Journal ArticleDOI
Construction of All-Carbon Quaternary Stereocenters by Scandium-Catalyzed Intramolecular C-H Alkylation of Imidazoles with 1,1-Disubstituted Alkenes.
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TLDR
The exo-selective C-H cycloaddition of imidazoles to 1,1-disubstituted alkenes has been achieved for the first time by using half-sandwich scandium catalysts and has also been achieved with a high level of enantioselectivity.Abstract:
The exo-selective C–H cycloaddition of imidazoles to 1,1-disubstituted alkenes has been achieved for the first time by using half-sandwich scandium catalysts. A wide range of imidazole compounds be...read more
Citations
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Journal ArticleDOI
Transition Metal Catalyzed Enantioselective C(sp2)–H Bond Functionalization
TL;DR: This work has shown direct catalytic transformation of C–H bonds to new functionalities has provided a powerful strategy to synthesize complex molecular scaffolds in a straightforward way.
Journal ArticleDOI
Chiral Cyclopentadienyl Ligands: Design, Syntheses, and Applications in Asymmetric Catalysis
TL;DR: A historical overview on the development of chiral derivatives of the ubiquitous cyclopentadienyl ligand (Cp X), and details their successful application in a broad range of metal-catalyzed transformations, giving access to an extensive catalogue of valuable chiral molecules.
Journal ArticleDOI
Oxygen-Linked Cyclopentadienyl Rhodium(III) Complexes-Catalyzed Asymmetric C-H Arylation of Benzo[h]quinolines with 1-Diazonaphthoquinones.
TL;DR: In this article, a tunable chiral cyclopentadienyl rhodium (CpRh) complex-catalyzed asymmetric C-H functionalization reactions have witnessed a significant progress in organic synthesis.
Journal ArticleDOI
Enantioselective C-H Alkenylation of Ferrocenes with Alkynes by Half-Sandwich Scandium Catalyst.
TL;DR: In this article, the enantioselective C-H alkenylation of quinoline and pyridine-substituted ferrocenes with alkynes by a half-sandwich scandium catalyst has been investigated.
Journal ArticleDOI
Co-syndiospecific Alternating Copolymerization of Functionalized Propylenes and Styrene by Rare-Earth Catalysts
TL;DR: This reaction efficiently afforded the corresponding functionalized propylene- alt -styrene copolymers with a perfect alternating sequence and excellent co-syndiotacticity, thus constituting the first example of co-stereospecific alternating copolymerization of polar and non-polar olefins.
References
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Journal ArticleDOI
Rhodium-Catalyzed C-C Bond Formation via Heteroatom-Directed C-H Bond Activation
TL;DR: This review focuses on Rh-catalyzed methods for C-H bond functionalization, which have seen widespread success over the course of the last decade and are discussed in detail in the accompanying articles in this special issue of Chemical Reviews.
Journal ArticleDOI
3d Transition Metals for C-H Activation.
Parthasarathy Gandeepan,Thomas Müller,Daniel Zell,Gianpiero Cera,Svenja Warratz,Lutz Ackermann +5 more
TL;DR: A comprehensive overview on first row transition metal catalysts for C-H activation until summer 2018 is provided.
Journal ArticleDOI
Palladium-Catalyzed Transformations of Alkyl C-H Bonds.
TL;DR: A number of mono- and bidentate ligands have also proven to be effective for accelerating C(sp3)-H activation directed by weakly coordinating auxiliaries, which provides great opportunities to control reactivity and selectivity in Pd-catalyzed C-H functionalization reactions.
Journal ArticleDOI
The catalytic enantioselective construction of molecules with quaternary carbon stereocenters
E. J. Corey,Angel Guzman-Perez +1 more
TL;DR: A long-standing challenge to synthesis can now be met through the use of new and powerful catalytic asymmetric reactions for the assembly of complex chiral molecules with quaternary stereocenters from achiral building blocks.
Journal ArticleDOI
Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C−H Bond Activation
TL;DR: The relevant mechanistic insights that enabled synthetic advances and distinguished the resulting transformations from other methods are emphasized and researchers will better understand the details of the aforementioned Rh-catalyzed C-H bond functionalization reactions, resulting in the design of more efficient and robust catalysts, expanded substrate scope, and new transformations.