Cross-talk among oxytocin and arginine-vasopressin receptors: Relevance for basic and clinical studies of the brain and periphery
Zhimin Song,H. Elliott Albers +1 more
TLDR
The increasing body of evidence that exogenously administered and endogenously released OT and AVP can activate each other's canonical receptors is reviewed and the possibility that receptor cross-talk following the synaptic and non-synaptic release of OT andAVP contributes to their distinct roles in the brain and periphery is examined.About:
This article is published in Frontiers in Neuroendocrinology.The article was published on 2017-10-18 and is currently open access. It has received 150 citations till now. The article focuses on the topics: Vasopressin receptor.read more
Citations
More filters
의사 간호사 communication
TL;DR: The Communication program emphasizes theory, research, and application to examine the ways humans communicate, verbally and non-verbally, across a variety of levels and contexts, to understand ourselves, the authors' media, their relationships, their culture and how these things connect.
Journal ArticleDOI
Is Oxytocin “Nature’s Medicine”?
C. Sue Carter,William M. Kenkel,Evan L. MacLean,Steven Ray Wilson,Allison M. Perkeybile,Jason R. Yee,Craig F. Ferris,Hossein P. Nazarloo,Stephen W. Porges,John M. Davis,Jessica J. Connelly,Marcy A. Kingsbury +11 more
TL;DR: Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior and its capacity to shift chemical forms and bind to other molecules make this molecule difficult to work with and to measure.
Journal ArticleDOI
AMPK: Potential Therapeutic Target for Ischemic Stroke.
TL;DR: The basic structure, upstream regulators, and biological roles of AMPK are introduced and the relationship between AMPK and the neurovascular unit (NVU) is analyzed, followed by ethical issues, potential directions, and further prospects of AM PK.
Journal ArticleDOI
FGF21 Signals to Glutamatergic Neurons in the Ventromedial Hypothalamus to Suppress Carbohydrate Intake
Sharon O. Jensen-Cody,Kyle H. Flippo,Kristin E. Claflin,Yavuz Yavuz,Sarah A. Sapouckey,Grant C. Walters,Yuriy M. Usachev,Deniz Atasoy,Matthew P. Gillum,Matthew J. Potthoff +9 more
TL;DR: It is shown that FGF21 acts directly in the ventromedial hypothalamus (VMH) to specifically regulate sucrose intake, but not non-nutritive sweet-taste preference, body weight, or energy expenditure.
Journal ArticleDOI
Complementary Neural Circuits for Divergent Effects of Oxytocin: Social Approach Versus Social Anxiety.
TL;DR: Evidence for neural circuits mediating the effects of OT in appetitive and aversive social contexts is reviewed and it is proposed that distinct but potentially overlapping circuits mediate OT-dependent social approach or social avoidance.
References
More filters
Book
The Rat Brain in Stereotaxic Coordinates
George Paxinos,Charles Watson +1 more
TL;DR: This paper presents a meta-analyses of the determinants of earthquake-triggered landsliding in the Czech Republic over a period of 18 months in order to establish a probabilistic framework for estimating the intensity of the earthquake.
Journal ArticleDOI
The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl,Falk Fahrenholz +1 more
TL;DR: The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.
Journal ArticleDOI
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
TL;DR: OXT and AVP are emerging as targets for novel treatment approaches — particularly in synergistic combination with psychotherapy — for mental disorders characterized by social dysfunction, such as autism, social anxiety disorder, borderline personality disorder and schizophrenia.
Journal ArticleDOI
Social amnesia in mice lacking the oxytocin gene.
Jennifer N. Ferguson,Larry J. Young,Elizabeth F. Hearn,Martin M. Matzuk,Thomas R. Insel,James T. Winslow +5 more
TL;DR: The data indicate that OT is necessary for the normal development of social memory in mice and support the hypothesis that social memory has a neural basis distinct from other forms of memory.
Journal ArticleDOI
Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication
Rainer Landgraf,Inga D. Neumann +1 more
TL;DR: This concept considers neuropeptides in the extracellular fluid of the brain rather than those in the cerebrospinal fluid or plasma as primary signals, triggering a variety of receptor-mediated effects, including those underlying behavioral and neuroendocrine regulation and psychopathology.
Related Papers (5)
The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl,Falk Fahrenholz +1 more
Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior.
Kelly M. Dumais,Alexa H. Veenema +1 more