Lewis,K F Austen +9 more
TL;DR: The effects of dietary fish-oil fatty acids on the function of the 5-lipoxygenase pathway of peripheral-blood polymorphonuclear leukocytes and monocytes were determined in seven normal subjects who supplemented their usual diet with daily doses of triglycerides.
Journal ArticleDOI
Haemostatic Function and Platelet Polyunsaturated Fatty Acids in Eskimos
Jørn Dyerberg,H.O. Bang +1 more
TL;DR: Partial dietary substitution of arachidonic acid by eicosapentaenoic acid may reduce the incidence of thrombotic disorders, including myocardial infarction, among Eskimos.
Journal ArticleDOI
The composition of food consumed by Greenland Eskimos.
H O Bang,Jørn Dyerberg,N Hjøorne +2 more
TL;DR: Food specimens have been collected from Greenland Eskimo hunters and their wives, in all seven persons, on seven consecutive days, and their food was found to contain more protein and less carbohydrates than average Danish food and an almost equal amount of fat.