Chitosan hydrogel/3D-printed poly(ε-caprolactone) hybrid scaffold containing synovial mesenchymal stem cells for cartilage regeneration based on tetrahedral framework nucleic acid recruitment.
Pinxue Li,Liwei Fu,Zhiyao Liao,Yu Peng,Chao Ning,Cangjian Gao,Daxu Zhang,Xiang Sui,Yunfeng Lin,Shuyun Liu,Chunxiang Hao,Quanyi Guo +11 more
TLDR
In this article, a cartilage regenerative system was developed based on a chitosan (CS) hydrogel/3D-printed poly(e-caprolactone) (PCL) hybrid containing synovial MSCs and recruiting tetrahedral framework nucleic acid (TFNA) injected into the articular cavity.About:
This article is published in Biomaterials.The article was published on 2021-09-15 and is currently open access. It has received 49 citations till now. The article focuses on the topics: Chondrogenesis & Cartilage.read more
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Recent advances in 3D-printed polylactide and polycaprolactone-based biomaterials for tissue engineering applications.
Zia Ullah Arif,Muhammad Yasir Khalid,Reza Noroozi,Ali Sadeghianmaryan,Meisam Jalalvand,Mokarram Hossain +5 more
TL;DR: In this paper , the recent advancements in the PLA and PCL biodegradable polymer-based composites as well as their reinforcement with hydrogels and bio-ceramics scaffolds manufactured through 3DP are systematically summarized and the applications of bone, cardiac, neural, vascularized and skin tissue regeneration are thoroughly elucidated.
Journal ArticleDOI
Hydrogel composite scaffolds achieve recruitment and chondrogenesis in cartilage tissue engineering applications
Bo Huang,Pinxue Li,Mingxue Chen,Liqing Peng,Xujiang Luo,Guangzhao Tian,Lei Wu,Qinyu Tian,Huo Li,Yu Yang,Shuangpeng Jiang,Zhen Yang,Kangkang Zha,Xiang Sui,Shuyun Liu,Quanyi Guo +15 more
TL;DR: Wang et al. as discussed by the authors constructed a skeleton-based scaffold that can be easily molded to fill cartilage defects of any shape that fit tightly into the host cartilage, and the skeleton provided a three-dimensional microenvironment supporting cell adhesion, proliferation and chondrogenic differentiation.
Journal ArticleDOI
An immunomodulatory polypeptide hydrogel for osteochondral defect repair
Meng Yang,Zhengchu Zhang,Fu-Zhen Yuan,Rong-Hui Deng,Xin Yan,Fengbao Mao,You-Rong Chen,Hua Lu,Jia Kuo Yu +8 more
TL;DR: In this paper , a polypeptide-based PAA-RGD hydrogel was used for osteochondral repair in New Zealand white rabbits even at the early stage of implantation.
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3D Bioprinted Chitosan-Based Hydrogel Scaffolds in Tissue Engineering and Localised Drug Delivery
TL;DR: 3D bioprinting technology for the preparation of chitosan-based hydrogel scaffolds for the regeneration of tissues delivering either cells or active substances to promote restoration.
Journal ArticleDOI
Chitosan-based biomaterials for the treatment of bone disorders.
Mahdi Rahimi,Seyed Mostafa Mir,Roghayyeh Baghban,G Ginoya Charmi,Christopher M. Plummer,Vahid Shafiei-Irannejad,Jafar Soleymani,Joanna Pietrasik +7 more
TL;DR: A review of chitosan-based biomaterials for the treatment of bone disorders including bone fracture, osteoporosis, osteoarthritis, rheumatoid, and osteosarcoma can be found in this paper .
References
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Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles
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Self-Assembled Multivalent DNA Nanostructures for Noninvasive Intracellular Delivery of Immunostimulatory CpG Oligonucleotides
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Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane
Cosimo De Bari,Francesco Dell'Accio,Frank Vandenabeele,Joris Vermeesch,Jean-Marc Raymackers,Frank P. Luyten +5 more
TL;DR: Adult human synovial membrane-derived mesenchymal stem cells (hSM-MSCs) have myogenic differentiation in a nude mouse model of skeletal muscle regeneration and proof of principle of their potential use for muscle repair in the mdx mice model of Duchenne muscular dystrophy is provided.
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Chitosan oligosaccharide: Biological activities and potential therapeutic applications
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