Journal ArticleDOI
Chitin and chitinase: Role in pathogenicity, allergenicity and health.
Seema Patel,Arun Goyal +1 more
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TLDR
This critical review discusses the complex nexus of chit in and chitinase and assesses both their pathogenic as well as utilitarian aspects.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2017-04-01. It has received 69 citations till now. The article focuses on the topics: Chitinase & Chitin.read more
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Natural products with preservative properties for enhancing the microbiological safety and extending the shelf-life of seafood: A review
TL;DR: This review focuses on thenatural preservatives studied in seafood matrices, their forms of application, concentrations usually employed, their mechanisms of action, factors that interfere in their use and the synergistic effect of the interactions among the natural preservatives, with a focus for maintenance of quality and ensure of food safety.
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Danger-Associated Molecular Patterns (DAMPs): the Derivatives and Triggers of Inflammation.
TL;DR: The limited number of recognized DAMPs are only a fraction of the vast array of other DAMPs, and efforts should be focused on the elimination of inflammatory agents.
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Cathepsins: Proteases that are vital for survival but can also be fatal.
TL;DR: By taming and harnessing cathepsins, by inhibitors and judicious lifestyle, a gamut of malignancies can be resolved and these aspects, which can be of clinical relevance, are discussed.
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Starch-binding domains as CBM families–history, occurrence, structure, function and evolution
TL;DR: The present review aims to deliver and describe the SBD identification in different amylolytic and related enzymes as well as in other relevant enzymes and proteins.
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Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles.
TL;DR: It is expected that understanding the principles and the state-of-the-art of natural nanocomposites may lead to breakthroughs in many research areas, including tissue engineering and orthopaedic devices.
References
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The carbohydrate-active enzymes database (CAZy) in 2013
TL;DR: The changes that have occurred in CAZy during the past 5 years are outlined and a novel effort to display the resolution and the carbohydrate ligands in crystallographic complexes of CAZymes is presented.
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The Universal Protein Resource (UniProt)
Amos Marc Bairoch,Rolf Apweiler,Cathy H. Wu,Winona C. Barker,Brigitte Boeckmann,Serenella Ferro,Elisabeth Gasteiger,Hongzhan Huang,Rodrigo Lopez,Michele Magrane,Maria Jesus Martin,Darren A. Natale,Claire O'Donovan,Nicole Redaschi,Lai-Su L. Yeh +14 more
TL;DR: During 2004, tens of thousands of Knowledgebase records got manually annotated or updated; the UniProt keyword list got augmented by additional keywords; the documentation of the keywords and are continuously overhauling and standardizing the annotation of post-translational modifications.
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Overview of the Immune Response
TL;DR: This overview identifies key mechanisms used by the immune system to respond to invading microbes and other exogenous threats and identifies settings in which disturbed immune function exacerbates tissue injury.
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Mucins in cancer: function, prognosis and therapy.
TL;DR: The findings that certain transmembrane mucins induce transformation and promote tumour progression have provided the experimental basis for demonstrating that inhibitors of their function are effective as anti-tumour agents in preclinical models.
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Chitin--the undisputed biomolecule of great potential
TL;DR: This most versatile amino polysaccharide, chitin, is surely an undisputed biomolecule of great potential and an unlimited R&D efforts are needed to find new applications, which are necessary to realize its full potential.